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Duke Clinical Research Institute @dcrinews.bsky.social · 14h

📢 New Episode Alert: “It’s Not Just the Scale: Supporting Sustainable Change in Obesity Treatment”

In Part 1 of our obesity series, Emily O’Brien and Manesh Patel dive into what sustainable weight change really looks like with Jennifer Norris, PA-C.

dcri.org/blog/s2-ep-3...

S.2 Ep. 3 | It's Not Just the Scale: Supporting Sustainable Change in Obesity Treatment

In the first episode of a three-part series on obesity and GLP-1 medications, hosts Manesh Patel and Emily O'Brien sit down with Jennifer Norris, a physician assistant at the Duke Center for Metabolic...

dcri.org

Duke Clinical Research Institute @dcrinews.bsky.social · 2d

A recent analysis of the CARE-HK registry indicates that a reduced risk for death may balance out concerns about hyperkalemia when treating heart failure with RAS inhibitors MRAs. Learn more about the findings, featuring insights from DCRI’s Stephen Greene: www.medscape.com/viewarticle/...

Lower Mortality May Offset Hyperkalemia Risk of HF Therapies

New evidence suggests decreased mortality could outweigh an elevated risk for hyperkalemia in patients heart failure treated with RAS inhibitors or mineralocorticoid receptor agonists.

www.medscape.com

Duke Clinical Research Institute @dcrinews.bsky.social · 6d

Millions of Americans with heart failure struggle to get the medications they need. Yet a new Duke Health led by DCRI Faculty member Adam DeVore showed that a remote care program provided patients with a safe and accessible way to get the care required: corporate.dukehealth.org/news/remote-...

Remote Health Care Helps Heart Failure Patients Get the Right Medications Faster

DURHAM, N.C. – For millions of Americans living with heart failure, getting the right medications at the right doses can be a slow and frustrating process, which can lead to delayed treatment adjustme...

corporate.dukehealth.org

Duke Clinical Research Institute @dcrinews.bsky.social · 7d

Have you listened to the latest Beyond the Headlines episode of our Beyond the Endpoint podcast? Tune in on your preferred streaming platform, and let us know what topics you'd like to see hosts Emily O'Brien and Manesh Patel cover in a future episode! dcri.org/blog/s2-ep-2...

S.2 Ep. 2 | Beyond the Headlines

The "Beyond the Headlines" series returns with a look at the summer headlines impacting healthcare and research. Hosts Manesh Patel and Emily O'Brien begin by discussing funding for medical research, ...

dcri.org

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Duke Clinical Research Institute @dcrinews.bsky.social · 9d

At #ESC2025, AQUATIC trial results showed aspirin is harmful for those with OAC 6+ months removed from PCI. Discussant & DCRI Faculty member Renato Lopes said these results show the importance of randomized trials to find “the antithrombotic sweet spot”: www.tctmd.com/news/aquatic...

AQUATIC: More Than 6 Months After PCI, Don’t Use Aspirin With OAC

The “antithrombotic sweet spot” means continuing with oral anticoagulation alone in the chronic phase, Renato Lopes says.

www.tctmd.com

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Duke Clinical Research Institute @dcrinews.bsky.social · 13d

Cognitive functional therapy, an individualized approach to managing chronic pain, has shown promising results as a way to treat back pain. DCRI Faculty member Steven George and other experts share their thoughts on the treatment: www.washingtonpost.com/wellness/202...

This therapy for chronic back pain can be surprisingly effective

A personalized approach that uses physical and psychological coaching may help some people manage their chronic, disabling pain.

www.washingtonpost.com

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Duke Clinical Research Institute @dcrinews.bsky.social · 14d

🚨 New Episode Alert:

Season 2’s Beyond the Headlines Series kicks off with Emily O’Brien and Manesh Patel unpacking what’s making waves in medical news:

• Funding research
• Vaccines
• Sleep Health
• AI in Healthcare

🎧 Tune in for the full conversation!

dcri.org/blog/ep-2-be...

Ep. 2 | Beyond the Headlines

The "Beyond the Headlines" series returns with a look at the summer headlines impacting healthcare and research. Hosts Manesh Patel and Emily O'Brien begin by discussing funding for medical research, ...

dcri.org

2

Duke Clinical Research Institute @dcrinews.bsky.social · 16d

New research featuring DCRI’s Stephen Greene assessed the effects of GLP-1RAs on heart failure hospitalization and cardiovascular death across populations with varying type and number of CKM comorbidity, finding the treatment helped reduce deaths. Read more: onlinelibrary.wiley.com/doi/10.1002/...

