Christopher Southan
@cdsouthan.bsky.social
Joining the dots between chemistry and biology (full profile on LinkedIN)
Gosh, remember those "Mitchell and Moyle" experimental papers well back in day at Dundee
An inspirational example of 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐜𝐫𝐞𝐚𝐭𝐢𝐯𝐢𝐭𝐲, 𝐨𝐫𝐢𝐠𝐢𝐧𝐚𝐥𝐢𝐭𝐲 𝐚𝐧𝐝 𝐫𝐢𝐠𝐨𝐫:
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
November 29, 2025 at 9:29 AM
Gosh, remember those "Mitchell and Moyle" experimental papers well back in day at Dundee
Last #greatcompoundrace of the year. 1) Elsevier | Life Sciences Reaxys stays out in front 2) Suggest CAS harmonise their web instances of different totals 3) Also suggest Royal Society of Chemistry ChemSpider puts total on front page (like it used to be) not just nested under "Promotion
November 25, 2025 at 11:26 AM
Last #greatcompoundrace of the year. 1) Elsevier | Life Sciences Reaxys stays out in front 2) Suggest CAS harmonise their web instances of different totals 3) Also suggest Royal Society of Chemistry ChemSpider puts total on front page (like it used to be) not just nested under "Promotion
Great to attend the ELIXIR-UK All-Hands recently in Exeter and present our UK resource The IUPHAR/BPS Guide to PHARMACOLOGY update lnkd.in/dMUfbbci which was also recently published in the latest NAR Nucleic Acids Research Database Issue (see lnkd.in/dmHapSie)
November 24, 2025 at 5:25 PM
Great to attend the ELIXIR-UK All-Hands recently in Exeter and present our UK resource The IUPHAR/BPS Guide to PHARMACOLOGY update lnkd.in/dMUfbbci which was also recently published in the latest NAR Nucleic Acids Research Database Issue (see lnkd.in/dmHapSie)
Reposted by Christopher Southan
I know some people have had problems accessing the discord servers we use for the UGMs, so I'm trying an experiment with setting up a Zulip server for the #RDKit.
If this works well, we can leave it up as an informal chat/discussion point for the community.
rdkit.zulipchat.com/join/ay4ccup...
If this works well, we can leave it up as an informal chat/discussion point for the community.
rdkit.zulipchat.com/join/ay4ccup...
RDKit
Zulip organization for the RDKit community
rdkit.zulipchat.com
November 6, 2025 at 5:54 AM
I know some people have had problems accessing the discord servers we use for the UGMs, so I'm trying an experiment with setting up a Zulip server for the #RDKit.
If this works well, we can leave it up as an informal chat/discussion point for the community.
rdkit.zulipchat.com/join/ay4ccup...
If this works well, we can leave it up as an informal chat/discussion point for the community.
rdkit.zulipchat.com/join/ay4ccup...
Looks like that top one is not in PubChem yet
November 6, 2025 at 6:31 PM
Looks like that top one is not in PubChem yet
So what was his final score? less than 99 I'm sure....
Breaking news from me this morning: Recursion Pharmaceuticals' Chris Gibson, who promised 100 drugs in 10 years in the early days of the tech-powered company, is stepping down as CEO.
www.statnews.com/2025/11/05/r...
www.statnews.com/2025/11/05/r...
Recursion CEO Chris Gibson out as company head after 12 years
Recursion CEO Chris Gibson is out after 12 years as the ambitious ‘techbio’ company positions itself for its next phase of AI drug discovery.
www.statnews.com
November 5, 2025 at 3:59 PM
So what was his final score? less than 99 I'm sure....
Amen, a PubChem pop takes seconds
October 15, 2025 at 3:21 PM
Amen, a PubChem pop takes seconds
Gosh, will this get me rich?
October 13, 2025 at 7:46 PM
Gosh, will this get me rich?
Looking forward to presenting this on Wed 17 Sept
uchealth.zoom.us/webinar/regi...
uchealth.zoom.us/webinar/regi...
Welcome! You are invited to join a webinar: Synergies between BindingDB and PubChem. After registering, you will receive a confirmation email about joining the webinar.
BindingDB Webinar Sep 2025
uchealth.zoom.us
September 15, 2025 at 12:28 PM
Looking forward to presenting this on Wed 17 Sept
uchealth.zoom.us/webinar/regi...
uchealth.zoom.us/webinar/regi...
Fine, but that seaweed might whiff a bit....
After nineteen years, I am living near the ocean once again, and it feels like the cancellation of a debt
September 3, 2025 at 8:52 PM
Fine, but that seaweed might whiff a bit....
Wow!
Check out our latest paper, a huge effort led by @benjaminguinet.bsky.social and @tvdvalk.bsky.social 🦣🔍🦠
Paper: www.cell.com/cell/abstrac...
Paper: www.cell.com/cell/abstrac...
September 3, 2025 at 4:51 PM
Wow!
But gruniad website still free for now
As a Brit expat in the States, it’s sad to see that access to the BBC News website is now paywalled. $90 a year!
