PhD positions available in our group! Please share! www.findaphd.com/phds/project...

Just out: 'Aptamer-based burden biosensors' led by Alice in the lab. Funded by NSF-BBSRC in collaboration with @francolab.bsky.social, we show aptamers cause burden in E.coli. We then develop a burden biosensor for identification of low-burden genetic variants: www.sciencedirect.com/science/arti...

We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...

Thanks @manishmicrobe.bsky.social and @oborkowski.bsky.social for two wonderful days!

Annalise Zouein's main PhD research paper is published today in Trends in Biotech. Building and using repetitive transcription factor-binding arrays to modulate gene regulation in mammalian cells. No RNA, no protein - just DNA doing the work! www.sciencedirect.com/science/arti...

Thrilled I am going to be speaking at the Royal Society Theo Murphy Workshop on Generative Biology next October! royalsociety.org/science-even...

A huge, new resource for plasmid research - PlasmidScope is a database of 852,000 #plasmid sequences with a rich set of annotations, automated online analysis and interactive visualisation academic.oup.com/nar/article/...

Rearranging mammalian genomes with recombinases to study structural variants at scale provides insights into genome organization and dispensability #NBTHighlight
www.science.org/doi/10.1126/... and www.science.org/doi/10.1126/...

Our work on 'Degradation bottlenecks in mammalian cells' is now out @NatureComms:
www.nature.com/articles/s41...

Well done to the whole team! You can read this at rdcu.be/d5o2h
Happy 2025 everyone!

Check out our latest pre-print where we used our ASP-#SPARK #sensor to unveil #SnRK1's multifaceted role during #plant growth and #development! bit.ly/49JVZrY
Including real-time #spatiotemporal visualization of SnRK1 activity in a growing #Arabidopsis root! 😀

Latest preprint from Jane (Xinyu Lu) in our group explores what happens when we build a synthetic genome cluster in yeast for Histidine biosynthesis and SCRaMbLE it to see whether selected-for gene rearrangements can guide better design.

Still time to apply, please share and spread the opportunity!

Great to have @ciaranlkelly.bsky.social presenting the exciting work his group is doing here at Imperial!

NAPIC website is now live!: www.napic.ac.uk

I agree! Nice to find everyone (almost) here!

Grant selection panels: just draw the a dice

Exciting post doc opportunity: we are seeking a post doc to work with us and @ProfTomEllis on large DNA engineering in mammalian cells funded by @ChanZuckerberg.
Come and join us at @ImperialChemEng!
Apply at the link below:
www.imperial.ac.uk/jobs/search-...