Lightnews — Scholar-powered news

Bryan Welm @bryanwelm.bsky.social · Jul 10

Thanks Mike!

Bryan Welm @bryanwelm.bsky.social · Jul 10

Finished another bronze of a T-cell attacking a cancer cell. This one is heading to Max Krummel at UCSF, who did some of the early studies on CTLA4 immunotherapy. #sciart.

Bronze sculpture of a T-cell attacking a cancer cell.

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Reposted by Bryan Welm

Huntsman Cancer Institute @huntsmancancer.bsky.social · May 20

We are proud to share that @alanawelm.bsky.social, PhD, has been named chair of Oncological Sciences at @utah.edu. A global leader in breast cancer research, she brings deep vision, collaboration, and impact to this new role. Please join us in congratulating Dr. Welm. Learn more: bit.ly/3H3GqB3

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Bryan Welm @bryanwelm.bsky.social · Apr 12

While it’s perhaps trivial in these times, I do hope my art inspires, and reminds colleagues of the beauty of their work. Here is a PAS-B domain in steel and copper that is in the final stages of its build.

A metal sculpture of a PAS-B domain found in proteins. The sculpture represents the protein structure at 50 million times the actual size.

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Reposted by Bryan Welm

The Company of Biologists @biologists.bsky.social · Mar 26

Today is the last day to vote in @the-node.bsky.social @focalplane.bsky.social image competition. Select your favourite at bit.ly/4bFDENR by Wednesday 26 March 11:59pm GMT.

Attending Biologists @ 100? You can view all entries and vote in Hall 2.

Vote for your favourite image in the Node–FocalPlane image competition - the Node

Browse through the gallery of the 15 shortlisted images and vote for your favourite image by Wednesday 26 March.

bit.ly

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Reposted by Bryan Welm

Sarah Moser @sarahmoser.bsky.social · Mar 3

BRCA1 turned 30 🎉
To celebrate, Jos Jonkers and I explored three decades of BRCA1 research - what we’ve learned about its biology, its role in tumorigenesis and future directions to improve the life of BRCA1 mutation carriers.
Now out in Cancer Discovery ⬇️: aacrjournals.org/cancerdiscov...

Thirty Years of BRCA1: Mechanistic Insights and Their Impact on Mutation Carriers

Abstract. Thirty years ago, the cloning of the first breast cancer susceptibility gene, BRCA1, marked a milestone in our understanding of hereditary breast and ovarian cancers. This discovery initiate...

aacrjournals.org

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Reposted by Bryan Welm

Karolin Luger @nucleosomepolice.bsky.social · Mar 1

🧪what with the demolition of #NIH funded #research, where, dare I ask, are our friends from #bigpharma? y'all good? mooched enough off of public-access NIH-funded research? Stocked up with PhD level scientists who were trained on NIH training grants to tide you over until Academia comes back?

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Bryan Welm @bryanwelm.bsky.social · Feb 25

I also appreciate the employees and work of the #NPS and #BLM to safeguard our national treasures. Adding a recent picture from Yellowstone.

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Reposted by Bryan Welm

Karolin Luger @nucleosomepolice.bsky.social · Feb 25

This!!!

David Green, PhD @ecologistgreen.bsky.social · Feb 19

I think the biggest lie being told right now is that one of the wealthiest countries in the world cannot afford to invest in science, education, and the environment.

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Reposted by Bryan Welm

Alana Welm @alanawelm.bsky.social · Feb 24

I’m really grateful to live in a place where I can go out the backdoor for a slow paced 10mi run to clear my head of all this federal nonsense! I was especially lucky today to have a snowmobile track to run over; last week I had to break my own path. 1/2

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Reposted by Bryan Welm

Alana Welm @alanawelm.bsky.social · Feb 24

And, at the end I saw a bald eagle perched on a tree! I hope you all can find whatever works to clear your head and get ready for another week of finding innovative ways to do, and fight for, science!

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Reposted by Bryan Welm

CantlonLab @cantlonlab.bsky.social · Feb 18

Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠

sciencehomecoming.com

Science Homecoming

sciencehomecoming.com

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Reposted by Bryan Welm

Harmit Singh Malik @harmitmalik.bsky.social · Feb 15

Someone awesome in my circle shared some terrific news with me today but was hesitant to do so because of all that is going on in the science world.

It may appear insensitive that you are celebrating when other colleagues are struggling but I entreat you to celebrate & share good news. 1/

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Reposted by Bryan Welm

Katie Sandlin @kmsandlin.bsky.social · Feb 14

Today, along with 2,000 other NIH employees, I had to clear out my office 😭

It was truly the honor of my life to work with such incredibly passionate people focused on improving human health. I’ve never experienced a more positive culture where *everyone* cared about their job and serving others.

