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Sam "The Mug Guy" Horrell

@drhorrell.bsky.social

940 followers 1.5K following 260 posts

Scientist 🧑‍🔬, structural biologist 🧬, X-ray Crystallographer 💎, Synchrotron Mug Enthusiast ☕, D&D 🎲 and MTG player 🧙, bird dad to Nori and Kili 🦜🦜 He/Him

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Sep 4

All three are adorable thanks 🙂

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Sep 4

Today is my birthday, please send pet pictures!

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 26

Finally, a detector suitable for the new SynchroGnome beamlines. A giant leap forward in tiny science.

#ROD10atECM #ECM

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 26

I don't have a Crystallography themed hat, so I guess I need to get one made out of something edible.

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 26

Why would we bother guessing anything else?

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 25

It's actually in P 21 21 21, but we can still meet up for that beer if you spot me at the conference.

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 25

Who are you wagering? Becuase I know the answer already 😉

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 25

Disappointingly it was P21 21 21.

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 25

Made it to Poznan for the European Crystallography Meeting. Looking forward to presenting at the Science Slam on Thursday with the help of my cat Rosalind.

#Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 20

Top notch pun work. Truly immaculate.

a man with a beard is wearing a crown and saying you bow to no one .

ALT: a man with a beard is wearing a crown and saying you bow to no one .

media.tenor.com

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 20

I don't want to alarm anyone, but I think my electron density might be haunted.

💎👻💀

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Aug 11

Said goodbye to the @dectris.bsky.social Pilatus 6M the other day with one last #DetectorSelfie featuring beamline scientist Sofia.

Collected some data to 0.87 A to give it a proper send off.

Not sure how many images it has taken on I24 but it is very deserving of a rest.

2 people, a woman wearing glasses and a man with a beard, taking a picture in the reflective surface of a photon counting detector.

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Jun 19

Protein structure or #Minecraft Creeper?

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Jun 13

Taking bets on if this is crystalline or not. We'll find out next week on @diamondlightsource.bsky.social's VMXm next week with the help of @adamcrawshaw.bsky.social.

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · Jun 5

The electron microscope can't believe you just said that.

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 29

After 2 weeks of antibiotics twice a day Nori (left) now has a clean bill of health.

Kili (right) is clearly pleased about this too.

A light yellow and grey cockateil and a dark grey peid cockateil put their heads together. One has their beak wide open. Both have very orange cheeks.

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 22

I was minding my own business watching a music video when suddenly I see @thewarningarmy.bsky.social have managed to crystallise themselves. So I thought I'd see if they diffract, and they do!

#Crystallography #TheWarning #Crystal #Diffraction

A regular repeating pattern of Ale, Pau, and Danny from the rock band The Warning. Effectively forming a 2D crystal of the band members.

$The reulsting diffraction pattern of the crystallised members of the warning. A Grey background with white spots in a regular repeating pattern.$

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 16

Naturally

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 15

If this #crystal space group isn't P3 or P6 I'll eat my #crystallography hat.

It also reminds me of a tiny allen key.

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 8

I don't see a major and a minor groove, and there are fewer that 4 bases per turn.

Reposted by Sam "The Mug Guy" Horrell

RCSB Protein Data Bank @rcsbpdb.bsky.social · May 4

Changes in PDB IDs are coming that will require use of PDBx/mmCIF file format... will you be ready? #MayThe4th
Resources are available to help: www.wwpdb.org/docume...

Him: Structures in PDB format
Her: Do you mean mmCIF and not deprecated format, right?
Him:
Her: RIGHT?

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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 4

Happy #StarWars day from Nori and Kili. May the fourth be with you.

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 2

Pretty successful draft at the local game store. Won the event and got a chonky dragon.

#MTG #MagicTheGathering

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 1

Blue copper crystals on a silicon chip.

A black silicon chip with regular etched square holes covered in blue/purple crystals.

Sam "The Mug Guy" Horrell @drhorrell.bsky.social · May 1

New paper out today on a cyclic peptide which interacts with CD59, a protein that inhibits the complement mediated membrane attack complex.

Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge.

onlinelibrary.wiley.com/doi/abs/10.1...

Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity

CD59 is an immunomodulatory cell surface receptor associated with human disease. Despite its importance in complement regulation and bacterial pathogenesis, CD59 remains a challenging therapeutic tar....

onlinelibrary.wiley.com