Nature Biotechnology
@natbiotech.nature.com
Publishing the best of biotech science and business. Find us on Twitter, Facebook & Instagram. Part of @natureportfolio.nature.com.
Developers have married gene-modulating oligonucleotides with the targeted precision of antibodies, and the first filings using such conjugates in Duchenne muscular dystrophy are imminent www.nature.com/articles/s41...
January 12, 2026 at 6:07 PM
Developers have married gene-modulating oligonucleotides with the targeted precision of antibodies, and the first filings using such conjugates in Duchenne muscular dystrophy are imminent www.nature.com/articles/s41...
Targeted delivery of genome editors in vivo - @doudna-lab.bsky.social @innovativegenomics.bsky.social go.nature.com/4qKp6Tb
January 12, 2026 at 5:35 PM
Targeted delivery of genome editors in vivo - @doudna-lab.bsky.social @innovativegenomics.bsky.social go.nature.com/4qKp6Tb
Now with oligos: antibody–oligonucleotide conjugates are the new drug modality to watch doi.org/10.1038/s415...
January 8, 2026 at 3:05 PM
Now with oligos: antibody–oligonucleotide conjugates are the new drug modality to watch doi.org/10.1038/s415...
Balancing immunity with Tregs go.nature.com/4qNezXD
January 7, 2026 at 2:29 PM
Balancing immunity with Tregs go.nature.com/4qNezXD
This year’s most popular stories are a testament to biotech ingenuity and a cause for celebration: the gene editing triumph that cured ‘baby KJ’ of a rare genetic disorder in record time; the bispecific molecules that trick HIV out of cells to destroy them... nature.com/articles/s41...
rdcu.be/eWPsd
rdcu.be/eWPsd
December 29, 2025 at 10:02 PM
This year’s most popular stories are a testament to biotech ingenuity and a cause for celebration: the gene editing triumph that cured ‘baby KJ’ of a rare genetic disorder in record time; the bispecific molecules that trick HIV out of cells to destroy them... nature.com/articles/s41...
rdcu.be/eWPsd
rdcu.be/eWPsd
This year, biotechnology was characterized by accelerated convergence between gene editing, cell and gene therapy, immunotherapy, and AI. CRISPR-based editing tools are more precise and clinically relevant, and biotech continues to push the boundaries of immunotherapy go.nature.com/4oCK84L
December 29, 2025 at 7:21 PM
This year, biotechnology was characterized by accelerated convergence between gene editing, cell and gene therapy, immunotherapy, and AI. CRISPR-based editing tools are more precise and clinically relevant, and biotech continues to push the boundaries of immunotherapy go.nature.com/4oCK84L
Our editors pick their favorite research articles from 2025 go.nature.com/4oCK84L
December 12, 2025 at 5:21 PM
Our editors pick their favorite research articles from 2025 go.nature.com/4oCK84L
The December issue is live nature.com/nbt/volumes/...
Hybrid quantum computing for drug design. Ghazi Vakili et al. present a hybrid quantum–classical generative model to design molecules to inhibit KRAS activity. Two candidates are synthesized and further characterized go.nature.com/3EitbLm
Hybrid quantum computing for drug design. Ghazi Vakili et al. present a hybrid quantum–classical generative model to design molecules to inhibit KRAS activity. Two candidates are synthesized and further characterized go.nature.com/3EitbLm
December 12, 2025 at 3:09 PM
The December issue is live nature.com/nbt/volumes/...
Hybrid quantum computing for drug design. Ghazi Vakili et al. present a hybrid quantum–classical generative model to design molecules to inhibit KRAS activity. Two candidates are synthesized and further characterized go.nature.com/3EitbLm
Hybrid quantum computing for drug design. Ghazi Vakili et al. present a hybrid quantum–classical generative model to design molecules to inhibit KRAS activity. Two candidates are synthesized and further characterized go.nature.com/3EitbLm
2025: research in review go.nature.com/4oCK84L
December 8, 2025 at 7:47 PM
2025: research in review go.nature.com/4oCK84L
Beyond the unprecedented efficacy of GLP-1s in obesity and type 2 diabetes, evidence that they improve comorbidities has been accumulating at an impressive pace in recent years go.nature.com/49aN7gR
December 3, 2025 at 2:11 PM
Beyond the unprecedented efficacy of GLP-1s in obesity and type 2 diabetes, evidence that they improve comorbidities has been accumulating at an impressive pace in recent years go.nature.com/49aN7gR
As pharma ramps up efforts on disorders of aging, a new era of disease prevention comes into focus go.nature.com/49aN7gR
November 25, 2025 at 3:13 PM
As pharma ramps up efforts on disorders of aging, a new era of disease prevention comes into focus go.nature.com/49aN7gR
Patenting biopharmaceutical inventions that use artificial intelligence in China go.nature.com/43yWi78
November 17, 2025 at 7:00 PM
Patenting biopharmaceutical inventions that use artificial intelligence in China go.nature.com/43yWi78
Are GLP-1s the first longevity drugs? go.nature.com/49aN7gR
November 12, 2025 at 8:42 PM
Are GLP-1s the first longevity drugs? go.nature.com/49aN7gR
The November issue is live nature.com/nbt/volumes/...
