Nature Biotechnology
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Multiplexed profiling of transcriptional regulators in plant cells - @ucberkeleyofficial.bsky.social @biosci.lbl.gov go.nature.com/4pw5cL1
Multiplexed profiling of transcriptional regulators in plant cells - Nature Biotechnology
ENTRAP-seq systematically links protein sequence to transcriptional output in a native plant context.
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November 25, 2025 at 3:25 PM
Multiplexed profiling of transcriptional regulators in plant cells - @ucberkeleyofficial.bsky.social @biosci.lbl.gov go.nature.com/4pw5cL1
As pharma ramps up efforts on disorders of aging, a new era of disease prevention comes into focus go.nature.com/49aN7gR
November 25, 2025 at 3:13 PM
As pharma ramps up efforts on disorders of aging, a new era of disease prevention comes into focus go.nature.com/49aN7gR
Biomacromolecules are delivered across the blood–brain barrier when administered systemically go.nature.com/412exBi
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Intravenous administration of blood–brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system - Nature Biotechnology
Biomacromolecules are delivered across the blood–brain barrier when administered systemically.
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November 25, 2025 at 4:23 AM
Biomacromolecules are delivered across the blood–brain barrier when administered systemically go.nature.com/412exBi
rdcu.be/eRyTm
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Recently released guidance on patent applications related to artificial intelligence raises the question of how AI-related inventions are being protected by the patent system in China go.nature.com/43yWi78
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Patenting biopharmaceutical inventions that use artificial intelligence in China - Nature Biotechnology
Recently released guidance on patent applications related to artificial intelligence raises the question of how artificial intelligence-related inventions (for instance, AlphaFold-related inventions) ...
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November 24, 2025 at 11:34 PM
Recently released guidance on patent applications related to artificial intelligence raises the question of how AI-related inventions are being protected by the patent system in China go.nature.com/43yWi78
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This year’s Nobel Prize in Chemistry was awarded for research on metal–organic frameworks, whose nanoscale cavities are being exploited for myriad industrial applications but are also beginning to make progress in the clinic www.nature.com/articles/s41...
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Chemistry Nobel materials in the clinic - Nature Biotechnology
Nature Biotechnology - Chemistry Nobel materials in the clinic
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November 24, 2025 at 5:24 PM
This year’s Nobel Prize in Chemistry was awarded for research on metal–organic frameworks, whose nanoscale cavities are being exploited for myriad industrial applications but are also beginning to make progress in the clinic www.nature.com/articles/s41...
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rdcu.be/eRzse
Career development awards support early-stage researchers in life sciences entrepreneurship go.nature.com/4ob0vVV
Career development awards support early-stage researchers in life sciences entrepreneurship - Nature Biotechnology
The New York University Biomedical Entrepreneurship Educational Program’s career development awards boost early-stage scientists’ business knowledge and acumen to ease their transition from academia t...
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November 24, 2025 at 4:05 PM
Career development awards support early-stage researchers in life sciences entrepreneurship go.nature.com/4ob0vVV
Reposted by Nature Biotechnology
The brief digital edition of Nature Biotechnology November issue is live now! 🎉 Check it out here👉 mp.weixin.qq.com/s/RxFGoMOwgv... @natbiotech.nature.com
November 22, 2025 at 11:59 AM
The brief digital edition of Nature Biotechnology November issue is live now! 🎉 Check it out here👉 mp.weixin.qq.com/s/RxFGoMOwgv... @natbiotech.nature.com
Reposted by Nature Biotechnology
Introducing Foli-seq in @natbiotech.nature.com today. Foli-seq can be used to measure gut-derived RNA from fecal matter (signals of immune, secretory & epithelial cells). We used this to map gut inflammation, drug response, and host-microbe interactions. 💩🧬💊🦠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - Nature Biotechnology
Profiling host RNA shed in feces reveals disease states in the gut.
www.nature.com
November 17, 2025 at 8:55 PM
Introducing Foli-seq in @natbiotech.nature.com today. Foli-seq can be used to measure gut-derived RNA from fecal matter (signals of immune, secretory & epithelial cells). We used this to map gut inflammation, drug response, and host-microbe interactions. 💩🧬💊🦠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Biopharma’s reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence go.nature.com/4r9HhTw
Heart matters: new treatments, tools and access channels - Nature Biotechnology
Biopharma’s reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence.
