Biosciences Area at Berkeley Lab
@biosci.lbl.gov
600 followers 110 following 210 posts
Official account of the Biosciences Area of @BerkeleyLab Solving challenges in energy, environment, health, and biomanufacturing. Re-post ≠ Endorsement
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biosci.lbl.gov
@jgi.doe.gov sr. engineering associate Berkeley Kauffman was arriving at @berkeleylab.lbl.gov's main site when he encountered this guy out for a morning stroll. "It's aways cool seeing how much wildlife shares the Hill with us!" he noted. #WildlifeWednesday
biosci.lbl.gov
ICYMI: @berkeleylab.lbl.gov is integrating artificial intelligence, automation, and powerful data systems to transform the speed and scale of discovery across scientific disciplines. Read about 8 ways we're using AI to make research faster, smarter, and more impactful. go.lbl.gov/AI_listicle
How AI and Automation are Speeding Up Science and Discovery
Berkeley Lab is transforming research across disciplines from energy to materials science and more, strengthening American innovation and the nation’s scientific edge.
newscenter.lbl.gov
biosci.lbl.gov
We are chuffed to have 6 postdocs representing #TeamBioSci in the 8th annual @berkeleylab.lbl.gov  Research SLAM tomorrow, Thurs Sept 18 @ 3 PM PDT! Lab staff can attend live on the Hill or tune in virtually and cast votes for the People's Choice Award. Everyone else, watch this space for updates!
Clockwise from top left: Thasneem Frousnoon, Laura Cook, Marta Cerruti, Jacob Rapp, Heejung Cho, and Jaya Tripathi.
biosci.lbl.gov
Congratulations to #BioMBIB faculty scientist Susan Marqusee, who was named to The Protein Society's inaugural Fellows class. Susan is a professor of biochemistry, biophysics and structural biology @ucberkeleyofficial.bsky.social  and Director of @qb3-berkeley.bsky.social .
Left: The Protein Society 2025 Fellows logo. Right: Woman with short auburn hair wearing a colorful scarf and black top.
biosci.lbl.gov
Hira Lesea lived many lives—from punk rocker to retreat chef—before becoming a sr. research associate in #BioEGSB. These days, she's into cultivating a sense of collaborative creativity, both in her work @berkeleylab.lbl.gov  and in her personal life. Read her story: go.lbl.gov/lesea #TeamBioSci
Woman with long wavy brown hair and bangs wearing safety goggles, white lab coat, and blue gloves holding a petri dish in a laboratory setting.
Reposted by Biosciences Area at Berkeley Lab
axelvisel.bsky.social
Hiding in plain sight - how close are we to mapping ALL 🧬enhancers🧬 in the genome?

Our new paper by Mannion et al. takes a systematic look at "hidden enhancers" and why they remain so hard to find. With @mosterwalder.bsky.social, @jlopezrios.bsky.social & many more

www.nature.com/articles/s41...
A busy tool wall in a shed. At the bottom there are instructions saying "Find the 10 hidden enhancers!" Across the wall between the tools are 10 enhancers, represented as DNA helices, but they are difficult to find in the style of a "hidden object" puzzle. Original photo by Lachlan Donald, https://www.flickr.com/photos/lox/9408028555
Reposted by Biosciences Area at Berkeley Lab
jgi.doe.gov
Setsuko Wakao of @berkeleylab.lbl.gov will map how diatoms, which produce intricate glass-like cell walls that could inspire new biomaterials, regulate biomineralization processes by identifying genes and regulatory proteins controlling silica formation.
jointgeno.me/FY25FG
A headshot sits beside the researcher's name and affiliation, with the project title below: Mapping the transcriptional regulators of silica biomineralization in diatoms
biosci.lbl.gov
A team at Indiana University, Bloomington, used beamline 8.2.2 @als.lbl.gov  to perform x-ray protein crystallography to resolve the structure of the RNA cloverleaf-protein complex, which plays a critical role in viral replication.

👉 go.lbl.gov/cloverleaf
Digital rendering of coxsackievirus.
biosci.lbl.gov
We are hiring! Come join #TeamBioSci and help us bring science solutions to the world @berkeleylab.lbl.gov.

Kanupriya Pande's group in #BioMBIB has an opening for a Computational Postdoctoral Fellow (cryo-EM).

https://lbl.taleo.net/careersection/2/jobdetail.ftl?job=104578
biosci.lbl.gov
Researchers @scripps.edu used the BCSB macromolecular crystallography beamline 5.0.2 @als.lbl.gov to characterize a protein from a modern shark gene that explains the evolution of the adaptive immune system shared by all vertebrates. #BioMBIB

