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Discovery Immunology @discovimmunol.bsky.social · 9d

📢 Call for Papers: Advances in Veterinary Immunology 🐾🧬

Submit original research & reviews on immune function in veterinary species, comparative immunology & One Health.

Deadline: March 2026

👉 https://bit.ly/46B1I2a
##Veterinary #Immunology #OneHealth #CFP

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Discovery Immunology @discovimmunol.bsky.social · 12d

T-cell function is tightly linked to metabolism.

CARKL regulates cytokine outputs and migration by reprogramming metabolic pathways in T cells.

Read here🔗: https://bit.ly/3XDlIh6
##TCells #Immunology #Metabolism

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Discovery Immunology @discovimmunol.bsky.social · 13d

New study shows abatacept’s effect on T cells is short-lived in vivo. Once treatment stops, immune activity rebounds quickly, important insight for #RA therapy and immune modulation. 🧬

Read more: https://bit.ly/4aDHTrm
##Immunology #TCells #Abatacept

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Discovery Immunology @discovimmunol.bsky.social · 17d

On #WorldAlzheimersDay, we highlight the role of adaptive immune cells & microbial infections in #Alzheimers disease.

Could targeting immunity offer new therapies?

Read the Open Access review 👉 https://bit.ly/4p7AnNt

#Neuroinflammation

Discovery Immunology @discovimmunol.bsky.social · 22d

New in vitro model links ‘gut-like’ dendritic cells with small intestinal organoids, revealing how epithelial–DC cross-talk shapes intestinal immune responses.

Relevant insights for #EMDS2025!

Read more🔗 https://bit.ly/45NMAPS

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Discovery Immunology @discovimmunol.bsky.social · 26d

🌿 Calling all researchers!

Submit your work to the Ecoimmunology Special Collection exploring how ecological factors shape immune systems in humans & animals. Open to lab & field studies.

More info 👉 https://bit.ly/4m0x4EW

#Ecoimmunology #Immunology

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Discovery Immunology @discovimmunol.bsky.social · 26d

Heading to #BSIInflammation2025? Check out this new study on how inflammation impacts oligodendrocyte–axon interactions and neurological function.

Read the full article by Green et al.🔗 https://bit.ly/45hoSLv

Discovery Immunology @discovimmunol.bsky.social · Sep 5

💡 RAM is key for T cell activation!

This cofactor of RNA cap methyltransferase RNMT ensures proper RNA processing, protein synthesis & T cell proliferation.

Open Access 👉 https://bit.ly/42dSN5l

#Immunology #TCells #GeneExpression

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Discovery Immunology @discovimmunol.bsky.social · Sep 5

New in vitro model links ‘gut-like’ dendritic cells with small intestinal organoids, revealing how epithelial–DC cross-talk shapes intestinal immune responses.

Relevant insights for #EMDS2025!

Read more🔗 https://bit.ly/45NMAPS

Reposted by Discovery Immunology

Oxford Academic @oxfordacademic.bsky.social · Sep 4

Looking to publish your latest veterinary immunology paper? @discovimmunol.bsky.social is curating a special collection, and your research could be perfect!

Submit to join our author community: oxford.ly/4mMMSwg

#ImmunoSky

Call for Papers: Advances in Veterinary Immunology

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Discovery Immunology @discovimmunol.bsky.social · Sep 4

Fever isn’t just a symptom, it's a window into immunity.

Maloney et al. show how temperature fluctuations, from tissues to T cell mitochondria, shape immune responses. Rising global temps make this research more critical than ever. 🔬🌡️

https://bit.ly/4cZ8gu7

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Discovery Immunology @discovimmunol.bsky.social · Sep 3

🐾 Calling veterinary immunologists!

Share your research on immune systems across species, vaccines, and One Health in our Advances in Veterinary Immunology collection led by Prof. Jayne Hope.

📅 Submit by March 2026: https://bit.ly/46lLw5W

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Discovery Immunology @discovimmunol.bsky.social · Aug 29

🧬💉 DNA vaccines for flu? A new study tests a Doggybone™ DNA platform, finding that including neuraminidase (NA) adds extra protection.

Another step toward broader, faster, more adaptable vaccines.