September 1, 2025 at 5:28 PM
But gruniad website still free for now
ACS Washington presentation lnkd.in/dxvaQn9V
A well attended joint CHAL & CINF session and thanks to Emilia Hietala and Collaborative Drug Discovery - CDD Vault
A well attended joint CHAL & CINF session and thanks to Emilia Hietala and Collaborative Drug Discovery - CDD Vault
September 1, 2025 at 2:06 PM
ACS Washington presentation lnkd.in/dxvaQn9V
A well attended joint CHAL & CINF session and thanks to Emilia Hietala and Collaborative Drug Discovery - CDD Vault
A well attended joint CHAL & CINF session and thanks to Emilia Hietala and Collaborative Drug Discovery - CDD Vault
Nice to see a steady engagement increase for my blog lnkd.in/ebDNdfG :)
August 30, 2025 at 9:35 PM
Nice to see a steady engagement increase for my blog lnkd.in/ebDNdfG :)
Pleased to attend American Chemical Society Washington next week with ACS CINF slots for "Update of InChIKey searching in Google" Aug 18 from 3:20 PM and "Mining the outputs of AI drug discovery from patents" August 21 9:05 (a CDD Vault collaboration)
August 13, 2025 at 5:51 PM
Pleased to attend American Chemical Society Washington next week with ACS CINF slots for "Update of InChIKey searching in Google" Aug 18 from 3:20 PM and "Mining the outputs of AI drug discovery from patents" August 21 9:05 (a CDD Vault collaboration)
Good idea mate...
Getting frustrated with the number of resources that disappear, change terms of use, etc. Seems cheeky that people publish in places like NAR Database with an 'open' resource, then flip to closed. Tempted to put together a table of all the NAR DB resources and plot existence/current license....
August 5, 2025 at 9:16 PM
Good idea mate...
Enjoyable break visiting my friend and leading Mosel Winemaker Franz-Peter Schmitz from Römerhof in Riol. Great to catch up on the wine technology, commerce and biochemistry as well as socially. New post pending as a follow on from a past blog
cdsouthan.blogspot.com/2013/06/wine...
cdsouthan.blogspot.com/2013/06/wine...
July 31, 2025 at 2:19 PM
Enjoyable break visiting my friend and leading Mosel Winemaker Franz-Peter Schmitz from Römerhof in Riol. Great to catch up on the wine technology, commerce and biochemistry as well as socially. New post pending as a follow on from a past blog
cdsouthan.blogspot.com/2013/06/wine...
cdsouthan.blogspot.com/2013/06/wine...
Couple of recent posts at cdsouthan.blogspot.com
July 19, 2025 at 4:04 PM
Couple of recent posts at cdsouthan.blogspot.com
Real shame 2c @acs.org capitulate to the MJB (mumbo jumbo brigade)
Cinnamon is proving to be more than just a pantry staple. Enjoy a selection of recent research articles uncovering the spice’s surprising versatility across food, textiles, and sustainable packaging.
Read more on ACS Axial: buff.ly/r31v9fT
Read more on ACS Axial: buff.ly/r31v9fT
Beyond the Spice Rack: Exploring the Functional Power of Cinnamon
Cinnamon is proving to be more than just a pantry staple. Enjoy a selection of recent research articles uncovering the spice’s surprising versatility across food, textiles, and sustainable packaging.
buff.ly
July 3, 2025 at 1:03 PM
Real shame 2c @acs.org capitulate to the MJB (mumbo jumbo brigade)
Good 2c a steady < over the last year but more engagement always welcome :) cdsouthan.blogspot.com
June 29, 2025 at 2:15 PM
Good 2c a steady < over the last year but more engagement always welcome :) cdsouthan.blogspot.com
Refreshing Midsummer's day swim at Naset. Finally warm enough to get to second jetty when it was so cold last month I could only just make the first. We'll see how many weeks it takes to extend my efforts to the third jetty (red on right) and eventually ~550 m to get across the inlet (lower left)
June 21, 2025 at 7:30 PM
Refreshing Midsummer's day swim at Naset. Finally warm enough to get to second jetty when it was so cold last month I could only just make the first. We'll see how many weeks it takes to extend my efforts to the third jetty (red on right) and eventually ~550 m to get across the inlet (lower left)
Last day so please do the same (see LinkedIN posts from me and others for the link)
June 15, 2025 at 11:44 AM
Last day so please do the same (see LinkedIN posts from me and others for the link)
Broken DOI :(
🚀 Our paper on the updated PrankWeb, a web app for protein binding site prediction using P2Rank, is out in
@narjournal.bsky.social. Now with docking integration!
👨💻 Try it: prankweb.cz
📄 Paper: doi.org/10.1093/nar/...
💻 GitHub: github.com/cusbg/prankweb
Developed at @cusbg.bsky.social
@narjournal.bsky.social. Now with docking integration!
👨💻 Try it: prankweb.cz
📄 Paper: doi.org/10.1093/nar/...
💻 GitHub: github.com/cusbg/prankweb
Developed at @cusbg.bsky.social
June 12, 2025 at 3:17 PM
Broken DOI :(