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dryak.mstdn.science.ap.brid.gy
DrYak
@dryak.mstdn.science.ap.brid.gy
58 followers 6 following 140 posts
Medical Doctor and Bioinformatician

[bridged from https://mstdn.science/@dryak on the fediverse by https://fed.brid.gy/ ]
Posts Replies Media Videos
Reposted by DrYak
jik.federate.social.ap.brid.gy
This is your periodic reminder that when posting a link of any sort you should include at least a sentence or two describing what it's about, because many fediverse apps (including e.g. the Mastodon web app) don't display useful previews for many types of links.
Be polite: don't make people […]
Original post on federate.social
federate.social
March 24, 2025 at 2:53 PM
Reposted by DrYak
petersuber.fediscience.org.ap.brid.gy
I'm sympathetic to #NIH-funded authors who want to publish in #APC-based #openaccess journals and can't find the money to pay the APCs. But it's false to say that they must publish in those journals, in any other APC-based OA journals, or even in OA journals. Shame on _Inside Higher Ed_ leaving […]
Original post on fediscience.org
fediscience.org
December 6, 2025 at 8:10 PM
Reposted by DrYak
ben.lubar.me.ap.brid.gy
I very much believe that if capitalism hadn't tried to turn large language models into infinite money and they were strictly in computer science land, people would find it really cool

the idea that weighted sums can independently figure out relative meanings of words via context clues is […]
Original post on mastodon.lubar.me
mastodon.lubar.me
November 23, 2025 at 4:13 AM
Reposted by DrYak
jaggakatja.bsky.social
The Nextclade dataset for Enterovirus D68 (EV-D68) has been realeased and is available on Nextclade!!
Enterovirus is an RNA virus that mostly causes respiratory illness, but is also suspected of causing a polio-like disorder called acute flaccid myelitis (AFM): en.wikipedia.org/wiki/Enterov...
November 20, 2025 at 1:42 PM
Reposted by DrYak
ai6yr.m.ai6yr.org.ap.brid.gy
The Verge: Screw it, I’m installing Linux

https://www.theverge.com/tech/823337/switching-linux-gaming-desktop-cachyos

#win11 #linux
To be clear, my desktop works fine on Windows 11. But the general ratio of cool new features to egregious bullshit is low. I do not want to talk to my computer. I do not want to use OneDrive. I’m sure as hell not going to use Recall. I am tired of Windows trying to get me to use Edge, Edge trying to get me to use Bing, and everything trying to get me to use Copilot. I paid for an Office 365 subscription so I could edit Excel files. Then Office 365 turned into Copilot 365, and I tried to use it to open a Word document and it didn’t know how. Meanwhile, Microsoft is ending support for Windows 10, including security updates, forcing people to buy new hardware or live with the risks.
November 20, 2025 at 5:27 AM
Reposted by DrYak
algocompsynth.mastodon.social.ap.brid.gy
Avrilcadabra - 20 mins of glorious chiptune | Bitscape 2025

https://youtu.be/Kk0HUPxJn_0
November 17, 2025 at 6:34 AM
Reposted by DrYak
greem.cyberplace.social.ap.brid.gy
A rather comical conjunction of posts just appeared in my timeline thanks to @cstross, XKCD and @lhcstatus2
Two consecutive posts. First is an XKCD cartoon lamenting hiring a particle physicist to design a water park, as they've included a graphite beam dump on a water slide. The second is a trip notification from the Large Hadron Collider, which probably resulted in the beam being sent into a graphite beam dump.
November 15, 2025 at 11:43 AM
dryak.mstdn.science.ap.brid.gy
My prediction:
When the new Steam Controller, "GabeCube", and Frame hit the market, #SteamDeck might get a 2nd refresh most likely with the same TMR analog stick as the rest of this products line-up, probably improved wireless (dual radios to facilitate streaming like the Frame?), perhaps […]
Original post on mstdn.science
mstdn.science
November 13, 2025 at 3:01 PM
Reposted by DrYak
bruces.mastodon.social.ap.brid.gy
November 8, 2025 at 3:28 AM
Reposted by DrYak
martin.boitam.eu.ap.brid.gy
Pour répondre à la clameur populaire, j'ai fait un petit site qui présente mon cours / atelier sur l'IA :

> Les tenants du bon sens et de la modération répètent que « la question n’est pas d’être pour ou contre les IA, mais de savoir comment les utiliser ». Je propose la perspective inverse […]
Original post on boitam.eu
boitam.eu
November 6, 2025 at 1:05 PM
Reposted by DrYak
viss.mastodon.social.ap.brid.gy
yo dawg
i heard you like linux
so i put linux in your linux so you could linux while you linux

