Lightnews — Scholar-powered news

Brotman Baty Institute @brotmanbaty.bsky.social · Aug 26

BBI's annual Long-Read Sequencing Symposium is set for Sept. 16th, 10 am to 4:30 pm; poster session - 11:45 to 12:50. Location is UW's Foege Hall South, 3720 15th Ave NE, Seattle. Visit Redcap for details/registration; registration ends Sept. 5 at 12 noon.
redcap.iths.org/surveys/?s=8...

Reposted by Brotman Baty Institute

Atlas of Variant Effects Alliance @varianteffect.bsky.social · Jun 16

We’ve got two exciting VESS speakers lined up for July 1 🤩
🎙️Daniel Zimmerman postdoc @pittdeptofmed.bsky.social
🎙️Frederik Filip Vinggaard Stæger @ffstaeger.bsky.social postdoc at Univ. of Copenhagen
Info + Zoom link: varianteffect.org/seminar-series
#Genetics #MedicalGenetics #FunctionalGenomics

4 3

Brotman Baty Institute @brotmanbaty.bsky.social · Jun 16

POSTDOC ALERT: Applications now open for SeaBridge postdoc fellowship; opportunity to work on leading-edge biotech w/researchers at the Seattle Hub for Synthetic Biology.
brotmanbaty.org/news/new-pos...
@marionpepper.bsky.social
@jshendure.bsky.social
@coletrapnell.bsky.social

New Postdoc Fellowship Program Builds on Innovative SeattleHub Research | Brotman Baty Institute

BBI

brotmanbaty.org

4 3

Brotman Baty Institute @brotmanbaty.bsky.social · Jun 5

Zachary Amador, left, scientist w/Seattle Hub for Synthetic Biology, explains to artist Ranger Liu an experiment using DNA - they are collaborating togther in the Fred Hutch SxAffold "encounter" this week among artists & scientists.
@fredhutch.bsky.social
@calliechappell.bsky.social

1 3

Brotman Baty Institute @brotmanbaty.bsky.social · Jun 3

Ranger Liu, artist & physicist working on a Ph.D. in Astronomy at UW, is working w/a SeattleHub researcher as part of SxAffold, the weeklong collaboration among scientists & artists at the Hutch. Photo by Connor O’Shaughnessy / Fred Hutch
alleninstitute.org/division/sea...
@fredhutch.bsky.social

1 2

Brotman Baty Institute @brotmanbaty.bsky.social · Jun 2

TOMORROW - June 3 - at 9 AM - The Variant Effects Seminar Series will feature Ben Li (U of Michigan) & Vahid Aslanzadeh (U of Edinburgh) Details: www.varianteffect.org/seminar-seri...
@varianteffect.bsky.social
@uwmedicine.bsky.social

2 3

Brotman Baty Institute @brotmanbaty.bsky.social · May 22

MS 2025 Update: @cwjpugh.bsky.social presents on 'Breaking the Scaling Barrier in Protein Variant Effect Prediction."
@jonnyfrazer.bsky.social
@leastarita.bsky.social
@dougfowler.bsky.social
@varianteffect.bsky.social
@fritzroth.bsky.social
@muffley.bsky.social
#VariantEffect25

bsky.app

Reposted by Brotman Baty Institute

Isabelle Zane @isabellease.bsky.social · May 22

@cwjpugh.bsky.social at #VariantEffect25

8 19

Brotman Baty Institute @brotmanbaty.bsky.social · May 21

Update from MSS 2025 in Barcelona: Dave Adams of Wellcome-Sanger presents on how genetic variation impacts cancer disease risk. Photo: Jonathan Frazer @jonnyfrazer.bsky.social
@varianteffect.bsky.social
@davidjadams.bsky.social
@lindorfflarsen.bsky.social
@sangerinstitute.bsky.social

3

Brotman Baty Institute @brotmanbaty.bsky.social · May 20

MSS 2025 is underway in Barcelona. Many thanks to Jonathan Frazier for posting updates regularly. Several BBI researchers are participating.
@jonnyfrazer.bsky.social
@leastarita.bsky.social
@dougfowler.bsky.social
@muffley.bsky.social
@shawnfayer.bsky.social
#VariantEffect25

1 3

Reposted by Brotman Baty Institute

Jonathan Frazer @jonnyfrazer.bsky.social · May 20

Let’s get this party started! Kicking off workshop 1 of #VariantEffect25 we have Albert Escobedo — From Fitness to Free Energy: Thermodynamic Modeling of Protein DMS Data for Accurate Genetic Prediction with MoCHI 🍡🧬

4 4

Brotman Baty Institute @brotmanbaty.bsky.social · May 16

'Science can feel like magic. When you begin to understand how and why things work, it’s incredible.'
Learn more about Katie Partington, an 'intellectually adventurous' promising young scientist in the lab of BBI's Dr. Doug Fowler.
brotmanbaty.org/news/promisi...
@dougfowler.bsky.social
@hmc.edu

3 6

Brotman Baty Institute @brotmanbaty.bsky.social · May 15

New paper by UW Medicine's Colin Pritchard clears up confusion on treating ‘passenger’ vs. ‘driver’ mutations in BRCA1 and 2 genes. Learn more.
ascopubs.org/doi/pdf/10.1...
@uwmedicine.bsky.social
@ascocancer.bsky.social