🔗 https://bit.ly/4p4bHpk
##VaccinesWork #ImmunisationAwarenessMonth

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Discovery Immunology @discovimmunol.bsky.social · Aug 28

💉 Alum has powered vaccines for nearly a century, but how it boosts immunity is still being unraveled.

From DNA sensing to inflammasomes, new insights into its mechanism could guide the next generation of vaccine adjuvants.

🔬 #NationalImmunisationMonth

🔗 https://bit.ly/3UQM5hB

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Discovery Immunology @discovimmunol.bsky.social · Aug 22

Cell migration matters: stem-like CD8 T cells travel between tumour and peripheral niches, shaping both local control and systemic memory against cancer.

🔗 https://bit.ly/45SuFq3

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Discovery Immunology @discovimmunol.bsky.social · Aug 20

🚨 T cells and bacterial microbiota at skin & gut barriers: how epithelial interactions shape immunity, tolerance, and tissue repair.

Open Access: https://bit.ly/4mQyQcC

#Immunology #Microbiome #TCells

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Discovery Immunology @discovimmunol.bsky.social · Aug 19

Immunotherapy is emerging as a lifeline for patients with brain metastases.

This review explores how the brain’s specialized immune environment, lymphatic drainage & systemic immunity impacts treatment.

🔗 https://bit.ly/4oKb5ET

Immunotherapy in the context of immune-specialized environment of brain metastases graphical abstract

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Discovery Immunology @discovimmunol.bsky.social · Aug 16

🐶🐄 Calling veterinary immunology researchers!

Share your latest work on immune systems, vaccines, and One Health in our Special Collection: Advances in Veterinary Immunology.

Submit by Mar 2026.
##VetImmunology #OneHealth

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Discovery Immunology @discovimmunol.bsky.social · Aug 14

Maskell et al. uncover how growth factors & cytokines fuel transmissible Tasmanian devil cancers.

PDGFR boosts tumour spread; TGFβ triggers EMT-like shifts.

Findings could guide vaccines & therapies to save this endangered species.

🔗 https://bit.ly/47f6uob #IVIS2025

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Discovery Immunology @discovimmunol.bsky.social · Aug 13

Attending #IVIS2025? 🐷🫁

New research shows airway-resident memory T cells in young pigs aren’t just long-lived, they’re replenished via proliferation, likely in the lung interstitium before migrating to the airways.

Dynamic immunity in action! 🔬

https://bit.ly/3RRINsU

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Reposted by Discovery Immunology

British Society for Immunology @britsocimm.bsky.social · Aug 12

From livestock to wildlife, veterinary immunology is key to understanding the immune system. 🐷🐓🐑

Our @discovimmunol.bsky.social highlights for #IVIS2025 showcase research changing how we understand immunity across species.

Read here 👉 https://bit.ly/41BQkRO
##VeterinaryImmunology #OpenAccess

Photo grid of soay sheep%2C tasmanian devil%2C chickens and a young pig

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Discovery Immunology @discovimmunol.bsky.social · Aug 11

How do ILC1s help fight cancer, and what role does PD-1 play?

This open access review breaks down the complexity of ILC1 subsets and their checkpoint regulation.

📖 https://bit.ly/4fnU0N0

#ILC1 #CancerImmunology #PD1

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Discovery Immunology @discovimmunol.bsky.social · Aug 8

Skariah et al. explore the dual nature of IL-15, essential for NK and tissue-resident T cell homeostasis at low levels, but a potent driver of inflammation and autoimmunity when upregulated.

🔗 Open access: https://bit.ly/3JqM8Ow
##Immunology

Discovery Immunology @discovimmunol.bsky.social · Aug 7

IL-21 shapes γδ T-cell function in the gut 🧬
New findings show IL-21-conditioned Vγ9/Vδ2 T-cells promote IL-10 expression in CD4+ T-cells, surpassing monocytes/DCs.

Implications for mucosal immunity & IBD therapy.

📖 https://bit.ly/4k8cLoX

#Immunology

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Discovery Immunology @discovimmunol.bsky.social · Aug 5

🧬 Spermidine suppresses dendritic cell activation by preserving mitochondrial function through eIF5A hypusination, limiting T cell interactions and shaping immune responses.

Could this pathway offer new insights into immune regulation or evasion? 👉 https://bit.ly/4ooi8mE
##Immunology

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