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David Garfield @dagarfield.bsky.social · Aug 14

LOVE IT

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David Garfield @dagarfield.bsky.social · Aug 14

I am on a one man mission to slide marine invert citations into my pharma work. It is....slow going.

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David Garfield @dagarfield.bsky.social · Aug 14

I want to scream at those people: MOST LIFE ON THIS PLANET LOOKS MORE LIKE A MARINE CREATURE THAN A HUMAN IN TERMS OF GENETIC VARIATION

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David Garfield @dagarfield.bsky.social · Aug 13

Congrats to Jonas on the pre-print of his primary thesis work!
www.biorxiv.org/content/10.1...

The Establishment of Cell-Type Specific Gene Regulation in the Sea Urchin Embryo

Cell-fate commitment in metazoan development relies on precise gene regulatory programs. This study presents a comprehensive single-cell atlas of gene expression (scRNA-seq), nascent transcription (sc...

www.biorxiv.org

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David Garfield @dagarfield.bsky.social · Feb 12

No, because it was never about efficiency....

David Garfield @dagarfield.bsky.social · Feb 12

I am not curious. The answer is no. But it isn't hypocrisy. Its only hypocrisy if you think these cuts were about efficiency in the first place.

David Garfield @dagarfield.bsky.social · Feb 12

I think he understands perfectly well but chooses to say that stuff anyways.

David Garfield @dagarfield.bsky.social · Feb 12

I don't know about you, but I enjoyed President Musk's first oval office press conference. He even brought his kid and some sort of orange puppet to entertain him. He's a nice dad.

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David Garfield @dagarfield.bsky.social · Feb 12

No. That is very fair.

David Garfield @dagarfield.bsky.social · Feb 11

Eh....its not like there aren't problems over there.

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David Garfield @dagarfield.bsky.social · Feb 8

There might be something to this if the administration returned this money to researchers. Is that going to happen...doubt it.

In any case, this is a stupid way to do reform. In fact, its literally the opposite because now we get chaos and lawsuits.

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Reposted by David Garfield

Carl T. Bergstrom @carlbergstrom.com · Feb 8

1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...

NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

grants.nih.gov

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David Garfield @dagarfield.bsky.social · Feb 4

And growing! But its OK. I'll have yours.

David Garfield @dagarfield.bsky.social · Feb 4

WHY ARE THEY NOT FILING A BILLION LAWSUITS???

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David Garfield @dagarfield.bsky.social · Feb 2

My child really eats only avocados and berries. This is going to suck....

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David Garfield @dagarfield.bsky.social · Jan 31

Why are so many of my human functional variants outside of TFBS?? (or ones I know about)

David Garfield @dagarfield.bsky.social · Jan 31

Thanks but also no thanks? Now I have one more thing to check.... ;)

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David Garfield @dagarfield.bsky.social · Jan 31

More TFBS with larger genome? Or the other way?

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David Garfield @dagarfield.bsky.social · Jan 31

I had not heard that story before. I'm bothered by how often this sort of money shifting happens. This was also essentially what happened to my group leader position -- the University shifted funds around and then the budget got tight and suddenly...surprise! No more money for juniors.

David Garfield @dagarfield.bsky.social · Jan 31

How general do you think this is in life (or at least plant life) vs. (maybe??) some kind of impact for how variation is selected as part of the breeding process? Its really striking how localized your results are for TFBS and not "regulation" in a more general sense.

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David Garfield @dagarfield.bsky.social · Jan 31

Oh, thanks for this. I actually needed a citation for more or less this point. Perfect.

David Garfield @dagarfield.bsky.social · Jan 31

Does it involve a gentle fight over shadow enhancers? I'm stuck in a wormhole of papers since last week....thanks for that..... ;)

David Garfield @dagarfield.bsky.social · Jan 31

Please consider taking Anshul up on his offer. Many of us are waiting for the results of this cool project ;)

Anshul Kundaje @anshulkundaje.bsky.social · Jan 31

Would be happy to be a faculty mentor for PD candidates with interests in our labs work. We're building a foundation of 10,000s of highly interpretable, robust, efficient deep learning models of multiple layers of gene regulation across fetal and adult cell states. 1/

Sam Rodriques @sgrodriques.bsky.social · Jan 31

Applications for the FutureHouse Independent Postdoctoral Fellowship are due in two weeks! $125k annual stipend, full access to our resources, be coadvised by world class professors and apply our AI science agents to make new discoveries. Apply!

Details here: www.futurehouse.org/fellowship

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David Garfield @dagarfield.bsky.social · Jan 31

Did you think you were too late for a cool summer internship? Think again! 12 weeks of awesomeness on aging and partial reprogramming working with some great post-docs from the Jasper and Marioni labs at Genentech.

roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...

2025 Summer Intern - Regenerative Medicine

2025 Summer Intern - Regenerative Medicine Department Summary As part of Genentech Research & Early Development (gRED), the department of Regenerative Medicine is at the forefront of developing no...

roche.wd3.myworkdayjobs.com

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David Garfield @dagarfield.bsky.social · Jan 31

But don't you think all the problems will be solved by GrokAI? Clearly.