cmoene.bsky.social
Christine Moene
@cmoene.bsky.social
32 followers 32 following 1 posts
PhD student at the Netherlands Cancer Institute || gene regulation - epigenetics - genome organization || she/her
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mathiaseder.bsky.social
mathiaseder.bsky.social @mathiaseder.bsky.social · 19d
✨Exciting news: the main story of my PhD is out in Science!

Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genome—revealing how Sox2’s position shapes enhancer activation.

📖 Read the full story here: www.science.org/doi/10.1126/...
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene
Genes are often activated by enhancers located at large genomic distances, and the importance of this positioning is poorly understood. By relocating promoter-reporter constructs into thousands of alt...
www.science.org
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cmoene.bsky.social
Christine Moene @cmoene.bsky.social · 19d
Have you ever wondered how the exact location of a gene affects it's activity?

The main story of my PhD deals with exactly that question, and is now published in Science! ✨
www.science.org/doi/10.1126/...

My amazing co-author and friend @mathiaseder.bsky.social summarized the highlights for you
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