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Silvia De Rubeis

@derubeislab.bsky.social

570 followers 680 following 140 posts

labs.icahn.mssm.edu

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Silvia De Rubeis @derubeislab.bsky.social · May 18

🧪 New paper alert!

In new work led by Adele Mossa out now in @natcomms.nature.com, we find that the #autism risk gene #DDX3X is a critical regulator of sexual dimorphisms in neuronal neurodevelopment 🧬 🧠

www.nature.com/articles/s41...

Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X - Nature Communications

Genetic mutations in the DDX3X gene are associated with a neurodevelopmental disorder primarily affecting females. Here authors show that Ddx3x mediates sexual dimorphisms during brain development at ...

www.nature.com

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Silvia De Rubeis @derubeislab.bsky.social · 9d

Congrats!

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Silvia De Rubeis @derubeislab.bsky.social · 25d

Comment to the new insights offered by this new important study from @lotsb.bsky.social and future directions 👇🏼

www.nature.com/articles/s41...

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Reposted by Silvia De Rubeis

European Journal of Human Genetics @ejhg-journal.bsky.social · Aug 26

DDX3X can cause a neurodevelopmental disorder in males. 🧬
📢 A new cohort of affected males broadens the spectrum. ⬇️

www.nature.com/articles/s41...

European Journal of Human Genetics - DDX3X-related neurodevelopmental disorder in males – presenting a new cohort of 19 males and a literature review

www.nature.com

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Silvia De Rubeis @derubeislab.bsky.social · 26d

Congrats!

Reposted by Silvia De Rubeis

Cientifico Latino, Inc. @cientificolatino.com · Sep 2

✨ Applying for fellowships?

Check out 40+ successful sample applications from:
NSF-GRFP, PD Soros, HHMI Gilliam, Ford, NIH F31 …and more!

Get inspired and strengthen your own application by learning from winners in your field.
🔗 cientificolatino.com/writing-center

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Reposted by Silvia De Rubeis

EXPeditions @expeditions.bsky.social · Aug 26

“How does a brain take shape?” Neurobiologist @bassemh.bsky.social on the embryonic cells that fold into the neural tube and become the brain.
Discover more in The Brain’s Secret.

#Biology #Neuroscience #Brain #Education #ReliableKnowledge #PublicEngagement

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Reposted by Silvia De Rubeis

The Friedman Brain Institute @sinaibrain.bsky.social · Aug 8

HAPPENING NOW! Visit the Icahn School of medicine #SURP4US Poster Session as @wellesley.edu's Kayla Quinlan, mentored by the DeRubeis Lab, presents her summer research project on “Characterizing olfactory bulb development in a mouse model of DDX3X syndrome”. @mountsinainyc.bsky.social NOT TO MISS!

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Reposted by Silvia De Rubeis

Eileen Furlong @eileen-furlong.bsky.social · Jul 30

To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Group Leader - Genome Biology Unit

Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

embl.wd103.myworkdayjobs.com

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Reposted by Silvia De Rubeis

Cientifico Latino, Inc. @cientificolatino.com · Aug 11

🎉 Big congratulations to GSMI-NYC 2022 scholar, @michae1flores.bsky.social, on being awarded the prestigious HHMI Gilliam Fellowship! 🌟 We are so proud of you leading the way for the next generation of scientists!

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Reposted by Silvia De Rubeis

Madhu Pai, MD, PhD @madhupai.bsky.social · Aug 10

A reminder that the mRNA vaccine technology saved millions of lives during the Covid pandemic and received the 2023 Nobel Prize for Medicine

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Silvia De Rubeis @derubeislab.bsky.social · Aug 7

Incredibly proud to see our alumnus Michael Flores among the 2025 Gilliam Fellows 🥹

Congratulations to Michael and all other Fellows!

HHMI @hhmi.org · Aug 7

Congratulations 2025 Gilliam Fellows and Advisors! 🎉

The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.

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Reposted by Silvia De Rubeis

Jeremy Berg @jeremymberg.bsky.social · Jun 27

New Science story about the beginnings of grant reinstatement.

www.science.org/content/arti...

