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Nature Biotechnology
@natbiotech.nature.com
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Publishing the best of biotech science and business. Find us on Twitter, Facebook & Instagram. Part of @natureportfolio.nature.com‬.
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Nature Biotechnology @natbiotech.nature.com · 2h
Generative AI surpasses nature in designing proteins for genome editing #NBTintheNews bioengineer.org/generative-a...
Generative AI Surpasses Nature in Designing Proteins for Genome Editing
In an extraordinary leap forward for the field of genetic engineering, researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life
bioengineer.org
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 3h
Genome-edited farm animals from haploid stem cells #NBTNV go.nature.com/4mR49nv
Genome-edited farm animals from haploid stem cells - Nature Biotechnology
Spermatid-like haploid stem cells produce genome-edited farm animals in one generation.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 3h
Site-specific and efficient RNA editing is achieved with a CasRx editor go.nature.com/4dFun7P
rdcu.be/eJI3u
A circularly permuted CasRx platform for efficient, site-specific RNA editing - Nature Biotechnology
Site-specific and efficient RNA editing is achieved with a CasRx editor.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 22h
From cancer to Alzheimer’s: decoding RNA-protein signals #NBTintheNews neurosciencenews.com/rna-mapping-...
From Cancer to Alzheimer’s: Decoding RNA-Protein Signals - Neuroscience News
Scientists have created a breakthrough technology that reveals the entire network of RNA-protein interactions in human cells, offering new insights into how diseases develop.
neurosciencenews.com
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 1d
USC Stem Cell-led study generates authentic embryonic stem cell from birds #NBTintheNews stemcell.keck.usc.edu/study-genera...
USC Stem Cell-led study generates authentic embryonic stem cell from birds
Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg...
stemcell.keck.usc.edu
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 1d
Folding-mediated secretion of pure bispecific antibodies go.nature.com/48NEM2o
Folding-mediated secretion of pure bispecific antibodies - Nature Biotechnology
Mutation of conserved prolines enhances correct pairing of light and heavy chains for bispecific IgG-like antibody production.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 1d
Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells go.nature.com/42wdD05
Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells - Nature Biotechnology
Haploid embryonic stem cells for cattle and sheep are produced, opening new reproductive possibilities.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 1d
Generative AI pushes gene editing beyond nature’s limits #NBTintheNews firstwordpharma.com/story/6241404
firstwordpharma.com
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 1d
Mapping RNA-protein ‘chats’ could uncover new treatments for cancer and brain disease #NBTintheNews today.ucsd.edu/story/mappin...
Mapping RNA-Protein ‘Chats’ Could Uncover New Treatments for Cancer and Brain Disease
A technology that maps entire networks of RNA-protein interactions inside human cells could offer new strategies for treating diseases ranging from cancer to Alzheimer's.
today.ucsd.edu
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 1d
Avian embryonic stem cells derived using egg yolk-based culture #NBTintheNews www.genengnews.com/topics/trans...
Avian Embryonic Stem Cells Derived Using Egg Yolk-Based Culture
Researchers generate authentic embryonic stem cells from birds using an egg yolk-based culture along with a few other key factors.
www.genengnews.com
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 2d
Generative AI is more efficient than nature at designing proteins to edit the genome #NBTintheNews integra-tx.com/generative-a...
AI is more efficient than nature at designing proteins to edit genome
This work led by Integra Therapeutics, a global pioneer published today in the journal "Nature Biotechnology".
integra-tx.com
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Reposted by Nature Biotechnology
delafuentelab.bsky.social
César de la Fuente @delafuentelab.bsky.social · 5d
Thank you so much for highlighting our latest work!
natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 8d
Research Highlight: Mining archaea for antibiotics www.nature.com/articles/s41...
Mining archaea for antibiotics - Nature Biotechnology
Nature Biotechnology - Mining archaea for antibiotics
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Reposted by Nature Biotechnology
biodimi.bsky.social
Dimitrije @biodimi.bsky.social · 6d
Check out our latest work on the discovery and engineering of PiggyBac transposases! 🧵
natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 6d
Discovery and protein language model-guided design of hyperactive transposases - @marcguellc.bsky.social @upf.edu @icreacommunity.bsky.social @crg.eu go.nature.com/4gXLGEw
Discovery and protein language model-guided design of hyperactive transposases - Nature Biotechnology
Phylogenetic mining and protein language models uncover improved PiggyBac transposase sequences.
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Reposted by Nature Biotechnology
upf.edu
Universitat Pompeu Fabra @upf.edu · 6d
#Recerca

Ja és possible dissenyar proteïnes completament sintètiques amb #IA per editar el genoma

Nou estudi d’Integra Therapeutics, el Laboratori de Biologia Sintètica @marcguellc.bsky.social, i el Grup de Disseny de Proteïnes amb IA del @crg.eu, publicat a @natbiotech.nature.com

tuit.cat/d0olZ
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 4d
The COP16 decision established a multilateral mechanism for digital sequence information benefit-sharing. DSI researchers assess what has been accomplished so far and identify remaining challenges go.nature.com/4nBE4t8
rdcu.be/eJnid
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 5d
October 10- Deadline to submit abstracts and grab an early bird registration for our event on nucleic acid medicine with these experts. Learn more> go.nature.com/4mhVASr
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 5d
Behind the paper: Connecting siloed high-content screens communities.springernature.com/posts/connec...
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Nature Biotechnology @natbiotech.nature.com · 5d
Combining expansion microscopy with super-resolution radial fluctuations captures the morphology of single proteins go.nature.com/3Y1FD8M
rdcu.be/eI29D
One-step nanoscale expansion microscopy reveals individual protein shapes - Nature Biotechnology
Combining expansion microscopy with super-resolution radial fluctuations captures the morphology of single proteins.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 6d
Embryonic stem cells across bird species #NBTNV go.nature.com/4ntGnih
Embryonic stem cells across bird species - Nature Biotechnology
A method to produce embryonic stem cells for a range of bird species opens up opportunities in agriculture, developmental biology and species conservation.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 6d
A trimodal protein language model enables advanced protein searches go.nature.com/4pSGJRf
A trimodal protein language model enables advanced protein searches - Nature Biotechnology
A protein foundation model represents protein sequence, structure and function.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 6d
Discovery and protein language model-guided design of hyperactive transposases - @marcguellc.bsky.social @upf.edu @icreacommunity.bsky.social @crg.eu go.nature.com/4gXLGEw
Discovery and protein language model-guided design of hyperactive transposases - Nature Biotechnology
Phylogenetic mining and protein language models uncover improved PiggyBac transposase sequences.
go.nature.com
1 7 14
natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 6d
Improved effectors for CRISPRi/CRISPRa are developed following high-throughput screening of transcriptional domains go.nature.com/3NMu00N
rdcu.be/eI28L
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts - Nature Biotechnology
Improved effectors for CRISPRi/CRISPRa are developed following high-throughput screening of transcriptional domains.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 7d
Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates go.nature.com/46uDMyK
Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates - Nature Biotechnology
Sustained epigenetic silencing in monkeys is made more efficient with optimized regulators.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 7d
Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk
Scaling DNA synthesis with a microchip-based massively parallel synthesis system - Nature Biotechnology
A microchip-based DNA synthesis method enables scalable production of complex DNA constructs.
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 7d
Detecting and quantifying circular RNAs in terabyte-scale RNA-seq datasets with CIRI3 go.nature.com/42jUdLK
Detecting and quantifying circular RNAs in terabyte-scale RNA-seq datasets with CIRI3 - Nature Biotechnology
CIRI3 speeds up circRNA detection with low memory requirements.
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