Drug Discovery Unit, University of Dundee
@ddu-dundee.bsky.social
340 followers 520 following 37 posts
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Reposted by Drug Discovery Unit, University of Dundee
mdr-ddu.bsky.social
#Chagas disease remains very neglected, and not only in the US, in spite of an estimated 8 million people being infected with T. cruzi. We, and our collaborators, aim to develop new medicines, but this is becoming increasingly challenging due to lack of funding.

www.theguardian.com/us-news/2025...
‘Kissing bug’ disease should be treated as endemic in US, scientists say
People in at least eight states have been infected with Chagas, new report says, amid low awareness of disease
www.theguardian.com
Reposted by Drug Discovery Unit, University of Dundee
unleash-as.bsky.social
Good morning Bluesky!
We have reached the end of our UNLEASH meeting and are all preparing to head home.
We are full of enthusiasm and renewed purpose, and we look forward to keeping you all updated on our work!

Tell us - what do you want to know about us?

#SciComm #RNA #Splicing
ddu-dundee.bsky.social
Good morning Sky-Friends!
Our own @biochemtrix.bsky.social (and occasional poster!) is in Germany at the #Unleash consortium meeting. They are joining us here in the sky @unleash-as.bsky.social so follow along to find out about #AlternativeSplicing!
Reposted by Drug Discovery Unit, University of Dundee
mdr-ddu.bsky.social
Great opportunity to join our multi-partner collaboration to develop much needed new #antifungal drugs!

#jobs, #drugdiscovery, #Cryptococcus, #Candida

@mrccmm.bsky.social @ddu-dundee.bsky.social @labwyllie.bsky.social @glaxosmithkline.bsky.social
mrccmm.bsky.social
🚨 Join the MRC CMM 🚨

Assay Development Scientist 1:
buff.ly/0RfOxPP

Assay Development Scientist 2:
buff.ly/qEgHd7Z

Postdoc Research Associate Drug Discovery:
buff.ly/8u2TV1S

Technician Assay Development & Drug Discovery:
buff.ly/CITpQ69
Reposted by Drug Discovery Unit, University of Dundee
wisarchive.bsky.social
Nuclear physics pioneer Harriet Brooks was born OTD 149 years ago. The discoverer of Nuclear Recoil, the transmutation of elements through radioactivity, and nuclear series, her productive career was brought short by marriage. Here is her story

tinyurl.com/mvcd3ape

#WomenInSTEM #Physics #HistSci 🧪
Wither: The Many Triumphs and Long Fall of Nuclear Physicist Harriet Brooks.
Reading the life of Harriet Brooks is like watching the gradual, inevitable unfolding of a horror movie. There's that same idyllic, promising beginning that suddenly gives way as the heroine puts her...
tinyurl.com
Reposted by Drug Discovery Unit, University of Dundee
pwk2024.bsky.social
Opportunity for computational chemist at Syngenta (Stein Switzerland) #CompChem #cheminformatics #ML #AI #agrochem #ChemJobs #chemsky 🧪
jobs.syngenta.com/job/principa...
Principal Scientist - Computational Chemistry (m/f/d)
jobs.syngenta.com
Reposted by Drug Discovery Unit, University of Dundee
dundeecityarchives.bsky.social
Another mystery #WhereisitWednesday picture for you all. Taken probably in the 1920s, this seems to be a road in Broughty Ferry, or possibly towards Monifieth. But aren't sure where it is. Do you have any ideas?
Reposted by Drug Discovery Unit, University of Dundee
Reposted by Drug Discovery Unit, University of Dundee
rsc.org
If you’re studying chemistry & anything about graduating is making you anxious – whether that’s finding a job, managing finances, or feeling generally overwhelmed – we’re here for you. ➡️8am – 8pm, Mon–Fri: call 0800 084 3451 (UK Freephone) or +44 1223 853549 (Intl): buff.ly/tCWlE7s #ChemSky #EduSky
Reposted by Drug Discovery Unit, University of Dundee
pdbeurope.bsky.social
🧪 We're beta testing - and we want your thoughts!
Try the redesigned PDBe entry pages & let us know:
🔸 What’s working?
🔸 What’s confusing?
🔸 What features do you miss?

💬 Feedback form: tinyurl.com/pdbe-beta-form

#PDBeBeta #Bioinformatics #Biochemistry #Science #UserVoice
Reposted by Drug Discovery Unit, University of Dundee
plosbiology.org
Despite a century of use in #DrugDiscovery, specialized metabolism continues to amaze. Justin Nodwell explores a @plosbiology.org study that uses a novel computational approach to uncover unsuspected functions of a compound produced by #Streptomyces 🧪 Paper: plos.io/43UVUPB Primer: plos.io/4n25bOF
Proposed biosynthetic pathway for assembly of desferrioxamines E and B. Main biosynthetic enzymes presented in bold face. DesG and DesH balance intracellular N-hydroxy-N-succinylcadaverine (HSC) and N-hydroxy-N-acetylcadaverine (HAC) concentrations by converting HSC to HAC. In the absence of DesG and/or DesH, the cells likely fail to produce sufficient levels of HAC, thereby strongly attenuating the production of DFOB. Although DesC has been shown to be able to catalyze the acetylation of N-hydroxycadaverine in vitro, the enzyme can only modestly compensate for the loss of DesH in vivo, underlining the important role played by DesG and DesH in DFOB production.
Reposted by Drug Discovery Unit, University of Dundee
cristinapujades.bsky.social
Do you want to join us to work in neurodevelopmental biology? Please apply 👇 #SEBD
Reposted by Drug Discovery Unit, University of Dundee
cenmag.bsky.social
Nominate a chemist with disabilities for C&EN's Trailblazers 2025!

Please tell us about your chemistry heroes, mentors, mentees, and inspirations—or nominate yourself.
👉 cenm.ag/nominatetrai...

#chemsky 🧪 #phdsky #academicsky #STEM #phdchat #academicchatter
C&EN's Trailblazers
Reposted by Drug Discovery Unit, University of Dundee
natrevdrugdiscov.nature.com
For readers interested in ion channels as drug targets, this Review in the May issue focuses on voltage-gated sodium channels, such as Nav1.8, the target of the first new non-opioid analgesic to be approved in decades
www.nature.com/articles/s41...
rdcu.be/enkq4
Voltage-gated sodium channels
Reposted by Drug Discovery Unit, University of Dundee
imgprague.bsky.social
🧬 Passionate about primary cilia and cell signalling?
🧫 Curious about the actin role in growth and function?
🗣️ Skilled in communication and value flexibility in your work?
Join IMG now!
www.img.cas.cz/2025/05/8654...
Reposted by Drug Discovery Unit, University of Dundee
bpernaute.bsky.social
🚨🚨#Hiring!

3 year #postdoc position open in my lab @cabd-upo-csic.bsky.social to study the interplay between DNA damage responses and #preimplantation embryo development. Fully funded by EARLYFATE #ERCCoG

📆 Apply by 23rd May 2023

🔗Details below

@sebioldev.bsky.social

Please RT!🙏
Reposted by Drug Discovery Unit, University of Dundee
unaids.org
The cuts in US funding continue to impact countries.

Read how HIV services and communities in Angola, Lao PDR, Lesotho, and South Africa are being impacted, and how governments and partners are taking urgent action protect progress and ensure continuity of care. www.unaids.org/en/impact-US...