Cristian Ruiz-Moreno
@ccruizm.bsky.social
Cancer and molecular biology PhD candidate | Stunnenberg Lab | Prinses Maxima Centrum & Radboud University Nijmegen
Reposted by Cristian Ruiz-Moreno
We identify evidence of off-target probe binding in the 10x Genomics #Xenium v1 Human Breast Gene Expression Panel, compromising the accuracy of resulting #singlecell #spatialtranscriptomics profiles
See our preprint for more details: www.biorxiv.org/content/10.1...
#AcademicSky
🧵👇 1/n
See our preprint for more details: www.biorxiv.org/content/10.1...
#AcademicSky
🧵👇 1/n
Evidence of off-target probe binding in the 10x Genomics Xenium v1 Human Breast Gene Expression Panel compromises accuracy of spatial transcriptomic profiling
The accuracy of spatial gene expression profiles generated by probe-based in situ spatially-resolved transcriptomic technologies depends on the specificity with which probes bind to their intended tar...
www.biorxiv.org
April 3, 2025 at 3:35 PM
We identify evidence of off-target probe binding in the 10x Genomics #Xenium v1 Human Breast Gene Expression Panel, compromising the accuracy of resulting #singlecell #spatialtranscriptomics profiles
See our preprint for more details: www.biorxiv.org/content/10.1...
#AcademicSky
🧵👇 1/n
See our preprint for more details: www.biorxiv.org/content/10.1...
#AcademicSky
🧵👇 1/n