Chinese Journal of Natural Medicines
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Chinese Journal of Natural Medicines
@cjnm05.bsky.social
CJNM is devoted to communicating among pharmaceutical and medicinal plant scientists to advance research in natural medicines and traditional Chinese medicines.
🧬🌿 Can natural medicines rejuvenate stem cells?
A CJNM review shows that MSC senescence, a key challenge in regenerative medicine, may be delayed by Chinese herbal medicines and natural compounds.
🔗Read on ScienceDirect
#CJNM #StemCells #RegenerativeMedicine #NaturalProducts
Effect and mechanism of Chinese medicine on inhibiting the senescence of mesenchymal stem cells
Mesenchymal stem cells (MSCs) are pluripotent stem cells isolated from human tissues. Due to their strong self-renewal capacity, pluripotency, and imm…
www.sciencedirect.com
February 6, 2026 at 1:35 PM
🧠🌿 Neuroprotection from nature
CJNM reports Atractylodimers A–D, unprecedented sesquiterpenoid dimers from Atractylodes macrocephala. Compounds 1–2 show significant neuroprotective activity in PC12 cells, suggesting potential for neurotherapeutic research.

#CJNM #Neuroprotection #NaturalProducts
Atractylodimers A−D, unprecedented sesquiterpenoid dimers with cage-like skeletons from Atractylodes macrocephala and their neuroprotective activities
Atractylodimers A−D (1−4), sesquiterpenoid dimers (SDs) featuring a unique cage-like structure, were isolated from the rhizomes of Atractylodes macroc…
www.sciencedirect.com
February 5, 2026 at 2:08 PM
⚗️ New strategies in halogenated natural products!
CJNM reports a method to incorporate F, Cl, Br, and I into C-ring-cleaved angucyclinones, efficiently producing bioactive molecules for cancer research.

🔗 Read on ScienceDirect!

#CJNM #Biosynthesis #HalogenatedNaturalProducts #CancerResearch
Generation of halogenated angucyclinones with cytotoxicity activities against human cancer cell lines based on biosynthesis and chemical conversion
Halogen substituents play a crucial role in the structural diversity and biological activity of natural products, and the synthesis of halogenated mol…
www.sciencedirect.com
February 4, 2026 at 2:44 PM
🫁 How does S1 act against allergic asthma?

A #CJNM study shows that this phenolic acid from Salvia miltiorrhiza suppresses mast cell activation and rebalances Th17/Treg via TLR4 signaling.

Natural products still have a lot to offer 🌿
🔗 Read full article

#Asthma #Inflammation #cjnm
A new phenolic acid isolated from Salvia miltiorrhiza ameliorates OVA-induced allergic asthma by regulation of Th17/Treg cells and inflammation through the TLR4 pathway
Salvia miltiorrhiza (S. miltiorrhiza) represents a crucial component of traditional Chinese medicine, demonstrating effects on blood circulation activ…
www.sciencedirect.com
February 2, 2026 at 1:28 PM
Bioactive treasures from the sea 🌊🌿

A #CJNM study reports ircinrimane-type sesquiterpenoids from marine sponges with cytotoxic and anti-inflammatory activity, highlighting marine natural products as a rich source of novel bioactive scaffolds.

🔗 Read on ScienceDirect

#MarineNaturalProducts #CJNM
Ircinrimanes A−J: ten undescribed rearranged 4,9-friedodrimane merosesquiterpenoids with cytotoxic and anti-inflammatory activities from the marine sponge Ircinia sp
Ten previously undescribed rearranged 4,9-friedodrimane merosesquiterpenoids, designated ircinrimanes A−J (1−10), were isolated from the marine sponge…
www.sciencedirect.com
January 29, 2026 at 2:12 PM
🌿 Corilagin & Acute Lung Injury

A new #CJNM study shows that corilagin reduces lung inflammation by inhibiting RIPK1/RIPK3/MLKL-mediated necroptosis and restoring mitochondrial integrity in mouse models.

