Michael P Ryan
drmichaelpryan.bsky.social
Michael P Ryan
@drmichaelpryan.bsky.social
Associate Professor, Dept of Chemical Sciences, University of Limerick. ORCID: 0000-0002-0489-0579. Likes Bacteria and their Mobile Genetic Elements. All views my own.
Every generation feels the world is on fire but the world really is on fire
November 16, 2025 at 12:35 PM
And yet ... crickets chirping...
who.int WHO @who.int · Oct 15
Between 2018–2023, antibiotic resistance increased in over 40% of the pathogen–antibiotic combinations monitored, with an average annual rise of 5–15%.

Resistance is highest in the WHO South-East Asian & Eastern Mediterranean Regions, where 1 in 3 reported infections were resistant 👉 bit.ly/438Ta1u
October 16, 2025 at 7:24 AM
Reposted by Michael P Ryan
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
July 23, 2025 at 7:35 AM
Shocking....(Completely obvious for anyone that has tried to use it for anything but the simplest task)
Reporter: The FDA has a new AI tool that's intended to speed up drug approvals. But several FDA employees say the new AI helper is making up studies that do not exist. One FDA employee telling us, 'Anything that you don't have time to double check is unreliable. It hallucinates confidently'
July 23, 2025 at 8:34 PM
Reposted by Michael P Ryan
New manuscript from the group

'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'

www.biorxiv.org/content/10.1...

/1
IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium
pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium , but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of t...
www.biorxiv.org
July 17, 2025 at 8:39 AM
Reposted by Michael P Ryan
As Ireland’s Second One Health National Action Plan on AMR draws to a close, the Microbiology Society has published a new report highlighting how Ireland’s microbiology community is tackling AMR and what needs to happen next. #AMR #KnockingOutAMR
July 16, 2025 at 12:03 PM
"Why are aren't there new 'antibiotics'?"👇
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
May 14, 2025 at 4:32 PM
Reposted by Michael P Ryan
Do you live in or near Maynooth? Are you interested in science? Do you want to be a part of a free annual global science event?

Then come along to Pint of Science May 19 and 21 in Maynooth

See details here: pintofscience.ie/events/Mayno... @pintofscienceie.bsky.social @pintsworld.bsky.social
Maynooth events
Maynooth scientists and researchers share their discoveries with you
pintofscience.ie
May 7, 2025 at 6:53 PM
April 26, 2025 at 3:17 PM
Reposted by Michael P Ryan
Looking to appoint a PhD candidate with background in Microbiology, Biochemistry, Biotechnology or related field to work on discovery of infection combatting therapeutics in marine sponge-associated bacteria. Closing date 31st May 2025. International applications welcomed!🌎
Four year fully funded PhD studentship: Bioprospecting Marine Sponge Streptomyces for Novel Anti-Virulence Therapeutics at Trinity College Dublin on FindAPhD.com
PhD Project - Four year fully funded PhD studentship: Bioprospecting Marine Sponge Streptomyces for Novel Anti-Virulence Therapeutics at Trinity College Dublin, listed on FindAPhD.com
www.findaphd.com
April 25, 2025 at 3:16 PM
Reposted by Michael P Ryan
Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩
Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭!
Please visit my lab's webpage for details about the position and how to formally apply.
April 25, 2025 at 4:15 PM
Reposted by Michael P Ryan
www.nature.com/articles/s41...
In collaboration with Andrew Lang and Alison Buchan, we just published a review on the complex and sometimes convoluted interactions and evolutionary relationships among bacterial mobile genetic elements.
#phage #plasmid #evolution #bacteria #plasmidbiology #MGE
Interactions and evolutionary relationships among bacterial mobile genetic elements - Nature Reviews Microbiology
In this Review, Lang and colleagues present an overview of the current knowledge landscape regarding mobile genetic elements in bacteria, with a focus on their evolutionary relationships and interacti...
www.nature.com
March 11, 2025 at 1:12 PM
Reposted by Michael P Ryan
New online! Interactions and evolutionary relationships among bacterial mobile genetic elements
Interactions and evolutionary relationships among bacterial mobile genetic elements
Nature Reviews Microbiology, Published online: 11 March 2025; doi:10.1038/s41579-025-01157-yIn this Review, Lang and colleagues present an overview of the current knowledge landscape regarding mobile genetic elements in bacteria, with a focus on their…
www.nature.com
March 11, 2025 at 1:14 PM
Reposted by Michael P Ryan
The International Society for Plasmid Biology and other Mobile Genetic Elements are finally in Bluesky!! 😎😎😎
March 11, 2025 at 2:21 PM
Who could have possibly foreseen this? (This is only the beginning)

Texas measles outbreak grows to 90 cases, worst level in 30 years www.theguardian.com/us-news/2025...
Texas measles outbreak grows to 90 cases, worst level in 30 years
Epicenter of latest outbreak had one of state’s highest immunization exemption rates for 2023-24 school year
www.theguardian.com
February 22, 2025 at 9:21 PM
Reposted by Michael P Ryan
I'm delighted to announce that the 2025 @microbiologysociety.org meeting on "Understanding and predicting microbial evolutionary dynamics" will be held in Liverpool 26-27 November 2025! Abstract submission will open soon... #microsky 🧪🧫🦠 microbiologysociety.org/event/societ...
Understanding and predicting microbial evolutionary dynamics - 2025 meeting
microbiologysociety.org
February 18, 2025 at 9:50 AM
Better late then never I suppose....
February 15, 2025 at 12:33 PM
Many thanks to Regeneron for a lovely day at the Regeneron College Awards for students of the Industrial Biochemistry and Chemical and Biochemical Engineering of ChemSci UL.
@unioflimerick.bsky.social
February 13, 2025 at 1:52 PM
Reposted by Michael P Ryan
Biopharma companies and CEOs are keeping their heads down at their own peril. They should speak up about what’s happening to the NIH and other science agencies before it’s too late.

Silence gives consent. And no one should consent to this.
Stand Up And Be Counted
www.science.org
February 12, 2025 at 4:45 PM
"Studying history is a waste of time" I remember being told this when studying it in school. It was wrong then and is absolutely wrong now.

www.thetimes.com/article/a7ce...
Gen Z doubts about democracy laid bare in ‘worrying’ survey
More than half believe the UK should be a dictatorship and there’s a stark gender divide over equality, research for Channel 4 shows
www.thetimes.com
January 26, 2025 at 8:09 PM
Spot of News...
January 20, 2025 at 1:23 PM
Reposted by Michael P Ryan
We're looking for an Assitant Professor in Microbiology to join us @tcdgenmicro! Come and join our growing team.
www.tcd.ie/microbiology...
www.tcd.ie/hr/vacancies/ Job ID: 037876. Closes 31st January
Research Groups - Microbiology | Trinity College DublinmenusearchSearchmenu
www.tcd.ie
December 2, 2024 at 4:43 PM