https://www.phoronix.com/news/Linux-Kernel-WebAssembly
Linux Kernel Ported To WebAssembly - Demo Lets You Run It In Your Web Browser
Open-source developer Joel Severin today announced his work on porting the Linux kernel to WebAssembly and has successffully gotten the kernel up and running within WASM-capable web browsers...
www.phoronix.com
November 3, 2025 at 5:43 PM
Reposted by DrYak
jsbarretto.social.coop.ap.brid.gy
Thinking that I might start adding something like this to more of the software I write.
Text that reads: # Provenance This software is proudly and fondly written, maintained, used - and most crucially - understood by real human beings. While we can't personally attest to the provenance of every line of code ever contributed, the vast majority of the codebase has certainly been developed without the aid of large language models and other stochastic 'intelligence'. While the GPLv3 may not guarantee warranty 'of any kind', you can at least use this software in the comforting knowledge that its veracity and coherence is vouched for by sentient intelligence with skin in the game and a reputation to uphold. # Contribution guidelines We expect contributors to adhere to the ethos of the project. Source code is not an artifact, an intermediate representation, nor a bothersome annoyance whose creation is to be offloaded to metal and transistors. Source code is a source of truth - the only source of truth that constitutes this software project - and it deserves to be understood and curated by the accountable and reasoned mind of a human being. Please refrain from contributing changes that you have not personally understood and instigated the authorship of. We do not expect perfection, but we do expect you to personally understand your own motivations and decisions.
November 1, 2025 at 11:41 PM
Reposted by DrYak
ppxl.social.tchncs.de.ap.brid.gy
@Viss @catsalad yes but for your consideration:
Small car parking slot. Inside is parking a smol cat looking at the photographer
October 31, 2025 at 6:43 AM
Reposted by DrYak
b0rk.social.jvns.ca.ap.brid.gy
I know there are a lot of CSS magicians on the fediverse, is anyone open to freelance work? we're looking for some help with https://wizardzines.com

share a link to your site?
wizard zines
wizardzines.com
October 21, 2025 at 2:17 PM
Reposted by DrYak
fedi.arimelody.space
π
finally, π-thon. (python 3.14.0, released october 7th, 2025)
October 13, 2025 at 9:54 PM
Reposted by DrYak
kingu.sakurajima.moe.ap.brid.gy
With great power comes great electricity bill
October 11, 2025 at 1:41 PM
Reposted by DrYak
cremevax.infosec.exchange.ap.brid.gy
Bruce Schneier has a good high-level look at threat-modeling under an authoritarian government. Alas, it’s not amenable to a simple recipe approach, but involves carefully thinking through the tradeoffs […]

[Original post on infosec.exchange]
Screenshot of text that says: Being Innocent Won’t Protect You This is vital to understand. Surveillance systems and sorting algorithms make mistakes. This is apparent in the fact that we are routinely served advertisements for products that don’t interest us at all. Those mistakes are relatively harmless—who cares about a poorly targeted ad?—but a similar mistake at an immigration hearing can get someone deported. An authoritarian government doesn’t care. Mistakes are a feature and not a bug of authoritarian surveillance. If ICE targets only people it can go after legally, then everyone knows whether or not they need to fear ICE. If ICE occasionally makes mistakes by arresting Americans and deporting innocents, then everyone has to fear it. This is by design.
September 28, 2025 at 5:55 PM
Reposted by DrYak
handle.invalid
We’re happy to announce our study on tracing influenza A from wastewater has been published in Water Research. We developed a novel tiling amplicon approach, enabling deep genomic coverage and our method is now part of Swiss-wide wastewater surveillance efforts.
www.sciencedirect.com/science/arti...
Characterizing influenza A virus lineages and clinically relevant mutations through high-coverage wastewater sequencing
Influenza A virus poses significant public health challenges, causing seasonal outbreaks and pandemics. Its rapid evolution motivates continuous monit…
www.sciencedirect.com
September 23, 2025 at 7:51 AM
Reposted by DrYak
handle.invalid
Congratulations to Xiang Ge Luo for the Outstanding Student Paper award at ISMB/ECCB 2025 in Liverpool (www.iscb.org/ismbeccb2025...) for her work on the Bayesian inference of fitness landscapes via tree-structured branching processes published in Bioinformatics at doi.org/10.1093/bioi...
July 25, 2025 at 3:18 PM
Reposted by DrYak
handle.invalid
www.nature.com/articles/s41...

In our new study, we use mathematical modelling, simulations, and Swiss wastewater data to show that that key epidemiological metrics are not biased by differences in virus shedding. This highlights the robustness of wastewater monitoring for pathogen surveillance.
Estimated transmission dynamics of SARS-CoV-2 variants from wastewater are unbiased and robust to differential shedding - Nature Communications
Epidemiological estimates from wastewater are not biased by testing rates but may be subject to other biases. Here, the authors investigate the impact of variable virus shedding profiles for different...
www.nature.com
August 14, 2025 at 2:09 PM
Reposted by DrYak
vees.epistolary.org.ap.brid.gy
Attention Gen Xers and boomers with registered domain names 🚨

If you, like me, put a fictitious organization in your domain name registration 25 years ago because NetSol or ICANN did not allow you to leave that field blank, recent policy changes will make that organization name the *legal […]
Original post on epistolary.org
epistolary.org
September 19, 2025 at 1:38 PM
Reposted by DrYak
marcrr.ecoevo.social.ap.brid.gy
Lorenzen: unlike polar bears, Bowhead whales had stable environment suitability and genomic population size until very recently. Then human hunting (whaling) arrived, leading to a demographic crash. Modeling predicts that population recovery will be very slow at best. #bc2basel
September 10, 2025 at 7:28 AM