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Duke Clinical Research Institute @dcrinews.bsky.social · 19d

At #ESC2025, PARACHUTE-HF lead investigator & DCRI Faculty member Renato Lopes shared how the study results are "a first step in the right direction" for those heart failure caused by Chagas disease. Read more about the results: www.tctmd.com/news/parachu...

#CardioSky #clinicalresearch

PARACHUTE-HF: Sacubitril/Valsartan Effective in Neglected Chagas Cardiomyopathy

The benefit was driven by changes in NT-proBNP, but experts hope the trial sets the stage for more studies of Chagas disease.

www.tctmd.com

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Duke Clinical Research Institute @dcrinews.bsky.social · 20d

In a recent editorial for JAMA, DCRI’s Gerald Bloomfield shares his perspective on the WHO STEPS program, emphasizing how new STEPS surveys must not only track risk, but also help countries define and deliver cardiovascular health: jamanetwork.com/journals/jam...

WHO STEPS and the Future of Cardiovascular Disease Prevention

By the early 2000s, noncommunicable diseases (NCDs) had become the dominant global health threat, yet most countries lacked even the most basic data to guide prevention. In response, the World Health ...

jamanetwork.com

Duke Clinical Research Institute @dcrinews.bsky.social · 23d

We’re excited to announce that Matt Healy will be joining the DCRI! Matt will serve as a member of the DCRI Executive Team, and will assume the role of Chief Operating Officer on November 1.
Join us in extending a warm welcome to Matt!

Duke Clinical Research Institute @dcrinews.bsky.social · 27d

DCRI Faculty member Jennifer Rymer served as the lead author on a new study of nearly 170,000 patients that showed no significant increase in heart attacks during the weeks surrounding daylight saving time. Read more: medschool.duke.edu/news/dayligh...

#CardioSky

Daylight Saving Time May Not Trigger Heart Attacks After All, Study Finds

Duke University School of Medicine study of 170,000 patients found no spike in heart events around daylight saving time, but sleep loss still poses risks for long-term health.

medschool.duke.edu

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Duke Clinical Research Institute @dcrinews.bsky.social · 28d

🚨 BTE Season 2 is here!

Dr. Lauren Franz joins hosts Emily O'Brien and Manesh Patel to explore how research informs care and helps families with navigating autism.

dcri.org/blog/s2-ep-1...

#autism #beyondtheendpoint #clinicaltrials

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Duke Clinical Research Institute @dcrinews.bsky.social · 29d

Season 2 of Beyond the Endpoint kicks off tomorrow!

Tune in to our season premiere episode Understanding Autism: Insights from Research and Practice, which dives into autism research, care, and community.

#podcast #autism #clinicalresearch

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Duke Clinical Research Institute @dcrinews.bsky.social · Sep 8

DCRI’s Manesh Patel recently joined HCPLive to discuss the new AHA & ACC hypertension guidelines, explaining key takeaways like the increased emphasis on lifestyle changes, GLP-1 receptor agonists, and exciting future treatments and trials: www.hcplive.com/view/updatin...

#CardioSky

Updating the Hypertension Treatment Landscape With Manesh Patel, MD

Patel addresses the updated AHA/ACC hypertension guidelines, explaining important features and highlighting the potential of newer therapies.

www.hcplive.com

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Duke Clinical Research Institute @dcrinews.bsky.social · Sep 4

At the recent #ESCCongress, DCRI faculty shared late-breaking study results & participated in discussions on cardiovascular challenges. Get the rundown on the two late-breaking “Hot Line” presentations from Neha Pagidipati and Renato Lopes here: dcri.org/news/dcri-fa...

DCRI faculty share late-breaking study results, lead key discussions on heart health at European Society of Cardiology Congress

Faculty members and fellows of the Duke Clinical Research Institute (DCRI) shared their expertise during the European Society of Cardiology Congress (ESC) in Madrid, Spain, Aug. 29—Sept. 1.

dcri.org

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Duke Clinical Research Institute @dcrinews.bsky.social · Sep 3

The latest DCRI Accomplishments story highlights recent achievements from faculty members Manesh Patel, Julius Wilder, Gerald Bloomfield, and Scott Palmer, as well as this year's Excellence Award winners. Read more: dcri.org/news/dcri-ac...