Office desk without any personal items or decor

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Bryan Welm @bryanwelm.bsky.social · Feb 15

Great article by Harold Varmus!

Karen S Wilcox, PhD (she/her) @karenswilcoxphd.bsky.social · Feb 15

Excellent opinion piece from Nobel Laureate ans former director of NIH, Dr. Harold Varmus. A call to arms. www.nytimes.com/2025/02/14/o...

Opinion | American Science is Under Attack

The Trump administration hobbles research and endangers the public health.

www.nytimes.com

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Reposted by Bryan Welm

Jeremy Berg @jeremymberg.bsky.social · Feb 8

University GCs are, I'm sure, talking about this or getting some rest (if they can) for a long battle ahead.

I would suggest that we don't become armchair lawyers here.

Let's focus on how to communicate the impact of implementing this on health, our communities, and the ability of the US to lead.

Maxence Nachury @nachury.bsky.social · Feb 8

How legally binding is the F&A agreement? Any University General Councel out there care to opine?

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Reposted by Bryan Welm

Dr Craig R McClain @drcraigmc.bsky.social · Jan 29

Somewhere in the U.S., there’s a scientist staring at their NSF/NIH grant application wondering why they bother. This post is for you. Science and society both need you. Hang in there and know there is a whole community supporting you.

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Bryan Welm @bryanwelm.bsky.social · Jan 16

Here’s a review on PDX models and functional precision medicine. From the amazing lab of Alana Welm.

Nature Reviews Cancer @natrevcancer.nature.com · Jan 16

#Review 🚨

In case you missed it, here Alan Welm & co discuss the importance of #PDX models for functional precision oncology and how integrating these with #AI can enhance their utility for personalizing cancer treatment. 🐁🤖🔬

@huntsmancancer.bsky.social

www.nature.com/articles/s41...

PDX models for functional precision oncology and discovery science - Nature Reviews Cancer

Patient-derived xenograft (PDX) models are valuable surrogates for drug testing in precision oncology. In this Review, Welm and colleagues outline the opportunities and challenges of PDX models, discu...

www.nature.com

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Bryan Welm @bryanwelm.bsky.social · Jan 11

Made some changes to the sculpture of a T-cell attacking a cancer cell. Repositioned the cancer cell in a vertical stance. Showing the attachment of the cells after the change. These are bronzes with a layer of steel brazed where the cells attach. Magnets hold them together. Work in progress. 🐡

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Bryan Welm @bryanwelm.bsky.social · Jan 6

I agree! Great that Janet is carrying the torch for this!

Karolin Luger @nucleosomepolice.bsky.social · Jan 6

David Goodsell is a national treasure. There. It needed to be said. And @jiwasa.bsky.social will be amazing in carrying forward the tradition. #structuralbiology and the @rcsbpdb.bsky.social is lucky to have them.

RCSB Protein Data Bank @rcsbpdb.bsky.social · Jan 6

After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month. We are very grateful for his service.
@jiwasa.bsky.social will continue the series, beginning with January's article on Assembly Line Polyketide Synthases
Details: cdn.rcsb.org/rcsb-pd...

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Bryan Welm @bryanwelm.bsky.social · Dec 25

That’s what I think. It has to do with the depth of the oxide within the copper, which is controlled by the amount of heat. Wavelengths of light reflect off different oxide layers and can interfere with each other, resulting in subtraction of some wavelengths/colors.

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Bryan Welm @bryanwelm.bsky.social · Dec 25

got some answers. 1. metalworking shop; 2. I braze/weld copper for some sculptures. Sometimes the copper gets so hot a molten drop falls and goes splat on the floor; 3. The different oxidation states might be from how quickly they cool eg. if they land on the metal welding table vs the floor.

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Bryan Welm @bryanwelm.bsky.social · Dec 24

A cellular Christmas tree made from molten copper drops. Splats of copper sometimes happen when welding and they often take the shape of different cell types. I collect these off my shop floor because they look cool…….and yes, they make my sciency senses tingle!

Merry Christmas!

#SciArt

Splatters of molten copper arranged into the shape of a Christmas tree. When molten copper drops onto a hard surface they form shapes resembling different cell types.

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Reposted by Bryan Welm

Beata Science Art @beatascienceart.bsky.social · Dec 20

😮🤩 Wow, a completely filled room at our #CellBio2024 #SciArt session! What an amazing evening with inspiring talks about creativity, education and microscopy. Huge thanks to our speakers and audience. Please reach out if you're interested in co-organizing or speaking next year!

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Bryan Welm @bryanwelm.bsky.social · Dec 20

DM and we can chat.