Thrilled to introduce Chen Lab to the COMET Leducq project! 🧬Their cutting-edge work on vascular smooth muscle cells, multi-Omics, AI, and translational models is driving new insights into vascular disease, aging, and drug discovery. Excited for the collaboration ahead!

🔬 Kramann’s Lab bridges kidney, heart & fibrosis research to turn single-cell and spatial genomics into new therapies. From mapping fibrotic cell states to 3D bioprinted kidneys and iPSC organoids, they’re redefining how we model and treat disease.
#COMETLeducq #KramannLab #Fibrosis #CardioRenal

Thrilled to share that Meng-Ying Wu has received the 2026 COMET Leducq Early Investigator Award! 🎉 Her project will uncover the epigenetic regulators driving vascular calcification and VSMC fate switching - paving the way for new cardiovascular therapies. 🔬✨

Dr. Kuldeep Singh, Instructor at MGH & Harvard Med, is a 2026 COMET Leducq Early Investigator Award recipient! 🎉
His research integrates multi-omics & single-cell RNA-seq to uncover genetic drivers of vascular calcification & atherosclerosis, advancing cardiovascular disease understanding.

Introducing Dr. Chengyun Tang – 2026 COMET Leducq Early Investigator Award Recipient ✨

Her research applies AI, single-cell, and spatial transcriptomics to reveal how vascular calcification drives brain aging and late-life dementia. Thrilled to see where her work leads!
#cometleducqnetwork

Thrilled to announce Patrick Hart (University of Virginia) as one of the 2026 COMET Leducq Early Investigator Award recipients! 🎉

Patrick’s research explores how diabetes contributes to atherosclerosis using advanced multi-omic and epigenetic approaches.

#COMETLeducqNetwork #CardiovascularScience

🔬 Introducing the Duer Research Group (Cambridge Chemistry) - exploring tissue molecular structure and the extracellular matrix to understand ageing, disease, and vascular calcification.
Their discoveries led to a new therapy now in trials. Proud members of COMET Leducq ☄️#COMETLeducq

Hosting the 2nd COMET Leducq Network Meeting in beautiful Boston! 🌟 A fantastic week of inspiring science, collaborations, and discussion as our PIs and Fellows share their research journeys - all alongside great company and delicious food. 💙 #COMETNetwork #LeducqFoundation

Cathy and Meng are at the Joint Europe Calcification Meeting 2025, and Meng won 1st place for her oral presentation! 🏆

A day of insightful talks, engaging discussions, and inspiring posters highlights the passion of this vibrant research community.

Meet the Miller Lab, Univ. of Virginia! @clintomics.bsky.social

They study genetic & environmental risk factors for coronary artery & complex cardiovascular diseases using multi-omics, genomic datasets & functional models, aiming to uncover disease mechanisms & new strategies for prevention.

Cathy Shanahan, one of our PIs, recently attended the ESC Congress in Madrid, Europe’s premier cardiovascular meeting. She chaired a session on cardiac macrophages and was a poster discussant on immunometabolism, inflammation, and vascular disease.
#COMETLeducqNetwork #Reserach

Meet Professor Cathy Shanahan’s Research Team
📍 King’s College London

Cracking the code of vascular aging - Shanahan Lab is uncovering how smooth muscle cells drive calcification & stiffness, paving the way for new heart disease therapies.

#MeetTheTeam #CardioScience #COMETLeducq

👏Big congrats to Dr. Sujin Lee for winning the Outstanding Research Fellow Mentor Award AND the SVS Foundation Award for her research on the FNDC1 protein in vascular calcification! She’s been a Malhotra Lab fellow since 2021, supported by an NIH F32 grant. Amazing work!
#VascularResearch #STEM #MGH

Meet Dr. Rajeev Malhotra’s 2025 Research Team @rajmalhotramd.bsky.social 💫
From the Cardiovascular Research Center (CVRC), MassGeneral Brigham, Boston—Dr. Raj’s lab explores vascular calcification & atherosclerosis, uncovering targets for future therapies.
#MeetTheTeam#MGH#CardioResearch#cometleducq

Throwback to our first official COMET Leducq conference in London this May! After insightful sessions, we capped it off with a ride on the London Eye and a scenic river cruise—networking, laughter, and unforgettable views. #COMETLeducq #London #Networking

Dr. Chen chaired a scientific session and her team presented exciting new findings on vascular calcification at #Pathobiology2025 by @asipath.bsky.social. A proud moment for the lab pushing boundaries in cardiovascular research!

#COMET2025 #COMETLeducq #CardioScience #CardioResearch

Breaking boundaries in heart science!

The first COMET Network meeting brought global experts to London to decode vascular calcification using cutting-edge omics.

Collaboration, discovery, and a path toward targeted therapies.

#COMET2025 #COMETLeducq #CardioScience

Introducing COMET (Calcification-Omics, Molecular Elucidation & Therapeutics)!

We’re decoding vascular calcification using cutting-edge genomics and molecular science to tackle heart disease and reduce cardiovascular risks.

Join us on this exciting journey!
#COMETLeducq #CardioScience

We’re live on Bluesky!

Excited to share our first update: At the American Heart Association in 2024, Dr. Chen led a session on Vascular & Valvular Calcification, where @rajmalhotramd.bsky.social presented a talk on Clinical Genomics in Cardiovascular Calcification.

#COMETLeducq #CardioScience