Lightnews — Scholar-powered news

COLLABORATE Randomised Controlled Trial

@collaborate-rct.bsky.social

32 followers 16 following 17 posts

UK-wide, real-world-data-enabled, adaptive, 2-randomisation, controlled trial to determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing necrotising enterocolitis, mortality, and cognitive impairment in preterm babies

Posts Media Videos Starter Packs

Pinned

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · May 6

Should pasteurised donor milk or preterm formula be used when a supplement for own mother's milk is needed, and is routine protein-carbohydrate fortification of human milk beneficial and safe?

Watch the COLLABORATE explainer video below. youtu.be/hQ3zq08BbRk

COLLABORATE Parent Explainer Animation Video

YouTube video by COLLABORATE Randomised Controlled Trial

youtu.be

Reposted by COLLABORATE Randomised Controlled Trial

Neena Modi @neenamodi1.bsky.social · Jun 6

Honoured to be part of the excellent Middlesbrough neonatal meeting 2025 at James Cook University Hospital! Great science, great friendship, great hospitality! Pleased to discuss the COLLABORATE study www.imperial.ac.uk/neonatal-dat... 🙏🏽🙏🏽🙏🏽 @cardioneo.bsky.social @calumtheroberts.bsky.social

3 2

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · May 6

Subscribe to the COLLABORATE YouTube channel here www.youtube.com/@COLLABORATE...

COLLABORATE Randomised Controlled Trial

An adaptive, 2-randomised, controlled trial to define the role of pasteurised donor milk, preterm formula, and fortifier in extremely preterm care. Coming in 2025.

www.youtube.com

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · May 6

COLLABORATE Parent Explainer Animation Video

YouTube video by COLLABORATE Randomised Controlled Trial

youtu.be

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Apr 25

To download the COLLABORATE Flyers for your use, kindly follow this link : www.imperial.ac.uk/neonatal-dat...

1 1

Reposted by COLLABORATE Randomised Controlled Trial

Neena Modi @neenamodi1.bsky.social · Apr 22

Delighted to link up @neonatalsurgery.bsky.social @fionamet.bsky.social & we’d love to discuss @collaborate-rct.bsky.social with you; a 2-randomisation adaptive RCT to reduce severe NEC & improve cognitive outcomes for extremely preterm babies www.imperial.ac.uk/neonatal-dat...

1 2 3

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Apr 25

#COLLABORATErct is focused on improving newborn care together

Neena Modi @neenamodi1.bsky.social · Apr 13

🙏🏽🙏🏿🙏🏻🙏 to our inspirational delegates from across the 🌍 & many disciplines at Perinatal Science International 2025 all focused on strengthening research to improve care & policies for mothers & babies! @europerinatal.bsky.social @imperialcollegeldn.bsky.social

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Apr 25

The COLLABORATE Trial is funded by NIHR @imperialbrc.bsky.social

Watch the video below for more details:

youtu.be/pOjKbs1neHY

COLLABORATE Explainer Video

YouTube video by COLLABORATE Randomised Controlled Trial

youtu.be

1 1

Reposted by COLLABORATE Randomised Controlled Trial

Neena Modi @neenamodi1.bsky.social · Mar 26

Calling all neonatal teams to help finally resolve longstanding uncertainties re formula, fortifier, pasteurised donor milk & NEC. Join #COLLABORATE_rct @99nicu.bsky.social @europerinatal.bsky.social @nihr.bsky.social

Neena Modi @neenamodi1.bsky.social · Mar 26

SIGNEC2025 London May 22-23 for latest in field & to hear about #COLLABORATE_rct a landmark adaptive, real-world data RCT to resolve uncertainties re NEC, formula, fortifier & pasteurised donor milk @bapmofficial.bsky.social @neonatalnursesuk.bsky.social @ebneo.bsky.social @necsociety.bsky.social

4 5

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Apr 8

Kindly watch the COLLABORATE Explainer video below youtu.be/5uGskrmVqvY

COLLABORATE Explainer Video

YouTube video by COLLABORATE Randomised Controlled Trial

youtu.be

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Apr 8

The COLLABORATE webinar series resume on April 14th.

