Carlos Castaneda-Alvarez
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ccastanedaal.bsky.social
Carlos Castaneda-Alvarez
@ccastanedaal.bsky.social
Nematologist (PhD). PPN and EPN 🪱 Beneficial Bacteria. Biocontrol
Reposted by Carlos Castaneda-Alvarez
What a way to start the new year with one more submission to BioRxiv. This one is on how GTSF-1 enable RdRP activity in nematodes (for Piwi aficionados: correct, it does not affect Piwi😊)

www.biorxiv.org/content/10.6...
An Evolutionarily Conserved N-terminal Domain of RRF-3 Governs GTSF-1 Binding in Nematodes
GTSF1 is an essential activating cofactor for PIWI proteins in many metazoans. In the nematode Caenorhabditis elegans, however, GTSF-1 does not bind PIWI, but associates with the RNA-dependent RNA pol...
www.biorxiv.org
January 4, 2026 at 2:47 PM