🦈 go.lbl.gov/bcsb-shark
A nurse shark against a background of clear blue water.
biosci.lbl.gov
Congratulations to the SIBYLS beamline team on being recognized with the 2025 Klaus Halbach Award for Innovative Instrumentation for pioneering the development of time-resolved, high-throughput, small-angle x-ray scattering (SAXS) for collection of data from biological samples @als.lbl.gov.
biosci.lbl.gov
A study led by #BioBSE researchers sheds light on the risks cosmic rays pose to the behavioral health of astronauts. The results suggest a paradigm shift away from DNA as the target for damage by certain light ions, which abound in outer space.
Read more: go.lbl.gov/ure3ga
Headshot of Andrew Wyrobek, a retiree affiliate biophysicist in the Biological Systems & Engineering Division, and a quote reading "It’s a paradigm shift away from the nucleus, away from DNA, away from chromosomes, towards something small and thin" overlaid on an image of cosmic radiation emitting from the Cassiopeia A supernova remnant, captured on NASA's Fermi Gamma-ray Space Telescope. (Credit: NASA/DOE/Fermi LAT Collaboration, CXC/SAO/JPL-Caltech/Steward/O. Krause et al., and NRAO/AUI)
biosci.lbl.gov
#BioEGSB's @pcronald.bsky.social received the President’s Award for Advancement of Common Good from @stanford.edu for her research on environmental stress resilience in rice, which led to the development of flood-tolerant rice now grown by +6M farmers in SE Asia. https://go.lbl.gov/ronald-stanford
Reposted by Biosciences Area at Berkeley Lab
jgi.doe.gov
Improvements to DAP-seq technology enable it to handle larger genomes and could expand opportunities for bioenergy and bioengineering applications—via multiplexed assays and data integration with single-cell gene expression maps.

Full story: jgi.doe.gov/user-science...

@axelvisel.bsky.social 🖥️🧬 🌱
DAP-seq Drives Robust Mapping of Gene Regulation | Joint Genome Institute
Multi-species assays yield an unprecedented view of plant evolution and adaptation.
jgi.doe.gov
biosci.lbl.gov
A team led by scientists @ucdavis.bsky.social, that included Daniil Prigozhin of #BioMBIB, used AI to help plants recognize a wider range of bacterial threats. The approach may lead to new ways to protect crops like tomatoes and potatoes from devastating diseases. go.lbl.gov/plant-immune-upgrade
Photo showing three potato plants growing in soil: the ones on the left and right are healthy; the one in the middle is wilted due to the bacterium Ralstonia solanacearum. Credit: Amilcar Sanchez
biosci.lbl.gov
Congratulations to @jenniferdoudna.bsky.social on being the 2026 recipient of the @acs.org's Priestley Medal! Doudna was recognized for her high-impact discoveries on #RNA molecules with enzymatic functions, including the development of #CRISPR 🧬 ✂️.

More 👉 go.lbl.gov/doudna-priestly
📷 Glenn Ramit
Doudna in a laboratory setting holding model of CRISPR by Glenn Ramit/Innovative Genomics Institute
biosci.lbl.gov
Ruiwen Hu, a postdoc in #BioEGSB, attended #LiNo25 in #Chemistry as part of the UC President’s annual fellowship program. The event “offered a rare opportunity to engage directly with some of the world’s foremost scientific minds," including Nobel Laureate Moungi Bawendi (pictured with Hu).
biosci.lbl.gov
Take a few minutes to watch @jgi.doe.gov postdoc Yumary Vasquez talk abt "going viral" in a BIG way at the National Lab SLAM last March. Learn how infections from giant viruses can impact our water, air, soil, even the gut microbiome!

youtu.be/vDgS4gGUwvE?...

#FlashbackFriday @berkeleylab.lbl.gov
Yumary Vasquez - "These viruses are going viral (and protecting our ecosystems, too!)"
YouTube video by National Lab SLAM
youtu.be
biosci.lbl.gov
It's fascinating to watch the @berkeleylab.lbl.gov riggers at work in the @als.lbl.gov!
lbnlengineering.lbl.gov
See our incredible rigging team in action at the @als.lbl.gov! More about roof blocks here: physicalsciences.lbl.gov/2025/07/28/a...

Video: Thor Swift, Berkeley Lab
biosci.lbl.gov
Join #TeamBioSci & help us bring science solutions to the world at @berkeleylab.lbl.gov!

We are #hiring an Advanced Analysis Manager & Research Associate Principal at @jgi.doe.gov, DevOps Software Engineer at @kbase.us & a computational postdoc for #cryoEM in #BioMBIB.

go.lbl.gov/bioscijobs
A card with two illustrated scientists that reads, "We are hiring! Join #TeamBioSci Learn more at go.lbl.gov/bioscijobs."
Reposted by Biosciences Area at Berkeley Lab
biosci.lbl.gov
Researchers from Novartis Biomedical Research used a #BioMBIB -run beamline at the @als.lbl.gov to confirm the structure of an engineered immune system protein that could open new opportunities to treat inflammatory bowel disease.

go.lbl.gov/atg38j

#IBD #AcceleratingScience @berkeleylab.lbl.gov
A molecular rendering of the engineered graft of IL-10 with an antibody (GFT-IL10M). Structural analysis of GFT-IL10M using x-ray crystallography at the ALS provided insight into its improved anti-inflammatory properties. The schematic illustrates that the designed biotherapeutic minimized pro-inflammatory signaling observed in wild-type IL-10. (Credit: Michael DiDonato/Novartis Biomedical Research)