𝙲𝚑𝚊𝚛𝚕𝚎𝚜 𝙲. 𝙼𝚊𝚗𝚗
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charlescmann.bsky.social
𝙲𝚑𝚊𝚛𝚕𝚎𝚜 𝙲. 𝙼𝚊𝚗𝚗
@charlescmann.bsky.social
Author of "1491, "1493," and, most recently, "The Wizard and the Prophet." New book coming out in Spring 2027 from Knopf.

The background image is real old by now, but I like the pig. The avatar photo is only a few years old, though, so that's something.
Thanks--the whole story is extraordinarily interesting.
January 12, 2026 at 4:28 PM
Reposted by 𝙲𝚑𝚊𝚛𝚕𝚎𝚜 𝙲. 𝙼𝚊𝚗𝚗
the short-term potency of the kinepox inoculations (which were made up of ground up scabs from persons infected with cowpox) meant there was a whole global network of infected cowpox patients used for this purpose, who were shipped all over the globe

www.theatlantic.com/science/arch...
22 Orphans Gave Up Everything to Distribute the World’s First Vaccine
Spain’s strategy for rolling out the smallpox vaccine ran into some very 19th-century problems.
www.theatlantic.com
January 12, 2026 at 4:21 PM
...profoundly important this very smart man viewed vaccination. It is extraordinary to consider that RFK Jr. is turning the nation away from something that literally inspired its founders.
January 12, 2026 at 4:18 PM
...and considered it such a priceless gift that it should be shared even with people he saw mainly as rivals and potential enemies. As it happened, the hard conditions of the journey made the "kinepox" samples lose their efficacy, so Jefferson's plans didn't work out. But it gives a hint of how...
Inoculation
Learn more about Thomas Jefferson's interest in early vaccinations and his efforts to inoculate his family and members of the Monticello enslaved community against smallpox.
www.monticello.org
January 12, 2026 at 4:16 PM
That far cliff is Mexico--this is the Rio Grande river. Talk about a border wall.
January 6, 2026 at 11:56 PM
Oh yes. Suddenly the clouds parted and this golden light poured onto the dark red road. It was incredible. I understood exactly what Judd saw.
January 5, 2026 at 4:55 PM
As someone with a brother and a nephew living in Brooklyn, I approve.
January 2, 2026 at 10:14 PM
Oh, sure, Grand Canyon is bigger. But Palo Duro is amazing. Everything about it, maybe especially its history with the Comanche, is very cool.
January 2, 2026 at 4:00 PM
Lots of cool birds that I wasn't knowledgeable enough to identify.
January 2, 2026 at 3:27 PM
Err, "national park."
January 2, 2026 at 3:10 PM
My wife said I should explain Palo Duro, because it's inexplicably little-known. Palo Duro, the second biggest canyon in North America, is much like Grand Canyon, except nobody has heard of it and it's a Texas state park and not a natural park.
January 2, 2026 at 3:08 PM