Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide

www.nature.com/articles/s41...

Beautiful work on the emergence of the pandemic clone of V. parahaemolyticus

Our “Less is more” story is out! 🚀 We reveal how gene loss shaped the adaptive evolution of pandemic Vibrio parahaemolyticus, highlight a potentially general mechanism across bacteria. Huge thanks @danielfalush.bsky.social @campy-bara.bsky.social @jaimemurtaza.bsky.social & all coauthors

How to get introgressed fragments in genomic data? Everything you always wanted to know you find in our review in @cp-trendsgenetics.bsky.social, led by Xin Huang:
doi.org/10.1016/j.ti...

Figure 4. Evolutionary dynamics and global dissemination of the MR-MT28 clone

Figure 3. Temporal dynamics of B. pertussis lineages (A), macrolide resistance (B), and antigenic (C) profiles

Figure 2. Global population structure and resistance and antigenic profiles of B. pertussis

Figure 1. Global pertussis case numbers and incidence rates since 2000

What drove the post-pandemic global pertussis upsurge? Immunity debt? Waning immunity? Other factors?
Our recent study highlights the key role of pathogen evolution.
We also identified the global spread of a drug-resistant clone, MR-MT28, which warrants coordinated global surveillance.

Molassodon! Excited to post my research group's first laboratory project. We identify a phenotype and a putative ecological strategy for the Molassodon ecospecies of Vibrio parahamolyticus, thanks to the hard work of our lab team led by @campy-bara.bsky.social www.biorxiv.org/content/10.1...

Delighted to present our Macrogenetics atlas of prokaryotes. www.biorxiv.org/content/10.1... This is a herculean effort from Chao Yang, which has a previous existence as a preprint first posted in 2018 "why panmictic bacteria are rare?" www.biorxiv.org/content/10.1...