More information here: lnkd.in/ed_EQhEP

1 2

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Feb 21

Join Session 2 of our webinar series today from 12.00-13.00 with @jamespboardman.bsky.social

Follow this link to join teams.microsoft.com/l/meetup-joi...

Join conversation

teams.microsoft.com

Reposted by COLLABORATE Randomised Controlled Trial

Neena Modi @neenamodi1.bsky.social · Feb 18

Calling all UK neonatal teams! COLLABORATE, an adaptive, 2-randomisation, real-world-data-enabled RCT to reduce NEC will go live 06/25! We are running a series of webinars to explain & discuss the study Join us! All welcome! Web-links at www.imperial.ac.uk/neonatal-dat... @bapmofficial.bsky.social

COLLABORATE | Faculty of Medicine | Imperial College London

www.imperial.ac.uk

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Feb 18

We invite you to join one of our upcoming COLLABORATE webinars where the investigators will explain the study and provide opportunity for discussion. Open to everyone

Session 1: 19th February, 12.00-13.00,

Click through this link to join lnkd.in/ee543ArM

Find more here : lnkd.in/ed_EQhEP

This link will take you to a page that’s not on LinkedIn

lnkd.in

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Feb 18

We are looking for parents of preterm babies who have lived experience of Necrotising Enterocolitis

Kindly email us at [email protected]

Reposted by COLLABORATE Randomised Controlled Trial

Neena Modi @neenamodi1.bsky.social · Jan 26

Is routine fortification of human milk feeds needed for very preterm babies? No RCT has shown neurodevelopmental benefit and 1 has shown harm. That’s why we’re doing @collaborate-rct.bsky.social www.imperial.ac.uk/neonatal-dat...; join us! @bapmofficial.bsky.social @neonatalnursesuk.bsky.social

3 5

Reposted by COLLABORATE Randomised Controlled Trial

James P Boardman @jamespboardman.bsky.social · Dec 17

Randomisation 1 will determine if pasteurised human donor milk or preterm formula affect NEC and other outcomes if a supplement for own mother’s milk is required.

Randomisation 2 will determine if routine macronutrient fortification of human milk is beneficial.

2/2

1 2

Reposted by COLLABORATE Randomised Controlled Trial

James P Boardman @jamespboardman.bsky.social · Dec 17

New RCT coming to the UK in 2025!

COLLABORATE will determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing surgical NEC, mortality, and cognitive impairment in extremely preterm babies.

2 randomisations:

1/2

1 6 5

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Jan 14

Babies deserve generalisable research! Contact us at [email protected]

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Jan 14

We welcome opportunity to support colleagues to deliver the #COLLABORATErct 2-randomisation controlled trial addressing the effects of pasteurised human donor milk, preterm formula, and cow-milk-derived fortifier on necrotising enterocolitis and other outcomes, in their countries.

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Jan 11

COLLABORATE is an efficient, real-world-data-enabled, adaptive, 2-randomisation trial of efficacy, effect size & safety of pasteurised donor milk, cow-milk fortifier & formula in reducing NEC. Summary, explainer video & fliers here: www.imperial.ac.uk/neonatal-dat...

COLLABORATE | Faculty of Medicine | Imperial College London

www.imperial.ac.uk

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Jan 7

COLLABORATE coming this year, will determine effects of donor milk, bovine fortifier & formula on surgical NEC, survival & cognition, key questions for all preterm babies. If interested in being a global partner email [email protected]

2 2

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Dec 17

COLLABORATE Powerpoint Summary of Trial Justification and Design view.officeapps.live.com/op/view.aspx...

view.officeapps.live.com

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Dec 17

Watch this short explainer below: youtu.be/7N1s4kbs0HQ?...

COLLABORATE Explainer Video

YouTube video by COLLABORATE Randomised Controlled Trial

youtu.be

1 1

COLLABORATE Randomised Controlled Trial @collaborate-rct.bsky.social · Dec 17

www.imperial.ac.uk/neonatal-dat...

COLLABORATE | Faculty of Medicine | Imperial College London