Lightnews — Scholar-powered news

Esther Pearl @drejpearl.bsky.social · 15d

The @nc3rs.bsky.social's Experimental Design Assistant (EDA) is back online following planned maintenance. Thank you for your patience.

Esther Pearl @drejpearl.bsky.social · 15d

🚨⚠️ The @nc3rs.bsky.social's Experimental Design Assistant will be offline for planned maintenance today (Tuesday 23 September) from 4pm BST. Please ensure your work is saved before 4pm. We apologise for any inconvenience caused and will notify you when the EDA is back online. ⚠️🚨

Esther Pearl @drejpearl.bsky.social · 15d

🚨⚠️ The @nc3rs.bsky.social's Experimental Design Assistant will be offline for planned maintenance today (Tuesday 23 September) from 4pm BST. Please ensure your work is saved before 4pm. We apologise for any inconvenience caused and will notify you when the EDA is back online. ⚠️🚨

Esther Pearl @drejpearl.bsky.social · 19d

🚨⚠️The @nc3rs.bsky.social's Experimental Design Assistant (EDA) will be offline for planned maintenance on Tuesday 23 September from 4pm BST. We anticipate it will be back online by the morning of Wednesday 24 September. We apologise for any inconvenience caused.⚠️🚨

Reposted by Esther Pearl

The Learning Curve (Development) Ltd @tlcdevelopment.bsky.social · 23d

Spaces still available for this excellent scientific webinar later this week - register via link below 👇

NC3Rs @nc3rs.bsky.social · 27d

Join us next week to learn more about misconceptions around sex-inclusive research and how the Sex Inclusive Research Framework can be used by scientists, ethical review bodies and funders: nc3rs.org.uk/events/tackl...

📅 18 September, 15.00 – 16.00

📜 One hour of continuing professional development

A black mouse with a litter of pups in a laboratory cage.

1 2

Reposted by Esther Pearl

NC3Rs @nc3rs.bsky.social · 27d

Join us next week to learn more about misconceptions around sex-inclusive research and how the Sex Inclusive Research Framework can be used by scientists, ethical review bodies and funders: nc3rs.org.uk/events/tackl...

📅 18 September, 15.00 – 16.00

📜 One hour of continuing professional development

1 3 3

Esther Pearl @drejpearl.bsky.social · 29d

Interested in tools to help teach experimental design? Is your institution part of the UKRN Open Research Programme? www.ukrn.org/partner-inst...

👇 Register for the online workshop on how to use, and teach others to use, the Experimental Design Assistant (EDA). Registrations close 17 September. 👇

Reposted by Esther Pearl

NC3Rs @nc3rs.bsky.social · Sep 3

We are supporting in-person training workshops to promote the use of skin swabbing as a refined approach for genotyping zebrafish.
🐟 Suitable for technical staff and researchers
🤝 Personalised support in small groups
📍 Delivered at your facility (UK only)

Find out more: nc3rs.org.uk/training-wor...

A zebrafish is held in a hand net and swabbed.

2 6

Esther Pearl @drejpearl.bsky.social · Sep 1

The @nc3rs.bsky.social contingent has ARRIVEd in Brazil for #WC13. Yesterday kicked off with the opening ceremony. Today join me in session 118: Ethics in action. I will be highlighting resources to support reduction and how ethical review bodies can use them.

3

Reposted by Esther Pearl

NC3Rs @nc3rs.bsky.social · Aug 26

⏳ Registration closing on Thursday 28 August!

Interested in driving the uptake and impact of 3Rs models and technologies through cross sector collaborations? Join us and the BBSRC in London on September 12 as we launch our new joint funding initiative.

Find out more: nc3rs.org.uk/events/nc3rs...

Icons representing NC3Rs Networks in oncology, cardiovascular science and new approach methodologies for safety assessment.

2 3

Esther Pearl @drejpearl.bsky.social · Aug 22

Now that the 20th International Xenopus conference is over it is time to rest my geeky earrings. I had a great time catching up with people and discussing welfare research priorities. Interested in the amphibian welfare webinars I mentioned? Here’s the link: nc3rs.org.uk/3rs-resource... #IXC25

1 1 3

Esther Pearl @drejpearl.bsky.social · Aug 19

Having some great conversations about Xenopus welfare at the 20th International Xenopus conference. Also got to wear my Xenopus earrings!! #IXC25

3

Esther Pearl @drejpearl.bsky.social · Aug 17

The @nc3rs.bsky.social stand is all set up at #IXC25. Looking forward to a great meeting!!

3

Esther Pearl @drejpearl.bsky.social · Aug 17

Caroline Beck @frogsquisher.bsky.social · Aug 17

Hey! Any #xenopus folk at IXC25 in Portsmouth? Use #IXC25 in your posts, and let us know how it’s going!!

1

Reposted by Esther Pearl

NC3Rs @nc3rs.bsky.social · Aug 4

Looking for support to teach experimental design? Join our online workshop with @ukrepro.bsky.social on using the Experimental Design Assistant (EDA) to plan rigorous, reproducible animal studies.

