𝐂𝐨𝐦𝐩𝐚𝐧𝐲 𝐓𝐨𝐮𝐫: BiotechTV visited the new offices of @seaporttx.bsky.social today and was given a tour by Founder & CEO @daphnezohar.bsky.social

For @biotechtv.bsky.social's Biotech CEO Sisterhood series, our CEO @daphnezohar.bsky.social spoke to Sophie Kornowski on her journey leading Boston Pharmaceuticals to a $2B deal w/ GSK. Check this out for insights from both leaders on dealmaking, leadership strategies & mentorship: bit.ly/4m55kzG

Pleased to announce the first patient has been dosed in our Ph2b BUOY-1 study of GlyphAllo™ (SPT-300) in #MDD w/ or w/o anxious distress, an important milestone for Seaport’s pipeline that brings us closer to a potential new treatment for patients w/ MDD: bit.ly/3Uhn3YB

#BiotechHangout Eric Schmidt, Brad Loncar, Tim Opler, Tess Cameron on M&A: $MRK/$VRNA, $ABBV/Capstan, biotech takeouts, M&A wave, pharma’s $150B in LOE, plus Trump’s BBB/tariffs, $XBI & MFN, FDA’s CRL disclosures, $CAPR, $KALV, $PROK, obesity trends, $RARE/$MREO, $ABBV/Ichnos: bit.ly/3TuICVp

The Seaport crew kicked off summer with a fun gathering! Great opportunity to connect out of the office, strengthening our mission to develop life-changing medicines for #neuropsychiatric disorders. Looking forward to more moments together and progress towards transforming lives!

As #MentalHealthMonth closes, we welcomed a @namicommunicate.bsky.social patient representative to share his journey w/ mental health conditions. His story inspires our work at Seaport to help those struggling & develop new medicines for #depression & #anxiety. More: www.nami.org

#BiotechHangout: Chris Garabedian, Josh Schimmer, Nina Kjellson, Mike Yee, Tim Opler on market sentiment – where is the M&A?, FDA/CBER, wind downs vs reverse mergers, policy: #MAHA & COVID vaccine, $REGN/23andMe, data: $RCKT, psychedelics, $PRTA, $SPRO/$GSK, $GILD, $SMMT, #ASCO & more bit.ly/4dCFzDT

Two people were shot and killed outside a Jewish LGBTQ event in D.C.

This #MentalHealthMonth, we joined @namicommunicate.bsky.social's annual #NAMIWalks to combat stigma & promote mental health awareness. We stand with those affected by mental illness & are dedicated to developing new medicines for #depression & #anxiety. More about NAMI www.nami.org

#BiotechHangout: Sam Fazeli, John Maraganore, Nina Kjellson, Matt Gline on MFN: 30-day ultimatum, 180 days negotiation, reimportation, ex-US prices, DTC, Roche, $SNY, plus: budget reconciliation, IRA, $RXRX, Galapagos, $CTMX, $GSK buys Boston, $GSK/iTeos, $NVO CEO, RNA deals: bit.ly/3S3vhTh

Linked in and X

Seems like Bluesky is losing momentum? Wouldn’t mind having one less place to check/post. Curious to hear from others

Important provisions added to reconciliation bills would be positive for bio if passed:

ORPHAN Cures Act included, amend IRA

PBM reforms delinking compensation from list price, increasing transparency & banning spread pricing in Medicaid

Tax fix to allow for immediate deduction of R&D costs

Cantor has put out some really interesting notes lately. Dueling takes from Eric Schmidt & Josh Schimmer on short selling last week and then this week a thoughtful critique of issues that are ailing our industry. Link below:
cantor2.bluematrix.com/sellside/Ema...

#BiotechHangout: Eric Schmidt, Sam Fazeli, Adam Feuerstein, Peter Kolchinsky on $XBI, market & macro trends, latest from FDA/Washington, Q1 earnings trends: tariffs, M&A & drug launches, data: $SMMT/Akeso & #AUA2025 & #AACR25 recap ($PFE, $JNJ, $BNTX, $CGON, China ADCs): twitter.com/i/spaces/1gq...

#Depression & #anxiety are among the most common & disabling #mentalhealth conditions. This #MentalHealthAwarenessMonth we're spotlighting our commitment to developing better medicines & reducing the stigma for those dealing w/these conditions. Learn more: www.seaporttx.com

“When Secretary Kennedy offers a suggestion to me, he always adds, “You decide for yourself.” So, yes, there is independence.” New interview with Marty Makary sheds more light on re-org (no plans), PDUFA dates, morale and his independence from RFK insidemedicine.substack.com/p/exclusive-...

#BiotechHangout: Daphne Zohar, Josh Schimmer, Tim Opler, John Maraganore, Paul Matteis on macroenvironment, $XBI, $SWTX $MRCG takeout rumors, policy: (FDA, tariffs), data: ($BMY, $QURE, #AUA25: $JNJ/$CGON), Trump vs. Harvard, buyside & short-selling, CEO survival tips: x.com/biotechch/st...

We're at #SOBP2025 to present new preclinical data on SPT-320, a novel oral prodrug of agomelatine. SPT-320 increased lymphatic transport >50% compared to <1% agomelatine alone & increased plasma exposure >10-fold. SPT-320 progressing into clinic for #GAD. bit.ly/4ixtOzs

Makary interview: “Why does it take 10 years to bring a drug to market in US? People are dying. Our # 1 goal is delivering cures, meaningful treatments, healthier food” 1 randomized controlled trial & then intense post marketing surveillance (link for full text):
www.linkedin.com/posts/daphne...

Insider close to administration: Elon’s DOGE work almost done. Lutnick & Navarro losing influence & Bessent gaining. Most interesting: “If Secretary of HHS makes it through the year I’ll be shocked.” Oz important. Last night’s EO opportunity “pill penalty.” Sounds like they’re coming after CVS/PBMs

Thank you 🙏

Congrats @daphnezohar.bsky.social, named to @statnews.com #STATUSList, "the ultimate list of leaders in health, medicine, & science," for founding Seaport & raising $325M. “That’s big & her influence on the biotech field extends beyond that” & cofounding Karuna & PureTech bit.ly/4coOF6B