Center For Cardiometabolic Science
@cardiometabosci.bsky.social
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Center of multi-disciplinary scientists at the University of Louisville striving to uncover the mysteries of the cardiovascular system. www.CenterforCardioMetabolicScience.org
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cardiometabosci.bsky.social
Yesterday, we celebrated the recent success of Dr. Marcin Wysoczynski, who was awarded a five-year NIH R01 grant to study how specific types of neutrophils shape the wound healing response after MI. This award marks the start of a new chapter in our understanding of the failing heart.
cardiometabosci.bsky.social
This review focuses on myocardial metabolic inflexibility in cardiometabolic disease and heart failure with preserved ejection fraction (HFpEF) and discusses potential therapies aimed at improving metabolic flexibility for the treatment of HFpEF.
cardiometabosci.bsky.social
Congratulations to Dr. Nong for his contributions to this new collaborative review article published in iScience. www.sciencedirect.com/science/arti... #cardiosky
cardiometabosci.bsky.social
New publication from the Sansbury lab. This study shows that the ALX/FPR2 signaling axis is necessary for red blood cell homeostasis and that LXA4 activation is important for red pulp macrophage response to acute erythroid stress.
cardiometabosci.bsky.social
A key Image from this publication, led by Collin Wells, a former PhD student of the Hill lab, made the September cover of JMCC www.jmcc-online.com/article/S002...
cardiometabosci.bsky.social
Hot off the press! This latest publication from the Haberzettl lab shows that female mice are protected against cardiometabolic PM2.5 toxicity, possibly by preventing PM2.5-induced pulmonary oxidative stress. physoc.onlinelibrary.wiley.com/doi/10.14814...
cardiometabosci.bsky.social
Too eager to wait? This study shows that E-cigarette exposures in pregnant mice caused ventricular arrhythmias persisting 3 weeks after exposures and labor. Changes in systolic function, catecholamines, and repolarization suggest these effects are derived from persistent sympathoexcitation.
cardiometabosci.bsky.social
Don’t go vaping my heart, especially when pregnant💨 🫀🤰 Want to know why? Find out more in the latest publication by the Alex Carll, PhD, lab in AJP-Heart, led by PhD student, Brittany Reynolds. journals.physiology.org/doi/abs/10.1...
cardiometabosci.bsky.social
Using a robust preclinical rat model of HFpEF, Dr. Andrew Gibb and colleagues identified disruptions in mitochondrial function and metabolism as key contributors to HFpEF pathophysiology. Check out the research manuscript and accompanying editorial out now in #JACCBTS. #cardiosky
cardiometabosci.bsky.social
Today, we have the distinct pleasure of welcoming Dr. Mattia Quattrocelli to the Center. This morning, during his visit, Dr. Quattrocelli presented recent work from his lab examining the relationship between the circadian clock, glucocorticoid receptor, and striated muscle biology. #cardiosky
cardiometabosci.bsky.social
This study shows exercise improves kidney function by increasing microvascular blood volume and altering the kidney's immune cell composition, by increasing the number of resident macrophages in male mice.
cardiometabosci.bsky.social
Does exercise give the kidneys a run for their money? 🏃‍➡️ 🫘 Want to know? Check out the latest publication in AJP-Renal from the laboratory of Dr. Sophia Sears. #kidneysky #renalsky #exercisesky @uoflenvirome.bsky.social @uoflmedicine.bsky.social @apspublications.bsky.social @stevenpjones.bsky.social
cardiometabosci.bsky.social
This study shows that exercise improves kidney function by increasing microvascular blood volume and altering the kidney's immune cell composition, by increasing the number of resident macrophages in male mice.
cardiometabosci.bsky.social
Next week, we will welcome Dr. Mattia Quattrocelli, Assistant Professor from Cincinnati Children's, to our weekly Center conference. Dr. Quattrocelli will present recent work from his laboratory focused on the role of the Carnosine Clock in Aging. We are looking forward to his visit! #cardiosky
cardiometabosci.bsky.social
Congratulations to Ben Doelling, a biochemistry and Molecular Genetics PhD student in the laboratory of Dr. Shahid Baba, for receiving an NIH F31 Fellowship. This project will examine the Biochemical Silencing of Maladaptive Inflammation in Heart Failure. #cardiosky