Dan Kaplan
@danhkaplan.bsky.social
690 followers 350 following 12 posts
Immunologist and Dermatologist at the University of Pittsburgh. The lab is interested in the interactions between immune and non-immune cells, especially sensory neurons.
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danhkaplan.bsky.social
Derm on Drugs is a podcast where some current and former U of Pitt faculty talk about dermatology. Here is an episode where I joined to talk about itch and scratching. It was a really fun time and they did a great job. #dermatology #immunology #eczema podcasts.apple.com/us/podcast/d...
To Scratch or Not to Scratch, That Is the Question
Podcast Episode · Derms on Drugs · 03/14/2025 · 36m
podcasts.apple.com
danhkaplan.bsky.social
I was scheduled for study section starting tomorrow. Everything's all done and ready to go. Just heard it's being "rescheduled." No reason given.
danhkaplan.bsky.social
But winter itch is all about dryness. Moisturize!!!
danhkaplan.bsky.social
It does suggest that targeting mast cells is something to focus on.
danhkaplan.bsky.social
My PO says ours at end of Feb is still on. But who knows.
danhkaplan.bsky.social
Also big thanks to the labs of Marlies Meisel and Tina Sumpter here at Pitt and all co-authors.
danhkaplan.bsky.social
And I found some choice photographs to show for the introduction!!!
danhkaplan.bsky.social
New paper from Kaplan Lab. Agonizing a specific glutamate receptor on mast cells in the skin renders them less function and can suppress several models of skin inflammation. Congrats to Youran Zhang and all co-authors. #skinimmunology #immunology #mastcells www.science.org/doi/10.1126/...
Agonism of the glutamate receptor GluK2 suppresses dermal mast cell activation and cutaneous inflammation
Small-molecule agonism of GluK2 reduces dermal mast cell responses to MrgprB2 ligation and suppresses skin inflammation.
www.science.org