cklein
christophklein.bsky.social
cklein
@christophklein.bsky.social
Reposted by cklein
insitro is proud to welcome Stephen Hitchcock (ex-Takeda CSO) and Vijay Pande (VZVC co-founder, formerly on our Board) as scientific advisors, focused on translating AI-predicted targets into clinical drug candidates through our ChemML platform. www.insitro.com/news/insitro...
December 3, 2025 at 3:43 PM
Reposted by cklein
We’re excited to share a new article from @insitro.bsky.social (first author @zmccaw.bsky.social) in @ajhgnews.bsky.social, introducing a summary-statistic-based implementation of the COding-variant Allelic Series Test, COAST-SS: www.sciencedirect.com/science/arti...
A scalable framework for identifying allelic series from summary statistics
Genes where a dose-response relationship exists between functionality and phenotypic impact are appealing therapeutic targets, as the effects of pharm…
www.sciencedirect.com
October 18, 2025 at 11:53 AM