DCRI Accomplishments – Summer 2025

DCRI Accomplishments showcases the publications, awards, and other achievements of our faculty members. Each quarter, a new collection will highlight the most recent accomplishments.

dcri.org

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Duke Clinical Research Institute @dcrinews.bsky.social · Aug 29

It's the first day of #ESCCongress! We'll be posting rundowns of DCRI sessions each day of the conference. Today, DCRI's Nishant Shah will be sharing his presentation on comorbidities and prognosis in chronic coronary syndromes.

#clinicaltrials #clinicalresearch #cvd

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Duke Clinical Research Institute @dcrinews.bsky.social · Aug 28

Season 2 of the DCRI's Beyond the Endpoint podcast is right around the corner! Get a sneak preview of what topics you can expect to see covered below, and catch up on any episodes from season 1 you might have missed here: dcri.org/bte-podcast/...

Duke Clinical Research Institute @dcrinews.bsky.social · Aug 25

DCRI Fellow Ben Catanese shared his thoughts on a recent study that explored the association of eGFR slope with progression of pre-clinic heart failure (HF) to clinical HF. Read the full article on ‪@ajkd.bsky.social: ajkdblog.org/2025/08/20/o...

#clinicaltrials #MedSky

One Metric, Two Missions: How eGFR Slope Guides Risk and Research

Dr. Benjamin Catanese is a current clinical research fellow in the Duke Division of Nephrology and a research fellow at the Duke Clinical Research Institute pursuing a Master of Health Sciences in …

ajkdblog.org

Duke Clinical Research Institute @dcrinews.bsky.social · Aug 21

DCRI’s Nishant Shah was one of the experts who participated in a new article covering the American Heart Association National Integrated ASCVD Initiative, which increased lipid management referrals and LDL-C monitoring across 6 sites. Read more: www.ahajournals.org/doi/full/10....

#CardioSky

American Heart Association National Integrated ASCVD Initiative: An Implementation Initiative to Improve Lipid Management Among Patients With ASCVD | Circulation: Cardiovascular Quality and Outcomes

www.ahajournals.org

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Duke Clinical Research Institute @dcrinews.bsky.social · Aug 20

Did you know the mitochondria may play a key role in treatment for diseases such as Alzheimer’s and Parkinson’s? DCRI’s Laurie Sanders shares insights into the research her and her team did on mitochondrial dysfunction and Parkinson’s: www.nih.gov/news-events/...

#clinicaltrials #clinicalresearch

Mitochondria and health

Your cells’ mitochondria produce almost all the energy your body needs to survive. They also play a role in many other vital cellular functions. This feature looks at how insights about these cellular...

www.nih.gov

Duke Clinical Research Institute @dcrinews.bsky.social · Aug 14

New results show a simplified two-dose antibiotic treatment may be just as effective as long-term IV therapy for serious staph bloodstream infections. For DCRI Faculty member Thomas Holland, this represents a “a meaningful shift” in treatment:
corporate.dukehealth.org/news/two-dos...

Two-Dose Antibiotic Offers New Hope for Treating Deadly Staph Infections

DURHAM, N.C. – A new study shows that a simplified two-dose antibiotic treatment may be just as effective as traditional long-term IV therapy for serious staph (staphylococcus) bloodstream infections,...

corporate.dukehealth.org

Duke Clinical Research Institute @dcrinews.bsky.social · Aug 13

While current GDMT scores capture omissions and underdosing, they may miss speed and delays. DCRI’s Stephen Greene and Satoshi Shoji reflect on this need to track initiation and capture any delays in a new editorial for the American Heart Association: www.ahajournals.org/doi/10.1161/...

#CardioSky

Simultaneous or Rapid Sequence Optimization of Medical Therapy for Heart Failure: Time to Keep Score | Circulation: Heart Failure

www.ahajournals.org

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Duke Clinical Research Institute @dcrinews.bsky.social · Aug 11

Donna Parker, Director of DCRI’s i-Cubed, recently joined Alloy Partners for an insightful conversation on how innovation, entrepreneurship, and cross-industry partnerships are shaping clinical trials. Listen to the full episode here: www.alloypartners.com/articles/adv...

#clinicaltrials #podcast

Advantaged Podcast, S2E04: The Future of Clinical Trials (with Duke Clinical Research Institute) | Alloy Partners

A conversation with Donna Parker (DCRI/i-Cubed) on clinical trial innovation, industry partnership, and startup engagement in transforming healthcare.

www.alloypartners.com