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Collaborative Computational Project for Electron cryo-Microscopy

@ccpem.bsky.social

370 followers 30 following 15 posts

The Collaborative Computational Project for electron cryo-microscopy (CCP-EM) supports users and developers in biological EM. CCP-EM is based at STFC and core funded by MRC both of which are part of UKRI https://www.ccpem.ac.uk/

www.ccpem.ac.uk

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · 9d

Great study of a flexible protein-DNA complex, with contributions from CCP-EM's Agnel.

Laura Spagnolo @lauraspagnolo.bsky.social · May 3

Our work on phiC31 integrase is now on bioRxiv. Joint University of Glasgow and Research Complex at Harwell effort. Funded by BBSRC. @uofglasgow.bsky.social #researchcomplexatharwell #BBSRC

www.biorxiv.org/content/10.1...

Structural basis of DNA recombination catalysis and regulation by phiC31 integrase

Large serine integrases catalyse the insertion (integration) and excision of bacteriophage genomes into and from the genomes of their bacterial hosts via site-specific recombination. The recombination...

www.biorxiv.org

Reposted by Collaborative Computational Project for Electron cryo-Microscopy

VolumeEM @volumeem1.bsky.social · 9d

🌟 Awesome vEM Images Competition deadline extended to Oct 6, 5 PM CT! 🌟

Submit to one or both categories:
1️⃣ The Power of EM
2️⃣ Bringing Meaning to the Data

🏆 $250 for 1st, $100 for 2nd & 3rd (each category)

🔗 www.volumeem.org/awesome-imag...

Details and last year's winning images ⬇️

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · 14d

Still time to register for the inaugural CCP-volumeEM Community Meeting at the Crick on 3rd November www.eventbrite.co.uk/e/towards-a-...

Towards a collaborative computational community for volumeEM

Join us for the inaugural CCP-volumeEM Community Meeting, bringing together researchers, microscopists, biologists and computer scientists.

www.eventbrite.co.uk

Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Jul 17

Applications are now open for the 2025 cohort of CoSeC Fellows (CoSeC is the umbrella organisation for CCPs). CoSeC Fellows will each be awarded funding of up to £3000 and gain access to collaborations across a wide range of research areas. lnkd.in/e2s8ZtDQ

This link will take you to a page that’s not on LinkedIn

lnkd.in

Reposted by Collaborative Computational Project for Electron cryo-Microscopy

CCP-volumeEM @ccp-volumeem.bsky.social · Jul 9

🚨 SAVE THE DATE 🚨
Inaugural CCP-volumeEM Community Meeting, 3rd November 2025 at @crick.ac.uk in London
"Towards a collaborative computational community for volume EM"
Timings: 12pm - 5.30pm, followed by networking reception

#volumeEM #BioImageAnalysis #VEM #CCPvolumeEM #CoSeC

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · May 15

2025 Spring Symposium lectures are now up on our YouTube channel: www.youtube.com/playlist?lis...

CCP-EM Spring Symposium 2025 - YouTube

The 11th annual CCP-EM Spring Symposium was held from the 23-25th April 2025 at the East Midlands Conference Centre, University of Nottingham as a hybrid in-...

www.youtube.com

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · May 7

Raw Zoom recordings of the majority of talks at the DLS BCI and CCP-EM Spring Symposium are available here... www.ccpem.ac.uk/symposium/sp...

2025 Spring Symposium XI – CCP-EM

www.ccpem.ac.uk

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Apr 24

First day of CCP-EM Spring Symposium following a great BCI User Meeting yesterday (and Ceilidh!). Zoom and Slack links at www.ccpem.ac.uk/symposium/sp...

2025 Spring Symposium XI – CCP-EM

www.ccpem.ac.uk

Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Apr 13

Looking forward to teaching at the this great course in the summer in Padova... Register now! school2025.cristallografia.org #cryoEM #structural_biology #crystallography

school2025.cristallografia.org

Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Apr 2

New version of Doppio released today. This include new Servalcat Refine and Servalcat Mask jobs for atomic model building, the latest version of Moorhen and some minor bug fixes www.ccpem.ac.uk/software/dow...

Downloads – CCP-EM

www.ccpem.ac.uk

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Apr 2

We've released a suite of tools profet, EMPIARreader and CAKED. If you want python tools to fetch protein structures, lazy load EMPIAR data and integrate into ML workflows take a look... arxiv.org/abs/2503.13329

PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modelling and machine learning

Ease of access to data, tools and models expedites scientific research. In structural biology there are now numerous open repositories of experimental and simulated datasets. Being able to easily acce...

arxiv.org

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Mar 19

The ever popular EMBO practical course in cryoEM image processing, to be held at Birkbeck College London from 9th to the 16th September, is now open for registrations meetings.embo.org/event/25-cry...

Image processing for cryo-electron microscopy

Cryo electron microscopy (cryo EM) is a major structural biology method for studying macromolecular complexes and cellular structures in their native states. Stable high resolution cryo microscopes, …

meetings.embo.org

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Mar 13

Out now: our preprint with Zach Freyberg, Jiying Ning and Jill Glausier on in situ cryoET of diverse brain tissues (www.biorxiv.org/content/10.1...), featuring a novel approach for preparing lamellae and the use of the CCP-EM framework for subtomogram averaging.

Uncovering synaptic and cellular nanoarchitecture of brain tissue via seamless in situ trimming and milling for cryo-electron tomography

Cell-cell communication underlies all emergent properties of the brain, including cognition, learning and memory. The physical basis for these communications is the synapse, a multi-component structur...

www.biorxiv.org

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Mar 11

CCP-EM are joining forces with our sister projects CCP4, CCPN and CCPBioSim, the DRI-IMB team, see www.sc.stfc.ac.uk/major-invest...

Major investment to establish an innovative research-community driven infrastructure for molecular biology - Scientific Computing, Science and Technology Facilities Council (STFC)

www.sc.stfc.ac.uk

Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Mar 10

Check out the new Moorhen gallery for some cool pics moorhen.org/gallery Moorhen is used by several projects including CCP-EM.

Moorhen

Moorhen is a molecular graphics web application based on the Coot desktop program.

moorhen.org

Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Mar 4

Registration still open for our 11th Spring Symposium 23 – 25 April in Nottingham and virtual www.ccpem.ac.uk/symposium/sp... but limited accommodation remaining!

2025 Spring Symposium XI – CCP-EM

www.ccpem.ac.uk

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Collaborative Computational Project for Electron cryo-Microscopy @ccpem.bsky.social · Mar 4

Hello bluesky people from the Collaborative Computational Project for Electron cryo-Microscopy!

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