NIH will reinstate 900 grants in response to court order

Projects touching on sensitive topics such as DEI had been illegally terminated, judge found

www.science.org

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Reposted by Silvia De Rubeis

Society for Neuroscience @sfn.org · Jun 19

Today, SfN joins communities across the nation in celebrating #Juneteenth — a day that honors freedom, resilience, and progress.

We celebrate the remarkable contributions of Black neuroscientists whose research has expanded our understanding of the brain and improved lives worldwide.

#neurosky

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Silvia De Rubeis @derubeislab.bsky.social · Jun 14

Congratulations!

Silvia De Rubeis @derubeislab.bsky.social · Jun 14

Congratulations!

Reposted by Silvia De Rubeis

Jeremy Berg @jeremymberg.bsky.social · Jun 13

What? Some good news on a Friday?

Parent Fellowship Notices of Funding Opportunities are up!

F30, F31, F32, F33

grants.nih.gov/grants/guide...

PA-25-422: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) PA-25-422. NI...

grants.nih.gov

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Reposted by Silvia De Rubeis

Unique @uniquecharity.bsky.social · Jun 12

Today is DDX3X Awareness Day!

12th June marks the fifth annual International DDX3X Day!

Share our expert-written guide, freely available online at bit.ly/3VlQ0D5

#DDX3X #RareChromo #GeneDisorder #ChromosomeX #AwarenessDay #Unique #FamilySupport

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Reposted by Silvia De Rubeis

MM @phdeez.bsky.social · Jun 13

the reissued NOFO for theRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) is finally published! grants.nih.gov/grants/guide...

PA-25-425: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Par...

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without N...

grants.nih.gov

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Reposted by Silvia De Rubeis

Nikki McCann Ramírez @nikkimcr.bsky.social · Jun 12

Padilla: If this is how DHS responds to a senator with a question you can only imagine what they're doing to farm workers, to cooks, to day laborers out in the Los Angeles community and throughout California.

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Reposted by Silvia De Rubeis

Rachel Maddow @maddow.msnbc.com · Jun 8

"Tanner, a chemist at the Univ. of Mississippi working to develop a novel approach for treating glioblastoma, was notified in April that the grant was terminated.

“I would like to cure brain cancer,” Dr. Tanner said. “I think that's not particularly controversial.”

www.nytimes.com/interactive/...

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant

Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

www.nytimes.com

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Reposted by Silvia De Rubeis

The Friedman Brain Institute @sinaibrain.bsky.social · Jun 2

NEW STUDY from Adele Mossa, Lauren Dierdorff, Jeronimo Lukin, Silvia De Rubeis, et al. unveils sex-specific molecular signatures when Ddx3x is missing, impacting the neuronal proteome, protein synthesis machinery & nucleoli structure. Learn More @natcomms.nature.com 👉 www.nature.com/articles/s41...

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Reposted by Silvia De Rubeis

Daniel MacArthur @dgmacarthur.bsky.social · May 24

Excited to be in Milan for #eshg2025! If you’re interested in leading analysis of large, diverse cohorts with WGS and cellular genomic data in Australia, I’d be keen to chat - we’re looking to fill a variety of senior comp bio roles: populationgenomics.org.au/careers/ #eshg25

Careers - Centre for Population Genomics

populationgenomics.org.au

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Silvia De Rubeis @derubeislab.bsky.social · May 24

Likewise, Marija! Definitely keeping in touch!

Silvia De Rubeis @derubeislab.bsky.social · May 24

Thanks Giannina for organizing this at @canacn.bsky.social. It was so much fun!

It was great seeing you and @arrudacarvalho.bsky.social again and meeting so many new friends!

@kundakoviclab.bsky.social @ivazovkic.bsky.social @walkerde.bsky.social @iordanova.bsky.social @deryasargin.bsky.social

Giannina Descalzi @descalzi.bsky.social · May 21

Join us at CAN for genomic fun!

Marija Kundakovic @kundakoviclab.bsky.social · May 21

If you are at @canacn.bsky.social , don't miss our symposium on Thurs 1:30 pm:

A genomics approach towards understanding sex differences in cognition, mental health, and neurodevelopment.

w @descalzi.bsky.social @ivazovkic.bsky.social @derubeislab.bsky.social @walkerde.bsky.social

See you there!

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