dmichonneau.bsky.social
David Michonneau
@dmichonneau.bsky.social
52 followers 120 following 6 posts
MD, PhD, hematologist @hopitalsaintlouis.bsky.social Professor of hematology @upcite.bsky.social @INSERM @institut-leucemie.bsky.social UMR1342 https://www.institut-leucemie.fr/linstitut-de-la-leucemie-recherche/immunologie-translationnelle/
www.institut-leucemie.fr
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dmichonneau.bsky.social
David Michonneau @dmichonneau.bsky.social · Jul 10
doi.org/10.1084/jem....

Great collaboration with the group of Robert Zeiser linking microbiota-derived metabolites and central nervous system GVHD
Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD
In this study, we report that microbiota depletion exacerbates acute graft-versus-host disease in the central nervous system, driven by microglial activati
doi.org
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dmichonneau.bsky.social
David Michonneau @dmichonneau.bsky.social · Jun 19
www.nature.com/articles/s41...
Diet outperforms microbial transplant to drive microbiome recovery in mice - Nature
Experiments in mouse models show that proper recovery of the intestinal microbiota following depletion, with or without faecal microbiota transplant therapy, is dependent on syntrophic interactions th...
www.nature.com
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dmichonneau.bsky.social
David Michonneau @dmichonneau.bsky.social · Apr 16
Great collaboration with Robert Zeiser @institut-leucemie.bsky.social @upcite.bsky.social @ap-hp.bsky.social @insermpresse.bsky.social Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey @springernature.com @BMT journal

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Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey
Bone Marrow Transplantation - Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey
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dmichonneau.bsky.social
David Michonneau @dmichonneau.bsky.social · Apr 1
Happy to share our last paper, published with @springernature.com in @BMTjournal, about the French experience with belumosudil in the treatment of steroid-resistant cGvHD. Best ORR 57.4% including 14.7% of CR in patients who previously received at least 2 LOT
rdcu.be/efZg9
Efficacy and safety of belumosudil for treatment of cGVHD: multicenter retrospective analysis of the French cohort of the compassionate use program, on behalf of the French Society of Bone Marrow Transplantation and Cellular Therapy
Bone Marrow Transplantation - Efficacy and safety of belumosudil for treatment of cGVHD: multicenter retrospective analysis of the French cohort of the compassionate use program, on behalf of the...
rdcu.be
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dmichonneau.bsky.social
David Michonneau @dmichonneau.bsky.social · Feb 14
Congratulations to Sophie Le Grand for her very interesting paper in Hemasphere about the role of HLA evolutionary divergence score to predict outcome of prophylactic donor lymphocyte infusion after alloHSCT

doi.org/10.1002/hem3...
HLA evolutionary divergence score after donor lymphocyte infusion following allogeneic hematopoietic stem cell transplantation
Donor lymphocyte infusion (DLI) prevents acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) relapses following hematopoietic stem cell transplantation. Given the life-threatening toxiciti....
doi.org
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dmichonneau.bsky.social
David Michonneau @dmichonneau.bsky.social · Jan 20
Systems-level immunomonitoring in children with solid tumors to enable precision medicine: Cell www.cell.com/cell/fulltex...
Systems-level immunomonitoring in children with solid tumors to enable precision medicine
In a population-based cohort of 191 children with diverse solid tumors, systems-level analyses unravel immune variation with age and tumor type and provide a reference for future precision immunothera...
www.cell.com
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