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dickretired

@dickretired.bsky.social

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Neuroscientist

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dickretired @dickretired.bsky.social · 1d

I am all for the bilogical. I think it needs to be a living thing

dickretired @dickretired.bsky.social · 2d

And what is the answer?

dickretired @dickretired.bsky.social · 11d

My oldest friend calls me Digit. Don’t you dare or I will put ICE onto you.

dickretired @dickretired.bsky.social · 12d

I had to look Loz up. It is also the name in a video game. How do you expect the old to keep up?

dickretired @dickretired.bsky.social · 13d

John mentioned this to me recentl y but I hadn’t seen it.

dickretired @dickretired.bsky.social · 13d

We agree that the aim is to produce any sequence in time and space). I also think that episodic memories of events are typically memories of sequences (i bought a ticket at the cinema booth).

dickretired @dickretired.bsky.social · 13d

But given close connections of dorsal PF with the hippocampus (PF to retrosplenial to hippocampus) the PF will also support the planning of spatial sequences.

dickretired @dickretired.bsky.social · 13d

I agree and in chapter 8 as well as the earlier book with Steve Wise I/we stress the importance of generalisation. Shima and Tanji (2007) demonstrate abstract coding for manual sequences (admittedly only a few). I only dealt with sequences in time as there was little on sequences in space.

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Reposted by dickretired

Alfred Nobel @alfrednobel.bsky.social · 14d

@vincentcostaphd.bsky.social
@dickretired.bsky.social

The functional side of it all is already completely explained by showing that we create templates. See also: @hugospiers.bsky.social

During shopping we execute the exact same template as the mouse does.
www.researchgate.net/publication/...

Reposted by dickretired

Drug Monkey @drugmonkey.bsky.social · 14d

I wonder how much basic academic science funded by the public underlies this new treatment for Huntington’s disease?

a man sitting at a table with the words it 's a lot on his face

ALT: a man sitting at a table with the words it 's a lot on his face

media.tenor.com

dickretired @dickretired.bsky.social · 14d

Not proud of the lack of training in maths. Our younger grandson is in the top 2% for maths, I am near the bottom (though my stats are ok).

dickretired @dickretired.bsky.social · 14d

In my book chapter 6 (sequences and planning). Watanabe, Duncan et al (2023) for PF neurons and goals and subgoals.. Sakamoto, Mushiake et al (2020) macaques solving a vertical maze while the authors recorded from PF neurons. Mushiake, Tanji et al PF neurons code for each step of task.

dickretired @dickretired.bsky.social · 14d

Of co urse this fits my characterisation of prefrontal in my 2021 book, thugh this did not give a mechanistic explanation. It is also consistent with what John Duncan thinks. And Mushiake et al presented macaques with exactly the problem illustrated, moving a cursor via several steps to a goal.

dickretired @dickretired.bsky.social · 14d

No they don’t get better, but I’m 82.

dickretired @dickretired.bsky.social · 14d

This looks hyper interesting; if only I could understand maths. That comes of being trained in the humanities. I am not proud of that.

dickretired @dickretired.bsky.social · 14d

On dialysis but fine.

dickretired @dickretired.bsky.social · 15d

What we don’t know is what the differences in cyto and myelo architecture mean. There are similarities between the columnar structure in different areas, but also some differences. We know this for the FEF v VI and area 46 v VI. But the microarchitecture of areas 44 and 45 needs exploring.

dickretired @dickretired.bsky.social · 15d

But we don’t have to assume a special architecture.

dickretired @dickretired.bsky.social · 15d

I didn’t mean to have replies turned off! Thanks for the information about the amount of language exposure. So children could learn like LLMs and not as Chomsky said. Presumably LLMs code for rules even though they are taught to learn the statistics of the next word?

dickretired @dickretired.bsky.social · 16d

#neuroskyence Can someone explain to me: if a huge neural net exposed to a huge corpus of language, and trained to learn the statistics of the next word, can produce excellent grammar, why can’t infants learn in the same way? Of course they are exposed to much less, but they have parental guidance.

dickretired @dickretired.bsky.social · 16d

On reading the paper I see that both circuit level theories are compatible with theories that suggest that large scale interactions are needed for awareness.

dickretired @dickretired.bsky.social · 16d

What Indon’t understand is that the evidence is that consciousness de pends o n onteracti ons between areas. This is agreed both by Tononi and Koch and by Dehaene. So in what way do either DIT or AAT promote interactions?

dickretired @dickretired.bsky.social · 17d

But the evidence you quote is for proxies in animals and there is no agreement on consciousness in animals (though personally I am happy to assume perceptual awareness because of the work by Stoerig and Cowey on macaques. Their results don’t prove it, but could point to it.

dickretired @dickretired.bsky.social · 17d

Sorry, I should have read the paper and not just lazily looked at the abstract. I thought I knew the relevant literature and clearly don’t. That comes from being retired.

dickretired @dickretired.bsky.social · 17d

I agree with many of the posts in this thread. But I don’t like the tone. It is too like X. Bluesky is meant to be a safe space in which calm discussion can take place. Of course Kimmel should not have been suspended. The large media organisations are terrified of Trump.