Carlos Garcia-Batres
@carlosrgb.bsky.social
Reposted by Carlos Garcia-Batres
Excited to share our new publication identifying unique features of CD56bright NK cells in HSCT recipients. Here we explore unique features of CD56bright NK cells in HSCT recipients protected from GVHD, and identify factors that shape their functions: www.cell.com/iscience/ful...
Single cell profiling of hematopoietic stem cell transplant recipients reveals TGF-β1 and IL-2 confer immunoregulatory functions to NK cells
NK cells exhibit diverse functions shaped by cytokines and microenvironments. We identify TGF-β1highCD56bright NK cells linked to protection from GVHT post-HSCT. IL-2 and TGF-β1 drive NK cells to a transient regulatory phenotype with unique transcriptional profiles, highlighting non-canonical regulatory functions can be induced by these cytokines.
www.cell.com
December 12, 2024 at 3:08 AM
Excited to share our new publication identifying unique features of CD56bright NK cells in HSCT recipients. Here we explore unique features of CD56bright NK cells in HSCT recipients protected from GVHD, and identify factors that shape their functions: www.cell.com/iscience/ful...
October 6, 2023 at 1:37 AM