Rajendra Singh Negi
@dr-rajendra-s-negi.bsky.social
Postdoctoral researcher Manning Group @manningresearch.bsky.social . Completed PhD from Forschungszentrum Jülich, University of Cologne.
Reposted by Rajendra Singh Negi
❗PREPRINT ALERT❗
doi.org/10.64898/202...
The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.
doi.org/10.64898/202...
The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.
December 17, 2025 at 5:20 PM
❗PREPRINT ALERT❗
doi.org/10.64898/202...
The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.
doi.org/10.64898/202...
The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.
Reposted by Rajendra Singh Negi
How do sparse mesenchymal cells, with unique stellate arms spanning large gaps between cells, maintain their network while still flowing during development? In our new preprint we describe the avian PSM as a fluid under tension and develop new theory to explain it: www.biorxiv.org/content/10.6...
Sparse mesenchymal cell networks as a fluid under tension
Sparse mesenchymal cellular networks are ubiquitous across animals, shaping both embryonic and adult structures through dynamic interactions with epithelia. Yet, the physical principles underlying the...
www.biorxiv.org
December 12, 2025 at 1:28 PM
How do sparse mesenchymal cells, with unique stellate arms spanning large gaps between cells, maintain their network while still flowing during development? In our new preprint we describe the avian PSM as a fluid under tension and develop new theory to explain it: www.biorxiv.org/content/10.6...
Reposted by Rajendra Singh Negi
Kelly Aspinwall, Tyler Hain, M. Lisa Manning: Rigidity and mechanical response in biological structures https://arxiv.org/abs/2508.18432 https://arxiv.org/pdf/2508.18432 https://arxiv.org/html/2508.18432
August 27, 2025 at 6:43 AM
Kelly Aspinwall, Tyler Hain, M. Lisa Manning: Rigidity and mechanical response in biological structures https://arxiv.org/abs/2508.18432 https://arxiv.org/pdf/2508.18432 https://arxiv.org/html/2508.18432
Reposted by Rajendra Singh Negi
Villeneuve, C., Hashmi, A., ... & Wickström, S. A. (2024). Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture. Nature Cell Biology #EpithelialMechanics www.nature.com/articles/s41...
April 21, 2025 at 11:01 AM
Villeneuve, C., Hashmi, A., ... & Wickström, S. A. (2024). Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture. Nature Cell Biology #EpithelialMechanics www.nature.com/articles/s41...
Reposted by Rajendra Singh Negi
Biology makes materials far more complex that what we can achieve ourselves. It often does this with small parts that come together to assemble into larger structures with defined sizes. Here is a theoretical contribution to solving this problem, funded by the NSF.
journals.aps.org/prl/abstract...
journals.aps.org/prl/abstract...
Geometrically Frustrated, Mechanical Metamaterial Membranes: Large-Scale Stress Accumulation and Size-Selective Assembly
We study the effect of geometric frustration on dilational mechanical metamaterial membranes. While shape frustrated elastic plates can only accommodate nonzero Gaussian curvature up to size scales th...
journals.aps.org
February 23, 2025 at 11:14 PM
Biology makes materials far more complex that what we can achieve ourselves. It often does this with small parts that come together to assemble into larger structures with defined sizes. Here is a theoretical contribution to solving this problem, funded by the NSF.
journals.aps.org/prl/abstract...
journals.aps.org/prl/abstract...