Francesca Ciccarelli
@ciccarellilab.bsky.social
540 followers 390 following 48 posts
We study the drivers of cancer evolution from initiation to response to therapy. We are part of the Centre for Cancer Evolution at Barts Cancer Institute and the Francis Crick Institute in London, UK. Posts from Francesca
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ciccarellilab.bsky.social
😂 its more rock’n’roll though 😂
ciccarellilab.bsky.social
First time I give a talk literally in a football stadium 😎⚽️
ciccarellilab.bsky.social
Our first Centre for Cancer Evolution PI retreat! A wonderful day at Goodenough House discussing science, strategy and forging new collaborations @qmbci.bsky.social
ciccarellilab.bsky.social
Great science and good fun at the faculty retreat of the Centre for Cancer Evolution @qmbci.bsky.social. Here @stuartmcdonald.bsky.social explaining his big question!
ciccarellilab.bsky.social
Appennine mountains in Abruzzo, central Italy. Highly recommended
ciccarellilab.bsky.social
This is an important milestone: mutagenic drugs can increase TMB and induce a dMMR-like genetic profile, but do not improve response to immunotherapy in pMMR CRC patients. Some evidence of TIME remodelling, but likely not in the direction needed fro response... www.sciencedirect.com/science/arti...
Induction of a mismatch repair deficient genotype by tailored chemical mutagenesis in experimental models of cancer
Mismatch repair deficient (MMRd) tumors harbor thousands of somatic mutations enriched for insertion–deletion (indels) conferring high sensitivity to …
www.sciencedirect.com
ciccarellilab.bsky.social
Great meeting and great questions! Thanks for inviting me!
cruk-si.bsky.social
Francesca Ciccarelli @ciccarellilab.bsky.social is up next to tell us about spatial drivers of response to immunotherapy in colon cancer

Thank you to TransnetYX for sponsoring Francesca’s talk!

@qmbci.bsky.social | @crick.ac.uk | @cruk-cityoflondon.bsky.social | #BICC2025
ciccarellilab.bsky.social
Our very own @mirjana-efremova.bsky.social (very small compared to the very huge screen) speaking about her beautiful data on cell plasticity in cancer mets at the #Beatson International Cancer Conference. @qmbci.bsky.social @cruk-mi.bsky.social
ciccarellilab.bsky.social
La Caixa panel dinners are always a treat! View of Barcelona from the museum of Catalan art
ciccarellilab.bsky.social
I spent two days meeting students and faculty & delivering the keynote speech at the London Health Research Day @westernu.bsky.social. I truly enjoyed the enthusiasm and genuine engagements of the young generation of cancer researchers! Thanks @ggloor.bsky.social & colleagues for inviting me!
ciccarellilab.bsky.social
Street crossing in London, ON 🦆🦆🦆
ciccarellilab.bsky.social
Thanks for inviting. It was fun!
ciccarellilab.bsky.social
Familiar faces in Belfast! Enjoyable time at the meeting of the Irish Association for Cancer Research! @qmbci.bsky.social
ciccarellilab.bsky.social
Next Thu 13th March Ilaria Malanchi @ila07.bsky.social and I will host the next "Medicine at the Crick" event focusing on how tissues evolve over time and why this may initiate disease. Free in person/virtual registration @crick.ac.uk: www.eventbrite.co.uk/e/medicine-a...
Reposted by Francesca Ciccarelli
donald-tusk.bsky.social
Dear Volodymyr Zelenskyy, dear Ukrainian friends, you are not alone.
ciccarellilab.bsky.social
We have two open positions for #computationalbiologists to work on:
1. Early cancer initiation following our work in #NatureCancer (Ref 5028)
2. Response to cancer immunotherapy following our work in #CancerCell (Ref 5073)
To apply use the provided reference numbers: www.qmul.ac.uk/jobs/vacanci...
ciccarellilab.bsky.social
Beautiful cover 😍 from an idea of our own @pedrandrei.bsky.social! Credits to Joe Brock from @crick.ac.uk
cp-cancercell.bsky.social
The February issue of Cancer Cell is fresh off the press! You can read it now: www.cell.com/cancer-cell/...
ciccarellilab.bsky.social
Very timely publication on World Cancer Day and spot on title considering the times we live in. I am very proud of all wonderful colleagues that dedicate their talent to understand, treat and eventually cure cancer @qmbci.bsky.social 💪💪💪
Reposted by Francesca Ciccarelli
lambalastair.bsky.social
Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer

Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch

@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Reposted by Francesca Ciccarelli
lambalastair.bsky.social
Cool to be at #FoG2025 @fogenomics.bsky.social

A bit more #SpatialGenomics content this year which is great!

Surprise visit from #Darth & #Chewbacca!

@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social