📅 13 November, 10.00 – 16.00 (GMT)
❗ Registration closes: 17 September
👉 nc3rs.org.uk/events/ukrn-...

2 1

Esther Pearl @drejpearl.bsky.social · Aug 5

A recent study showed more than half of publications using animal models of neurological disorders involved pseudoreplication (doi.org/10.1186/s132...). Avoid pseudoreplication - use the EDA to help you identify your experimental unit accurately: eda.nc3rs.org.uk/experimental...

Experimental unit | NC3Rs EDA

How to identify the experimental unit in an in vivo experiment

eda.nc3rs.org.uk

1 2

Esther Pearl @drejpearl.bsky.social · Aug 4

Are you looking for something to help you teach experimental design? Also at a @ukrepro.bsky.social Open Research partner institution (www.ukrn.org/partner-inst...)? Join us and learn how to the EDA can help!

2 1

Esther Pearl @drejpearl.bsky.social · Jul 23

Want a bit of extra help designing your next in vivo experiment? Join me tomorrow for a demonstration of the @nc3rs.bsky.social Experimental Design Assistant: nc3rs.org.uk/3rs-resource...

Virtual demonstrations of the Experimental Design Assistant

Learn how our online EDA tool can help you plan rigorous experiments.

nc3rs.org.uk

4

Esther Pearl @drejpearl.bsky.social · Jul 17

🎉🥳 Happy Birthday ARRIVE 2.0! 🥳🎉 ARRIVE goes further than reporting guidelines, check out the free resources to help us improve the way we plan, conduct and report animal research! 👇

NC3Rs @nc3rs.bsky.social · Jul 16

ARRIVE 2.0 turns five! Since we launched our updated guidelines in July 2020, we have developed a suite of resources to embed transparency and reproducibility throughout the research lifecycle, from planning to peer review: arriveguidelines.org/resources

1

Esther Pearl @drejpearl.bsky.social · Jul 14

Ever been frustrated by antibodies not working they way you think they should? This year's 3Rs prize winners 🏆 tested over 600 antibodies leading to 73 inadequately performing antibodies being withdrawn from the market. Find out more on Wednesday 23 July 👇

NC3Rs @nc3rs.bsky.social · Jun 30

A scalable system to assess antibody performance and build confidence in recombinant reagents to replace animal-derived antibodies has won this year's International 3Rs Prize, sponsored by GSK: nc3rs.org.uk/news/buildin...

Photographs of the three winners of the NC3Rs International 3Rs Prize. Left to right: Dr Riham Ayoubi, Dr Peter McPherson and Dr Carl Laflamme.

Esther Pearl @drejpearl.bsky.social · Jun 5

The Medical Research Council want to know about the impact of their policy on embedding diversity into research design.

Survey closes 13 June, don't miss the opportunity to have your say! 👇

NC3Rs @nc3rs.bsky.social · Jun 5

Help shape MRC support for researchers and reviewers implementing the requirement to use female and male animals in preclinical research – take their survey: engagementhub.ukri.org/mrc-peg/edd5...

MRC Diversity in research design: assessing the impact of the policy on researchers and reviewers

Reposted by Esther Pearl

NC3Rs @nc3rs.bsky.social · Jun 5

The Sex Inclusive Research Framework developed by an expert working group (including members of the NC3Rs team) is available to help researchers and grant reviewers implement the policy in grant proposals: www.nature.com/articles/s41...

The Sex Inclusive Research Framework to address sex bias in preclinical research proposals - Nature Communications

In preclinical research, there is a persistent sex bias where research is conducted with a single sex. Here, the authors present a Sex Inclusive Research Framework that provides a traffic light classi...

www.nature.com

1 1

Reposted by Esther Pearl

NC3Rs @nc3rs.bsky.social · Jun 5

Help shape MRC support for researchers and reviewers implementing the requirement to use female and male animals in preclinical research – take their survey: engagementhub.ukri.org/mrc-peg/edd5...

1 1 1

Esther Pearl @drejpearl.bsky.social · Apr 24

Use the online tool and receive a report regarding the sex inclusiveness of your research: openinnovation.astrazeneca.com/preclinical-...

Sex Inclusive Research Framework | Open Innovation

Enhance research integrity with our Sex Inclusion Framework, a justifiable tool promoting transparency for researchers and evaluators in sex-inclusive studies.

openinnovation.astrazeneca.com

Esther Pearl @drejpearl.bsky.social · Apr 24

Writing or assessing in vivo study designs? Use the Sex Inclusive Research Framework and supporting guidance to get a “traffic light” indicator of whether a proposal has appropriately considered sex inclusion or is at risk of sex bias www.nature.com/articles/s41...

1 4

Esther Pearl @drejpearl.bsky.social · Feb 26

Interested in improving your experimental design? The @nc3rs.bsky.social Experimental Design Assistant can help you design rigorous experiments. Our next live demonstration is Wednesday 5 March, 4-6pm GMT. nc3rs.org.uk/3rs-resource...

Virtual demonstrations of the Experimental Design Assistant

Learn how our online EDA tool can help you plan rigorous experiments.

nc3rs.org.uk

3 4