🧠 New preprint 🧠
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151

⭐New preprint: "A multiscale theory for network advection-reaction-diffusion"

with @alaingoriely.bsky.social and Emilia Cozzolino

arxiv.org/abs/2509.06546

Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease: royalsocietypublishing.org/doi/10.1098/... #ProcA #Alzheimers #biophysics

In this paper, we connect local damage to brain vasculature to global progression of toxic proteins leading to neurodegenerative diseases.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.