Lucy MacDonald
@drlucymac.bsky.social
140 followers 86 following 4 posts
Research Associate at School of Infection and Immunity, University of Glasgow 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Mapping macrophage & DC niches with single cell spatial transcriptomics 🔬🧭
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drlucymac.bsky.social
The proudest supervisor ever!! No surprise our Jack is a superstar 🌟🌟🌟
dom-somma.bsky.social
Congrats to our PhD student Jack Frew for the poster prize 🥳🥳!!

@drlucymac.bsky.social #EMDS2024
drlucymac.bsky.social
Highlights
• Tolerogenic AXL+ DC2s reside beneath the healthy synovial lining
• iDC3s populate RA hyperplastic lining, activating CCL5 Tem and/or Tph cells
• CCR7+ DC2s in sublining lymphoid niches in RA, interacting with naive T cells
• blood DC3s signature predicts RA flare
drlucymac.bsky.social
So happy to (finally!!) announce that our paper studying synovial tissue dendritic cells in joint health and rheumatoid arthritis is now out in Immunity! 🚨 doi.org/10.1016/j.im...