3/3 the emergence of clinical symptoms without altering overall disease risk or progression."

onlinelibrary.wiley.com/doi/10.1002/...

2/3 Unfortunately, coffee did not reduce the overall risk for PD, or how it progressed.

"Our findings indicate a potential protective relationship between coffee consumption and PD onset, suggesting that greater coffee intake may delay ...

"These results suggest that oral CBD treatments can improve memory processes that are impaired due to aging."

Effects of cannabidiol (CBD) treatment on age-related cognitive decline in C57 mice
www.frontiersin.org/journals/agi...

3/3 "In older burn patients, metformin was linked with improved outcomes and no adverse effects, underscoring its safety and efficacy in this population."

Metformin administration improves adverse outcomes in older adult burn patients: a single-centre cohort study www.nature.com/articles/s41...

2/3 Despite having a higher incidence of pre-existing diabetes and hypertension, metformin-treated patients showed improved survival and systematic levels of several organ damage markers were significantly reduced.

3/3 "Higher MDS was associated with lower BPMs over time. This study highlights the role of diet quality in healthy aging and mitigating cardiometabolic risk in older adults."

link.springer.com/article/10.1...

2/3 inverse relationship between blood pressure and diet quality. This is probably due to the high amount of beneficial polyphenols found in the MD as well as the fact that eating healthy "crowds out" processed salty foods which can raise blood pressure.

2/2 ATFS-1 can extend lifespan when expressed at low levels and that this lifespan extension is not dependent on the ability of ATFS-1 to enhance resistance to stress."

royalsocietypublishing.org/rsob/article...

2/2 cognition in older adults at risk for dementia. Angiogenin may protect against cognitive decline, opening new avenues for innovative preventive, or therapeutic interventions."

Blood Angiogenesis Markers and Cognition in Older Adults at Risk for Dementia
journals.sagepub.com/doi/10.1177/...

3/3 Cannabis smoking is associated with persistent epigenome-wide disruptions despite smoking cessation
link.springer.com/article/10.1...

2/3 many of which persist despite cannabis smoking cessation. Epigenetic modulation of genes associated with aging and cancer that remains even after quitting cannabis should serve as a caution that there may be long-lasting epigenetic injury with cannabis smoking."

They recommend that aerobic exercise and resistance training should be more commonly prescribed.

As the authors conclude, "Older adults who become more physically active can potentially add years to their lives as well as higher quality of life to those years."
www.cmaj.ca/content/197/...

Unsurprisingly, the authors tout the health benefits of exercise - not only can 150 mins/week of moderate exercise reduce mortality by 31%, the benefits extend to improved cognition, prevention of falls, functional independence and quality of life.