Cody Limber
@codylimber.bsky.social
100 followers 140 following 13 posts
Evolutionary Developmental Ornithologist, PhD candidate @Yale EEB interested in feather cell types, cell types evolution, and all things birds https://www.codylimber.com/
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codylimber.bsky.social
One of my favorite parts of writing is remembering that the perfect citation exists and even remembering what one of the figures looks like but not remembering any of the key words that make finding the paper possible
codylimber.bsky.social
This is incredible, congrats!! 🎉
codylimber.bsky.social
Finally, if you’ve got a gene you’re interested in and want to know what cell types it’s expressed in, let me know!! AND if you think this work sounds really cool and interesting, I’ll be looking for postdocs next fall so let’s chat!
codylimber.bsky.social
This work shows how we can connect development, morphology, and evolution. By tracing feather cell development and understanding feather cell type evolution, we can better understand how one of nature's coolest novelties - the feather - evolved!
codylimber.bsky.social
And finally, we made an evolutionary tree of feather cell types. Our tree, which is congruent with the evo-devo model of feather evolution, tells a new story about the homology of feather cells with the layers of the epidermis.
A tree where the tips are different feather cell types
codylimber.bsky.social
Third, we looked at cell-cell signaling pathways and found that cell types only function in development of the feather play important roles in signaling the cells that eventually form the feather.
A circular plot showing signals coming from the marginal plate with their associated receptors in other cell types
codylimber.bsky.social
Second, we mapped developmental trajectories with RNA velocity. We find three trajectories corresponding to the sheath, the barb ridge, and the basal epithelium. This finding implies that the different layers of the skin develop on their own trajectories.
An image of a multicolored UMAP plot with RNA velocity arrows showing developmental trajectories
codylimber.bsky.social
First, we created a cell atlas for developing feathers. We used in situ hybridizations for marker genes and found that we can actually identify feather cell types based on their transcriptome profiles which should be helpful to anyone interested in using single cell sequencing on feathers!
Some example in situ hybridizations on feather cross sections
Reposted by Cody Limber
nhm.org
🪶 Feathers are complex, each one an elegant structure crafted through millions of years of evolution. As habitats shrink and climates continue to warm, understanding the why and how of colorful bird feathers could help us better protect them into the future: go.nhm.org/feathers-work
Archival artist rendering of a variety of birds and their feathers.
codylimber.bsky.social
Presenting tomorrow at #Evol2025, swing by to hear about feathers, cell types, and a little teaser about pigmentation patterns!
codylimber.bsky.social
This is super useful!! Any recommendations for places to go birding?
Reposted by Cody Limber
caseywdunn.bsky.social
I hope to take a PhD student in the coming application cycle. Please reach out if you are interested in joining our lab in EEB at Yale, especially if interested in working on the natural history/ phylogenetics/ morphology/ population biology/ development/ genomics of siphonophores. dunnlab.org
The Dunn Lab
Casey Dunn's laboratory in the Department of Ecology and Evolutionary Biology at Yale University.
dunnlab.org