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November 21, 2025 at 6:55 PM
Biopharma’s reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence go.nature.com/4r9HhTw
Each year, we highlight companies that received sizeable early-stage funding in the previous year. Firefly Bio seeks to improve on antibody–drug conjugates and proteolysis-targeting chimeras by combining them as degrader–antibody conjugates go.nature.com/4ibvobr
Editor’s pick: Firefly Bio - Nature Biotechnology
Each year, Nature Biotechnology highlights companies that received sizeable early-stage funding in the previous year. Firefly Bio seeks to improve on antibody–drug conjugates and proteolysis-targeting...
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November 21, 2025 at 4:39 PM
Each year, we highlight companies that received sizeable early-stage funding in the previous year. Firefly Bio seeks to improve on antibody–drug conjugates and proteolysis-targeting chimeras by combining them as degrader–antibody conjugates go.nature.com/4ibvobr
Programmable initiation of mRNA translation by trans-RNA - @cornelluniversity.bsky.social @iecb.bsky.social go.nature.com/3K7SEdO
Programmable initiation of mRNA translation by trans-RNA - Nature Biotechnology
Translation can be initiated from a specific start codon using trans-RNA.
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November 21, 2025 at 2:44 PM
Programmable initiation of mRNA translation by trans-RNA - @cornelluniversity.bsky.social @iecb.bsky.social go.nature.com/3K7SEdO
The first-in-class small molecule #Jascayd targets a fibrotic signaling cascade, offering new hope in a stagnant therapeutic field, as several other programs near maturity www.nature.com/articles/s41...
FDA approves new mechanism to treat idiopathic pulmonary fibrosis, expanding limited arsenal - Nature Biotechnology
The first-in-class small molecule Jascayd targets a fibrotic signaling cascade, offering new hope in a stagnant therapeutic field, as several other programs near maturity.
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November 21, 2025 at 1:47 PM
The first-in-class small molecule #Jascayd targets a fibrotic signaling cascade, offering new hope in a stagnant therapeutic field, as several other programs near maturity www.nature.com/articles/s41...
A lipid nanoparticle is used to deliver mRNA to hematopoietic stem cells in macaques go.nature.com/3CGO1Dy
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Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys - Nature Biotechnology
A lipid nanoparticle is used to deliver mRNA to hematopoietic stem cells in macaques.
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November 21, 2025 at 2:02 AM
A lipid nanoparticle is used to deliver mRNA to hematopoietic stem cells in macaques go.nature.com/3CGO1Dy
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Need for a shared language and minimum information standards for bioprocess development - @ucl.ac.uk go.nature.com/3X3ZG6q
Need for a shared language and minimum information standards for bioprocess development - Nature Biotechnology
Nature Biotechnology - Need for a shared language and minimum information standards for bioprocess development
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November 20, 2025 at 6:26 PM
Need for a shared language and minimum information standards for bioprocess development - @ucl.ac.uk go.nature.com/3X3ZG6q
In Brief: uniQure's AMT-130, a one-off microRNA gene therapy administered directly into the brain, has met its primary endpoint in a phase 1/2 study, slowing Huntington disease progression by 75% nature.com/articles/s41...
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Artificial miRNA slows Huntington’s - Nature Biotechnology
Nature Biotechnology - Artificial miRNA slows Huntington’s
nature.com
November 20, 2025 at 6:21 PM
In Brief: uniQure's AMT-130, a one-off microRNA gene therapy administered directly into the brain, has met its primary endpoint in a phase 1/2 study, slowing Huntington disease progression by 75% nature.com/articles/s41...
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rdcu.be/ePM4Y
A compound that enhances homology-directed repair in CRISPR editing leads to genome instability go.nature.com/3D2e4Fh
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Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations - Nature Biotechnology
A compound that enhances homology-directed repair in CRISPR editing leads to genome instability.
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November 20, 2025 at 2:00 AM
A compound that enhances homology-directed repair in CRISPR editing leads to genome instability go.nature.com/3D2e4Fh
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Chemistry Nobel materials in the clinic www.nature.com/articles/s41...