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
November 12, 2025 at 7:03 PM
The November issue is live nature.com/nbt/volumes/...
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
While medical digital twins hold great promise for personalized healthcare—with promising applications in oncology, diabetes management and cardiovascular medicine—their implementation is no easy feat. We asked experts in the field for their thoughts go.nature.com/42YcE9c
rdcu.be/eOir8
rdcu.be/eOir8
November 4, 2025 at 9:30 PM
While medical digital twins hold great promise for personalized healthcare—with promising applications in oncology, diabetes management and cardiovascular medicine—their implementation is no easy feat. We asked experts in the field for their thoughts go.nature.com/42YcE9c
rdcu.be/eOir8
rdcu.be/eOir8
New approaches to engineering plant immunity can more broadly protect crops against pathogens and disease, once they get through regulatory hurdles go.nature.com/475WgV7
rdcu.be/eN6q4
rdcu.be/eN6q4
November 3, 2025 at 9:02 PM
New approaches to engineering plant immunity can more broadly protect crops against pathogens and disease, once they get through regulatory hurdles go.nature.com/475WgV7
rdcu.be/eN6q4
rdcu.be/eN6q4
How AI is supercharging antibiotic discovery #NBTintheNews www.gene.com/stories/how-...
October 30, 2025 at 8:14 PM
How AI is supercharging antibiotic discovery #NBTintheNews www.gene.com/stories/how-...
Applications of digital twins in medicine go.nature.com/42YcE9c
October 24, 2025 at 1:30 PM
Applications of digital twins in medicine go.nature.com/42YcE9c
Vicković Lab publishes a new study on colon aging #NBTintheNews via @cancerdynamics.bsky.social cancerdynamics.columbia.edu/news/vickovi...
October 23, 2025 at 9:22 PM
Vicković Lab publishes a new study on colon aging #NBTintheNews via @cancerdynamics.bsky.social cancerdynamics.columbia.edu/news/vickovi...
After an evaluation of various technologies, long-read whole-genome sequencing is at present the only reliable approach to confirm the absence of foreign DNA in genome-edited crops go.nature.com/3WbbKlW
rdcu.be/eMdWr
rdcu.be/eMdWr
October 22, 2025 at 6:08 PM
After an evaluation of various technologies, long-read whole-genome sequencing is at present the only reliable approach to confirm the absence of foreign DNA in genome-edited crops go.nature.com/3WbbKlW
rdcu.be/eMdWr
rdcu.be/eMdWr
Rewriting the code of plant immunity go.nature.com/475WgV7
October 14, 2025 at 8:25 PM
Rewriting the code of plant immunity go.nature.com/475WgV7
The October issue is live nature.com/nbt/volumes/...
The cover shows perturbations that convert stem-like, atypical teratoid rhabdoid tumor (AT/RT) cells into a more differentiated, neuron-like state go.nature.com/4hXER5O
The cover shows perturbations that convert stem-like, atypical teratoid rhabdoid tumor (AT/RT) cells into a more differentiated, neuron-like state go.nature.com/4hXER5O
October 14, 2025 at 4:12 PM
The October issue is live nature.com/nbt/volumes/...
The cover shows perturbations that convert stem-like, atypical teratoid rhabdoid tumor (AT/RT) cells into a more differentiated, neuron-like state go.nature.com/4hXER5O
The cover shows perturbations that convert stem-like, atypical teratoid rhabdoid tumor (AT/RT) cells into a more differentiated, neuron-like state go.nature.com/4hXER5O
Programmable promoter editing for precise control of transgene expression - @mitcheme.bsky.social @mitdeptofbe.bsky.social go.nature.com/4h9wlR1
October 13, 2025 at 7:11 PM
Programmable promoter editing for precise control of transgene expression - @mitcheme.bsky.social @mitdeptofbe.bsky.social go.nature.com/4h9wlR1
Engineered pattern recognition receptors enhance broad-spectrum plant resistance - @zmbp-tuebingen.bsky.social go.nature.com/474nnA9
October 13, 2025 at 6:59 PM
Engineered pattern recognition receptors enhance broad-spectrum plant resistance - @zmbp-tuebingen.bsky.social go.nature.com/474nnA9
The COP16 decision established a multilateral mechanism for digital sequence information benefit-sharing. DSI researchers assess what has been accomplished so far and identify remaining challenges go.nature.com/4nBE4t8
rdcu.be/eJnid
rdcu.be/eJnid
October 3, 2025 at 8:08 PM
The COP16 decision established a multilateral mechanism for digital sequence information benefit-sharing. DSI researchers assess what has been accomplished so far and identify remaining challenges go.nature.com/4nBE4t8
rdcu.be/eJnid
rdcu.be/eJnid