Simona Della Valle
@dellavallesimo.bsky.social
Synthetic biologist, farming microbes for sustainability • Research Associate @ UWA • Formerly PhD @ox.ac.uk @oxengsci.bsky.social • she/her
Reposted by Simona Della Valle
Online now: Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
This study developed two simple, efficient, and rapid genome editing tools termed Self-splicing Intron-Based Riboswitch-Cas9 (SIBR-Cas9) and SIBR2.0-Cas12a, for editing the genome of the industrially relevant microbial strain Cupriavidus necator H16.…
dlvr.it
March 16, 2025 at 3:14 PM
Online now: Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
Reposted by Simona Della Valle
🚨Check out this amwesome new CRISPR tool for highly efficient genome engineering in C. necator led by @dellavallesimo.bsky.social and @eorsi.bsky.social 🔥🔥🔥
Our brand new CRISPR/Cas toolkit for genome editing of Cupriavidus necator is out🦠🧬
A joint effort w/ @dellavallesimo.bsky.social and Costas (and many more!)
Check 🧵 our long journey for developing a new state-of-the-art for the manipulation of this promising bug 1/n
www.cell.com/trends/biote...
A joint effort w/ @dellavallesimo.bsky.social and Costas (and many more!)
Check 🧵 our long journey for developing a new state-of-the-art for the manipulation of this promising bug 1/n
www.cell.com/trends/biote...
Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
This study developed two simple, efficient, and rapid genome editing tools termed
Self-splicing Intron-Based Riboswitch-Cas9 (SIBR-Cas9) and SIBR2.0-Cas12a, for editing
the genome of the industrially ...
www.cell.com
March 14, 2025 at 4:45 PM
🚨Check out this amwesome new CRISPR tool for highly efficient genome engineering in C. necator led by @dellavallesimo.bsky.social and @eorsi.bsky.social 🔥🔥🔥
Reposted by Simona Della Valle
Microbes like Cupriavidus necator naturally grow on #renewable feedstocks ♻️🧫 (CO₂, formate, hydrogen), yet their potential remains untapped due to the lack of efficient genetic tools... 1/2
www.cell.com/trends/biote...
www.cell.com/trends/biote...
March 16, 2025 at 3:40 PM
Microbes like Cupriavidus necator naturally grow on #renewable feedstocks ♻️🧫 (CO₂, formate, hydrogen), yet their potential remains untapped due to the lack of efficient genetic tools... 1/2
www.cell.com/trends/biote...
www.cell.com/trends/biote...
Our new #CRISPR toolkit for C. necator, built on SIBR-Cas technology, is now in press - an incredible collaboration with @eorsi.bsky.social, @copabio.bsky.social and many others🧪🧬⏳✂
Check out the thread below for details on genome editing + controlling gene expression by splitting a gene in two!
Check out the thread below for details on genome editing + controlling gene expression by splitting a gene in two!
Our brand new CRISPR/Cas toolkit for genome editing of Cupriavidus necator is out🦠🧬
A joint effort w/ @dellavallesimo.bsky.social and Costas (and many more!)
Check 🧵 our long journey for developing a new state-of-the-art for the manipulation of this promising bug 1/n
www.cell.com/trends/biote...
A joint effort w/ @dellavallesimo.bsky.social and Costas (and many more!)
Check 🧵 our long journey for developing a new state-of-the-art for the manipulation of this promising bug 1/n
www.cell.com/trends/biote...
Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
This study developed two simple, efficient, and rapid genome editing tools termed
Self-splicing Intron-Based Riboswitch-Cas9 (SIBR-Cas9) and SIBR2.0-Cas12a, for editing
the genome of the industrially ...
www.cell.com
March 17, 2025 at 2:39 AM
Our new #CRISPR toolkit for C. necator, built on SIBR-Cas technology, is now in press - an incredible collaboration with @eorsi.bsky.social, @copabio.bsky.social and many others🧪🧬⏳✂
Check out the thread below for details on genome editing + controlling gene expression by splitting a gene in two!
Check out the thread below for details on genome editing + controlling gene expression by splitting a gene in two!