What if you could tap into the computational power of thousands of volunteers worldwide to accelerate your drug discovery efforts? That’s what we’ve done by integrating alchemiscale and @openfree.energy with Folding@Home!

Read more: alchemiscale.org/advancements...

#openscience #drugdiscovery

Proud to have shared some of our recent work at the 2025 Workshop on Free Energy Methods in Boston!

Our poster detailed the engineering approach we took to enable large-scale computation of alchemical binding free energies via alchemiscale (alchemiscale.org) and Folding@Home (foldingathome.org).

Do you use alchemiscale in production? Or would you like to?

We recently shared a perspective on the progress of the project, where we're currently focused, and the opportunities we see for advancement in 2025:

alchemiscale.org/opportunitie...

Let us know what you think! #drugdiscovery #oss

Gave an invited talk a few weeks back at Memorial Sloan Kettering Cancer Center on alchemiscale (github.com/openforcefie...), and how we're working to scale out alchemical free energy calculations to support open data antiviral discovery for ASAP Discovery (asapdiscovery.org) via Folding@Home.