Chemistry Nobel materials in the clinic - Nature Biotechnology
Nature Biotechnology - Chemistry Nobel materials in the clinic
www.nature.com
November 19, 2025 at 9:06 PM
Chemistry Nobel materials in the clinic www.nature.com/articles/s41...
Heart matters: new treatments, tools and access channels go.nature.com/4r9HhTw
Heart matters: new treatments, tools and access channels - Nature Biotechnology
Biopharma’s reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence.
go.nature.com
November 19, 2025 at 3:13 PM
Heart matters: new treatments, tools and access channels go.nature.com/4r9HhTw
Protein degradation is targeted to disease sites using engineered platelets go.nature.com/4fVPgxs
rdcu.be/eQpTw
rdcu.be/eQpTw
Engineered platelets as targeted protein degraders and application to breast cancer models - Nature Biotechnology
Protein degradation is targeted to disease sites using engineered platelets.
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November 19, 2025 at 1:19 PM
Protein degradation is targeted to disease sites using engineered platelets go.nature.com/4fVPgxs
rdcu.be/eQpTw
rdcu.be/eQpTw
FDA approves new mechanism to treat idiopathic pulmonary fibrosis, expanding limited arsenal www.nature.com/articles/s41...
FDA approves new mechanism to treat idiopathic pulmonary fibrosis, expanding limited arsenal - Nature Biotechnology
The first-in-class small molecule Jascayd targets a fibrotic signaling cascade, offering new hope in a stagnant therapeutic field, as several other programs near maturity.
www.nature.com
November 18, 2025 at 10:09 PM
FDA approves new mechanism to treat idiopathic pulmonary fibrosis, expanding limited arsenal www.nature.com/articles/s41...
Each year, we highlight companies that received sizeable early-stage funding in the previous year. Red Queen Therapeutics is combating infectious diseases with peptide viral fusion inhibitors go.nature.com/4r5k0C9
Editor’s pick: Red Queen Therapeutics - Nature Biotechnology
Each year, Nature Biotechnology highlights companies that received sizeable early-stage funding in the previous year. Red Queen Therapeutics is combating infectious diseases with peptide viral fusion ...
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November 18, 2025 at 3:36 PM
Each year, we highlight companies that received sizeable early-stage funding in the previous year. Red Queen Therapeutics is combating infectious diseases with peptide viral fusion inhibitors go.nature.com/4r5k0C9
Generative artificial intelligence is used to design an effective treatment for inflammatory bowel disease in preclinical models go.nature.com/4iteK6Z
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Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitor - Nature Biotechnology
Generative artificial intelligence is used to design an effective treatment for inflammatory bowel disease in preclinical models.
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November 18, 2025 at 4:37 AM
Generative artificial intelligence is used to design an effective treatment for inflammatory bowel disease in preclinical models go.nature.com/4iteK6Z
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Patenting biopharmaceutical inventions that use artificial intelligence in China go.nature.com/43yWi78
November 17, 2025 at 7:00 PM
Patenting biopharmaceutical inventions that use artificial intelligence in China go.nature.com/43yWi78
In Brief: @amgen.bsky.social and @astra-zeneca.bsky.social's #Tezspire (tezepelumab), a monoclonal antibody with a new mechanism of action, gets the go-ahead from US and EU regulators for treating chronic rhinosinusitis with nasal polyps nature.com/articles/s41...
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Chronic nasal congestion gets new treatment - Nature Biotechnology
Nature Biotechnology - Chronic nasal congestion gets new treatment
nature.com
November 17, 2025 at 5:35 PM
In Brief: @amgen.bsky.social and @astra-zeneca.bsky.social's #Tezspire (tezepelumab), a monoclonal antibody with a new mechanism of action, gets the go-ahead from US and EU regulators for treating chronic rhinosinusitis with nasal polyps nature.com/articles/s41...
rdcu.be/ePHg6
rdcu.be/ePHg6
Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - @harriswang.bsky.social go.nature.com/4i7XnZR
Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - Nature Biotechnology
Profiling host RNA shed in feces reveals disease states in the gut.
go.nature.com
November 17, 2025 at 4:30 PM
Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - @harriswang.bsky.social go.nature.com/4i7XnZR