dorisloh.bsky.social
@dorisloh.bsky.social
Zhang Y, Li X-H, Peng P, Qiu Z-H, Di C-X, Chen X-F, et al. RUNX2 phase separation mediates long-range regulation between osteoporosis-susceptibility variant and XCR1 to promote osteoblast differentiation. Adv Sci (Weinh). 2025;12:e2413561.
advanced.onlinelibrary.wiley.com/doi/10.1002/...
RUNX2 Phase Separation Mediates Long‐Range Regulation Between Osteoporosis‐Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation
A GWAS intergenic SNP (rs4683184) acts as an enhancer, altering the binding affinity of the transcription factor RUNX2 and resulting in changes in XCR1 expression and osteoblast differentiation. RUNX....
advanced.onlinelibrary.wiley.com
April 21, 2025 at 2:11 PM
Thank you Allan!
April 9, 2025 at 7:42 PM
Very happy to connect with you on Bluesky. I have been undecided over the switch. It took me quite a few years to build up a modest following at X. I don't mind getting verified for credibility. I do mind having to pay a monthly fee for the privilege.
April 9, 2025 at 7:41 PM