Coscia Lab
@coscialab.bsky.social
210 followers 74 following 9 posts
...we are passionate about spatial proteomics, mass spectrometry and single-cell technologies to study disease mechanisms @MDC_Berlin 🇩🇪🇨🇴🇨🇳🇰🇿🇵🇷🇵🇱🇲🇽
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coscialab.bsky.social
Check out our latest preprint in collaboration with the @garyrlewin.bsky.social lab! We obtained the first subset-specific proteomes of pain sensing neurons!
amapruns.bsky.social
We present the first subset-specific proteomic signature of electrophysiologically-defined, pain-sensing neurons. One step closer to uniting function with molecules- one neuron at a time. Thanks to all who have contributed, especially @coscialab.bsky.social @garyrlewin.bsky.social #neuroscience
biorxivpreprint.bsky.social
Ultrasensitive proteomics uncovers nociceptor diversity and novel pain targets https://www.biorxiv.org/content/10.1101/2025.09.20.677124v1
coscialab.bsky.social
Excited to introduce openDVP — an open-source framework to bring deep visual proteomics to the broader research community! It includes:
– A simplified fast-track pipeline for easy adoption
– An AI-powered option for advanced image & spatial analysis
👉 BioRxiv: bit.ly/44SBuHu
👉 Github: bit.ly/4eR3IqK
coscialab.bsky.social
Great work Luke! Any new protocols in our field are helpful to get people started with SP. As you point out, lab specific infrastructure is a very relevant aspect as well. And thanks for the flowers 😅
coscialab.bsky.social
Our lab's newest preprint is out on deep spatial proteomics of ovarian cancer precursor lesions!
We demonstrate how ultrasensitive discovery proteomics can shed light onto early carcinogenesis, uncover cell-of-origin signatures, and prioritize novel drug targets.
bit.ly/41M7fke
Deep spatial proteomics of ovarian cancer precursor lesions delineates early disease changes and cell-of-origin signatures
High-grade serous ovarian cancer (HGSOC) is a devastating disease that is frequently detected at an advanced and incurable stage. Advances in ultrasensitive mass spectrometry-based spatial proteomics ...
www.biorxiv.org
Reposted by Coscia Lab
Reposted by Coscia Lab
ukbspr.bsky.social
Our selected speakers doe rhe different sessions are:
Georg Kustacher - bioinformatics
@coscialab.bsky.social single cell/spatial session
Manuel Mayr - clinical proteomics
Richard Seltema - structural
Freddie Theodolou - non-human proteomics
Jyoti Choudary - functional proteomics
Reposted by Coscia Lab
itaiyanai.bsky.social
"Innovations in Single Cell Omics" Berlin 5.12-13.
Keynote Speakers:
@shalinhnaik.bsky.social
Pulin Li, and me!
Invited Speakers:
@emmanuel-saliba.bsky.social
@mratz.bsky.social
Barbara Grünwald
Maria Colomé-Tatché
Mohammad Lotfollahi
@coscialab.bsky.social
Teresa Krieger
www.isco-conference.eu
ISCO - ISCO
www.isco-conference.eu
coscialab.bsky.social
Wonderful group dinner tonight, #proudPImoment ☺️🫶
coscialab.bsky.social
Next up at the @fogenomics.bsky.social proteomics stage, @ajbrenes.com talking about single-cell proteomics applied to neutrophils. Cool stuff!
coscialab.bsky.social
Thanks Alastair! :-)
coscialab.bsky.social
Extremely happy that our Deep Visual Proteomics pipeline is one of the highlighted @naturemethods.bsky.social Spatial Proteomics approaches! 🥳 Congrats to the growing DVP team(s)! Making it broadly accessible & advancing it to the multiomics space is a key mission in our lab @mdc-berlin.bsky.social