bioRxiv SysBio
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biorxiv-sysbio.bsky.social
Functional Group Composition: The Blueprint for Protein Interactions https://www.biorxiv.org/content/10.1101/2025.10.07.680707v1
biorxiv-sysbio.bsky.social
Multi-team conflict resolution is ineffective for stable decision making https://www.biorxiv.org/content/10.1101/2025.10.06.679762v1
biorxiv-sysbio.bsky.social
Maternal Influenza A Virus Infection Induces Antiviral and Immune Dysregulation in the Placenta and Fetus Without Vertical Transmission https://www.biorxiv.org/content/10.1101/2025.10.06.675688v1
biorxiv-sysbio.bsky.social
Heterogeneous immune recovery after viral response through a dynamical model of feedback-driven persistence and clearance https://www.biorxiv.org/content/10.1101/2025.10.03.680287v1
biorxiv-sysbio.bsky.social
A Priori recognition for biological phenomena prior to empirical understanding https://www.biorxiv.org/content/10.1101/2025.10.02.680169v1
biorxiv-sysbio.bsky.social
Rapid discovery of antiviral targets through dimensionality reduction of genome-scale metabolic models https://www.biorxiv.org/content/10.1101/2025.10.02.679942v1
biorxiv-sysbio.bsky.social
Comparative Analysis of Gene Importance in Escherichia coli Across Growth Conditions https://www.biorxiv.org/content/10.1101/2025.10.02.679994v1
biorxiv-sysbio.bsky.social
Hybrid deep learning-mechanistic modeling of cellular dynamics from a spatiotemporal single-cell atlas https://www.biorxiv.org/content/10.1101/2025.10.02.679951v1
biorxiv-sysbio.bsky.social
Systems analysis reveals neuregulin-1 control of cardiomyocyte size and shape mediated by distinct PI3K and p38 pathways https://www.biorxiv.org/content/10.1101/2025.10.01.679873v1
biorxiv-sysbio.bsky.social
Systematic data-driven genome-scale metabolic model reduction for dynamic bioprocess modeling: CHO cell culture case study https://www.biorxiv.org/content/10.1101/2025.10.02.679947v1
biorxiv-sysbio.bsky.social
Molecular attributes of intrinsically disordered regions in secretomes influence fungal pathogenesis https://www.biorxiv.org/content/10.1101/2025.10.01.679754v1
biorxiv-sysbio.bsky.social
A novel approach to quantify out-of-distribution uncertainty in Neural and Universal Differential Equations https://www.biorxiv.org/content/10.1101/2025.10.01.679743v1
biorxiv-sysbio.bsky.social
Multivariate analysis of glycogenes reveals coordinated regulation of immunoglobulin glycosylation in an immortalized human B cell system https://www.biorxiv.org/content/10.1101/2025.09.30.679651v1
biorxiv-sysbio.bsky.social
Cancer-associated fibroblasts drive metabolic heterogeneity in KRAS-mutant colorectal cancer cells https://www.biorxiv.org/content/10.1101/2025.09.30.679631v1
biorxiv-sysbio.bsky.social
Multi-Scale Kinetics Modeling and Advanced Assay for mRNA-Lipid Nanoparticle Potency Assessment https://www.biorxiv.org/content/10.1101/2025.09.29.679406v1
biorxiv-sysbio.bsky.social
A universal law of thermodynamics-kinetics coupling shapes enzyme allocation and glycolytic efficiency across species https://www.biorxiv.org/content/10.1101/2025.09.29.679393v1
biorxiv-sysbio.bsky.social
Mass spectrometry-based proteomic and glycoproteomic drafts of fifteen human body fluids https://www.biorxiv.org/content/10.1101/2025.09.29.679374v1
biorxiv-sysbio.bsky.social
Cell-type-agnostic differential gene expression uncovers conserved principles of cellular regulation https://www.biorxiv.org/content/10.1101/2025.09.29.679285v1
biorxiv-sysbio.bsky.social
Plasma nirmatrelvir and molnupiravir concentrations required for inhibition of SARS CoV-2 replication differ between rhesus macaques and humans https://www.biorxiv.org/content/10.1101/2025.09.25.678525v1
biorxiv-sysbio.bsky.social
Expanding the iModulon Knowledgebase for Bacillus subtilis: Updated Transcriptome Decomposition Reveals Novel Regulatory Mechanisms https://www.biorxiv.org/content/10.1101/2025.09.29.679290v1
biorxiv-sysbio.bsky.social
Sex-specific microRNA regulators of Parkinson disease: insights from cohort-stratified simulations of compensatory pathway dynamics https://www.biorxiv.org/content/10.1101/2025.09.29.679145v1
biorxiv-sysbio.bsky.social
The effects of increasing renal perfusion pressure on renal hemodynamics, microcirculation,and oxygen metabolism in a septic shock model https://www.biorxiv.org/content/10.1101/2025.09.27.678948v1
biorxiv-sysbio.bsky.social
XomicsDB: a database of paired multi-omics datasets for systems biology https://www.biorxiv.org/content/10.1101/2025.09.27.679001v1