1

Brotman Baty Institute @brotmanbaty.bsky.social · May 14

Hi Jonathan, we at BBI are looking forward to your posts next week from MSS 2025 from Barcelona. Cheers!
@jonnyfrazer.bsky.social
@varianteffect.bsky.social
@bennibolo.bsky.social
#VariantEffects25

1 4

Brotman Baty Institute @brotmanbaty.bsky.social · May 13

HUGE congrats Lara Muffley - honored w/ UW Distinguished Staff Award for Collaboration - advancing world-class research on genetic variants on behalf of BBI
brotmanbaty.org/news/bbis-la...
@varianteffect.bsky.social
@leastarita.bsky.social
@dougfowler.bsky.social
@mehurles.bsky.social

7

Brotman Baty Institute @brotmanbaty.bsky.social · May 8

Are you or someone you know affected by Hemophilia B? BBI's Drs. Jill Johnsen & Doug Fowler have advanced genetic understandinng of the blood disorder. Learn more.
brotmanbaty.org/news/new-mut...
@uwmedicine.bsky.social
@dougfowler.bsky.social
@hemophilia.bsky.social

New Mutational Scanning Method Advances Genetic Understanding of Hemophilia B | Brotman Baty Institute

BBI

brotmanbaty.org

1 1

Brotman Baty Institute @brotmanbaty.bsky.social · May 2

AI & Precision Medicine: The Stuart and Molly Sloan Precision Oncology Institute at Fred Hutch Cancer Center is hosting a symposium on AI, on Tuesday, May 20. Learn how AI is shaping treatment, diagnosis & prevention strategies for cancer.
@fredhutch.bsky.social
www.fredhutch.org/en/events/st...

Stuart and Molly Sloan Precision Oncology Institute AI Symposium

The Stuart and Molly Sloan Precision Oncology Institute is hosting an AI Symposium, which will feature a panel of local and national leaders in the field who will deliver talks and join in discussions...

www.fredhutch.org

1 1 3

Brotman Baty Institute @brotmanbaty.bsky.social · May 1

Next up for the Variant Effects Seminar Series: Tuesday, 6 May, 9am (Pacific) w/ Timothy Tan (U of Illinois) & Mustafa Tekpinar (Van Yüzüncü Yıl University).
Details: www.varianteffect.org/seminar-seri...
@uwgenome.bsky.social
@varianteffect.bsky.social

1

Brotman Baty Institute @brotmanbaty.bsky.social · Apr 25

Check out the newly refreshed Atlas of Variant Effects website: www.varianteffect.org/for A smoother & more intuitive experience. Kudos to the Wellcome Sanger Webdev team for their work
@sangerinstitute.bsky.social

1

Brotman Baty Institute @brotmanbaty.bsky.social · Apr 21

One never knows the power and persuasion of elementary school teachers. Jonas ("Gus") Gustafson's fifth grade instructor 'allowed me to establish a life-long knack and passion for STEM.’
@uwmedicine.bsky.social
@danrdanny.bsky.social
brotmanbaty.org/news/promisi...

1 3

Brotman Baty Institute @brotmanbaty.bsky.social · Apr 16

New study in Genome Biology: Guidelines for releasing a variant effect predictor - 'enhance personalized medicine & genetic disease understanding, aligning w/calls for standardized, rigorous VEP practices in genomic medicine'
genomebiology.biomedcentral.com/articles/10....
@broadinstitute.org

Guidelines for releasing a variant effect predictor - Genome Biology

Computational methods for assessing the likely impacts of mutations, known as variant effect predictors (VEPs), are widely used in the assessment and interpretation of human genetic variation, as well...

genomebiology.biomedcentral.com

1

Brotman Baty Institute @brotmanbaty.bsky.social · Apr 14

Looking Ahead: Mutational Scanning Symposium 2025, May 21-23, Barcelona, features Kresten Lindorff-Larsen addressing interface between variant effects & interpretation. Learn more: brotmanbaty.org/news/spotlig...
@varianteffect.bsky.social
@lindorfflarsen.bsky.social
@bennibolo.bsky.social

3 6

Brotman Baty Institute @brotmanbaty.bsky.social · Apr 9

'The lives of cells, recorded:' Nature perspective reflects foundational principles of Seattle Hub & 'further(s) our understanding of cell decisions over time, given their cellular ancestry & past cell trajectories.'
@naturegenet.bsky.social
@jshendure.bsky.social
brotmanbaty.org/news/nature-...

Nature Perspective Reflects Foundational Principles of Seattle Hub | Brotman Baty Institute

BBI

brotmanbaty.org

1

Brotman Baty Institute @brotmanbaty.bsky.social · Mar 31

TOMORROW - 9 am (Pacific) Variant Effects Seminar - Presentations by Joyce Kang (Harvard-MIT) and Yiyun Rao (Penn State)
@broadinstitute.org
@pennstateuniv.bsky.social
@varianteffect.bsky.social

Learn more: www.varianteffect.org/seminar-series

3 4

Brotman Baty Institute @brotmanbaty.bsky.social · Mar 27

Mark your calendars now. The next variant effects seminar is Monday, 1 April, 9 am (Pacific), featuring Joyce Kang @harvard.edu @broadinstitute.org & Yiyun Rao @pennstateuniv.bsky.social.
@varianteffect.bsky.social
Learn more:
www.varianteffect.org/seminar-series

3 4