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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 3h

Deconvolving mutation and selection reveals stage-specific drivers of thyroid cancer https://www.biorxiv.org/content/10.1101/2025.10.08.681166v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 4h

Co-encapsulated liposomal formulations of tubacin and erlotinib.HCl: a comprehensive stability strategy https://www.biorxiv.org/content/10.1101/2025.10.08.681158v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 4h

Histology and spatial transcriptomic integration revealed infiltration zone with specific cell composition as a prognostic hotspot in glioblastoma https://www.biorxiv.org/content/10.1101/2025.10.08.681087v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 11h

Riluzole as a Dual-Targeted Radiosensitizer for Osteosarcoma: Targeting Tumor Cells and Angiogenic Vasculature to Enhance Single High Dose Radiotherapy Efficacy https://www.biorxiv.org/content/10.1101/2025.10.07.681036v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 12h

RUNX1T1-HDAC Reprogramming of the HOX Code Signaling Drives a Targetable Pan-Cancer Lineage Plasticity https://www.biorxiv.org/content/10.1101/2025.10.07.681000v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 13h

RET Receptor Tyrosine Kinase Promotes Breast Cancer Metastasis to the Brain and RET Inhibitors Pralsetinib and Selpercatinib Suppress Breast Cancer Brain Metastases https://www.biorxiv.org/content/10.1101/2025.10.07.680986v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Reduced CSF1R expression in myeloid cells has limited impact on chronic lymphocytic leukemia progression https://www.biorxiv.org/content/10.1101/2025.10.07.680920v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Unveiling the temporal impact: Exploring dynamic changes in the paediatric solid tumour immune microenvironment through time https://www.biorxiv.org/content/10.1101/2025.10.07.680325v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Rapid expansion of podoplanin-positive fibroblasts following radiation limits the anti-tumour CD8+ T-cell response to radiotherapy. https://www.biorxiv.org/content/10.1101/2025.10.07.680949v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Bovine colostrum-derived extracellular vesicles impair cancer cell proliferation through transcriptional repression. https://www.biorxiv.org/content/10.1101/2025.10.07.680845v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Targeting Kinases to Reshape the Immunopeptidome landscape in Chronic Myeloid Leukemia https://www.biorxiv.org/content/10.1101/2025.10.07.680859v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Identifying tissue states by spatial protein patterns related to chemotherapy response in triple-negative breast cancer https://www.biorxiv.org/content/10.1101/2025.10.06.680783v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

EGFR-targeted and MMP-activated membranolytic peptides derived from Polybia paulista MP1 kill cancer cells specifically in vitro and reduce tumour growth in vivo https://www.biorxiv.org/content/10.1101/2025.10.07.680850v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Voxel-accurate MRI-microscopy correlation enables AI-powered prediction of brain disease states https://www.biorxiv.org/content/10.1101/2025.10.06.680637v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Identification of Expressed Endogenous Retroviral Element Associated Long Terminal Repeats in Devil Facial Tumour Cells https://www.biorxiv.org/content/10.1101/2025.10.06.679394v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

The novel curcumin analogue AKT-100 targets mutant p53 in gynecologic cancer cells https://www.biorxiv.org/content/10.1101/2025.10.06.680794v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

The Utility of Fibroblast Co-culture for the Maintenance of Episomes in Human Papillomavirus-Associated Cancer Models https://www.biorxiv.org/content/10.1101/2025.10.06.680765v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Intermediate tissue oxygen level is required to observe murine FLASH skin sparing https://www.biorxiv.org/content/10.1101/2025.10.06.680759v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 1d

Sensitivity to ATR-CHK1 pathway inhibition in AML/MDS is enhanced by SRSF2 mutations and reduced by RUNX1 loss https://www.biorxiv.org/content/10.1101/2025.10.06.680457v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 2d

Age distinguishes selection from causation in cancer genomes https://www.biorxiv.org/content/10.1101/2025.10.06.680730v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 2d

Differential Impact of Lymphocytes on Radiation Response in Autochthonous versus Transplant Sarcomas in Syngeneic Mice https://www.biorxiv.org/content/10.1101/2025.10.05.680584v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 2d

Leveraging WNT Hyperactivation to Kill Colorectal Cancer While Rejuvenating Healthy Intestine. https://www.biorxiv.org/content/10.1101/2025.10.05.680591v1

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 2d

Modulating p38MAPK recalibrates sensitivity of drug-resistant pancreatic adenoductal carcinoma cells toward chemotherapy and correlate with improved outcome in PDAC patients: Experimental and metadata evidence https://www.biorxiv.org/content/10.1101/2025.10.04.680430v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 2d

Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive disease https://www.biorxiv.org/content/10.1101/2025.10.04.680402v1

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 2d

Functional interrogation uncovers a critical role for a high-plasticity cell state in lung adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.10.03.680232v1