bioRxiv Biochemistry
@biorxiv-biochem.bsky.social
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biorxiv-biochem.bsky.social
Atom-level backbone engineering preserves peptide function while enhancing stability https://www.biorxiv.org/content/10.1101/2025.10.06.678421v1
biorxiv-biochem.bsky.social
New inhibitors of the Pseudomonas aeruginosa enzyme, PqsE, and methods assessing their potential to induce a conformational change via active site binding https://www.biorxiv.org/content/10.1101/2025.10.07.680923v1
biorxiv-biochem.bsky.social
PANK2-mediated de novo CoA synthesis is required for metabolic switching to fatty acid oxidation https://www.biorxiv.org/content/10.1101/2025.10.07.680981v1
biorxiv-biochem.bsky.social
Structure of Photosystem I-FCP from giant kelp uncovers drivers of antenna evolution across the red lineage https://www.biorxiv.org/content/10.1101/2025.10.07.680316v1
biorxiv-biochem.bsky.social
Structural and biochemical basis for cannabinoid cyclase activity in marine bacterial flavoenzymes https://www.biorxiv.org/content/10.1101/2025.10.07.680811v1
biorxiv-biochem.bsky.social
Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism https://www.biorxiv.org/content/10.1101/2025.10.07.680924v1
biorxiv-biochem.bsky.social
Structural characterization of hibernating ribosomes in four Gram-negative pathogenic bacteria https://www.biorxiv.org/content/10.1101/2025.10.07.680626v1
biorxiv-biochem.bsky.social
Area-Based Selection of Binding Interfaces for Structural Prediction of Protein-Protein Complexes https://www.biorxiv.org/content/10.1101/2025.10.07.680849v1
biorxiv-biochem.bsky.social
Modulation of serotonergic, dopaminergic and tubulin-associated pathways by tannin-free natural products in Caenorhabditis elegans reveals effective anthelmintic drug targets https://www.biorxiv.org/content/10.1101/2025.10.05.679051v1
biorxiv-biochem.bsky.social
Quantitative Substrate Kinetics Screening: One-Pot LC/MS Based Approach to Map Protease Specificity https://www.biorxiv.org/content/10.1101/2025.10.06.680748v1
biorxiv-biochem.bsky.social
Mapping Structural Constraints and Adaptive Potential in a Capsule-Degrading Phage Tailspike Protein https://www.biorxiv.org/content/10.1101/2025.10.06.680778v1
biorxiv-biochem.bsky.social
Structurally Informed Fitness Landscapes for Surveillance of Emerging PRRSV Variants https://www.biorxiv.org/content/10.1101/2025.10.06.680729v1
biorxiv-biochem.bsky.social
Geographical Origin and Variety Differentiation of Kava (Piper methysticum) using Artificial Neural Network with FTIR Spectroscopy: A Novel Method https://www.biorxiv.org/content/10.1101/2025.10.05.679113v1
biorxiv-biochem.bsky.social
Myoglobin leaching into the serum of IDA mice is driven by the high activation of sGC under anemic conditions which induces myoglobin expression https://www.biorxiv.org/content/10.1101/2025.10.03.680120v1
biorxiv-biochem.bsky.social
Glutamine-Dependent Slc25a39-Nrf2 Axis Couples Mitochondrial Dynamics with Metabolic Reprogramming to Establish Myogenic Commitment https://www.biorxiv.org/content/10.1101/2025.10.02.680066v1
biorxiv-biochem.bsky.social
Cryo-EM structure of the FtsH periplasmic domain reveals functional dynamics https://www.biorxiv.org/content/10.1101/2025.10.03.679995v1
biorxiv-biochem.bsky.social
Greatwall depletion from Xenopus oocytes reveals a key role of the cyclin B/CDK1-PP2A-B55 balance in the coordination of meiotic events https://www.biorxiv.org/content/10.1101/2025.10.03.680315v1
biorxiv-biochem.bsky.social
Clinically observed RASA1 missense mutants exhibit diverse RasGAP protein behaviors https://www.biorxiv.org/content/10.1101/2025.10.03.680326v1
biorxiv-biochem.bsky.social
Biochemical assessment of α-α-subunit interactions of Nav1.5 in a heterologous expression system https://www.biorxiv.org/content/10.1101/2025.10.02.679760v1
biorxiv-biochem.bsky.social
Quantitative Prevalence, Chemical Speciation, and ECM-Embedded Networks of Biogenic Silicon in Animal Tissues Revealed by Refined Analytical Methods https://www.biorxiv.org/content/10.1101/2025.10.02.679922v1
biorxiv-biochem.bsky.social
Cathepsin K as a Key SARS-CoV-2 Cell Entry Protease and Dual-Inhibition Target https://www.biorxiv.org/content/10.1101/2025.10.03.680348v1