🔗 Read full article on ScienceDirect

#AcuteLungInjury #Necroptosis #NaturalMedicine #CJNM
Discovery based on SPR drug chip that corilagin alleviates acute lung injury in mice by inhibiting necroptosis through targeting RIPK1/RIPK3/MLKL pathway
Necroptosis, a necrotic form of regulated cell death, plays a crucial role in various tissues and disorders, including sepsis. This process occurs pri…
www.sciencedirect.com
January 28, 2026 at 2:04 PM
🫁 Qi-Xian Decoction (QXD) in asthma

A new #CJNM study shows QXD promotes BMSC proliferation and lung migration, reduces airway inflammation, and restores epithelial integrity. 🧬

🔗 Read on ScienceDirect
#Asthma #StemCells #NaturalMedicine #CJNM
Exploring the kidney-tonifying effect of Qi-Xian decoction for asthma treatment by modulating the proliferation and migration of endogenous BMSCs
Traditional Chinese medicine (TCM) establishes that the kidney serves vital systemic functions and its deficiency represents a fundamental factor infl…
www.sciencedirect.com
January 27, 2026 at 1:15 PM
🌿 Epimedium Herba targets prostate cancer through multiple pathways.

A #CJNM study shows it inhibits cancer cell proliferation and induces apoptosis, supported by network pharmacology and in vitro validation.

🔗 www.sciencedirect.com/science/arti...

#CJNM #NaturalProducts #DrugDiscovery
January 26, 2026 at 1:57 PM
🫀 Can Qingda Granule protect kidneys in hypertension?

A #CJNM study shows it preserves mitochondrial function and reduces renal cell apoptosis in hypertensive models.

🔬 Mechanistic insights into mitochondrial protection.

#Hypertension #KidneyDisease #CJNM
Protective mechanisms of Qingda granule in hypertensive kidney injury: Focus on ERK/RSK1-mediated mitochondrial protection
Hypertension represents a significant chronic non-infectious disease in China, where Qingda Granule (QDG) has traditionally been employed for its mana…
www.sciencedirect.com
January 23, 2026 at 3:40 PM
🫁 Can Tracheloside (TCL) slow pulmonary fibrosis?

A #CJNM study shows TCL activates AMPK, suppresses fibroblast differentiation, and reduces oxidative stress—a potential lead for IPF treatment. 🔬
🔗 Read it on ScienceDirect
#PulmonaryFibrosis #AMPK #NaturalProducts #CJNM
AMPK regulates the anti-pulmonary fibrosis effects of tracheloside
Idiopathic pulmonary fibrosis (IPF) presents limited therapeutic options that often involve severe side effects, making the development of innovative …
www.sciencedirect.com
January 22, 2026 at 3:26 PM
🌊 Marine Terpenoids: Nature’s Treasure

New #CJNM review catalogs 13,000+ compounds, revealing unique molecular scaffolds distinct from land plants. 🧬

Insights for next-gen drug discovery! 💊
🔗 sciencedirect.com/science/article/abs/pii/S1875536425000263

#MarineBiology #DrugDiscovery #CJNM
January 21, 2026 at 2:08 PM
🦴 Why is cartilage injury still so hard to treat?

A CJNM review summarizes how bioactive compounds from Traditional Chinese Medicine may regulate inflammation and cartilage repair 🌿🧬

🔗 Full article:
www.sciencedirect.com/science/arti...

#CJNM #CartilageInjury #TCM #RegenerativeMedicine
January 20, 2026 at 2:18 PM
🌿 CJNM is now on Blue Sky!
The Chinese Journal of Natural Medicines (CJNM) brings you the latest research in natural products, TCM, pharmacology, and drug discovery.
Join our community and stay updated on cutting-edge natural medicine research! 🧪💊
#NaturalMedicines #Pharmacology #TCM #DrugDiscovery
January 19, 2026 at 2:40 PM