Dovetail Genomics
@dtgenomics.bsky.social
31 followers 1 following 58 posts
🧬 The Genome • Unrestricted 🧪
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dtgenomics.bsky.social
🚀 The Dovetail Analysis Portal (DAP) just expanded to support epigenetics!

Go from FASTQ files to interactive 3D genomic insights — fast, simple, and affordable.

👉 Sign up to try the test dataset or book a run-through:

🔗 portal.cantatabio.co...
🔗 cantatabio.com/dovet...
dtgenomics.bsky.social
We’re heading to #ASHG25 in Boston! 🎉
📍 Booth #1130 | Oct 14–18

🧬 Poster Session:
Oct 15, 2:30–4:30 PM — Subclonal Genomic Rearrangements
Oct 17, 2:30–4:30 PM — SVs drive enhancer hijacking in ovarian cancer

Meet us: go.dovetailgenomics....

#LinkPrep #CancerGenomics
dtgenomics.bsky.social
Dovetail Genomics are proud to sponsor the upcoming 6th Meeting of the Melbourne Epigenetics Club on Oct 7 at Uni of Melbourne. Thanks to @MelbEpigenetics for bringing the community together. Free attendance + snacks!
dtgenomics.bsky.social
🧬 New reference genome for the California vole! Built with PacBio HiFi + Dovetail® Omni-C®, this high-quality assembly offers insights into vole evolution, chromosomal diversity & conservation of endangered subspecies like the Amargosa vole. 👏 Congrats to the authors! doi.org/10.1093/jher...
dtgenomics.bsky.social
We’re heading to Epigenetics & Epigenomics in Health & Disease 2025 in Brussels, 24–26 Sept! Miles Collier, our Director of Sales, EMEA, will be there and eager to connect. Attending too? Comment below and Miles will reach out. Let’s meet in Brussels!

#Epigenetics2025 #Genomics #DovetailGenomics
dtgenomics.bsky.social
🪶 Two birds, one powerful technology! 🧬
Chromosome-scale de novo assemblies of the Eurasian Woodcock & Jack Snipe are now live. Built combining long- & short-read sequencing, scaffolded with Dovetail® Omni-C® (Hi-C) data. Assemblies are now public in GenBank.
🔗 doi.org/10.56179/001...
dtgenomics.bsky.social
🚨 New Webinar Recording 🚨
Ask the Experts: Functional Genome Annotation w/ Dr. Martin Kollmar (GOENOMICS). Why rigor matters, spotting flawed datasets, BUSCO limits, assembly quality, & best practices for reliable, actionable genome insights.

🔗 Access full recording here: go.dovetailgenomics....
dtgenomics.bsky.social
Publication alert: European cisco adapts to fresh & brackish waters while maintaining spring- & autumn-spawning groups. 🐟 An HQ chromosome-scale assembly powered by Omni-C® uncovered genomic signals of ecological adaptation & reproductive timing. 🧬 Kudos to the research team for their great work!
European cisco
dtgenomics.bsky.social
That’s a wrap on the 2025 Queenstown Research Week! 🎉 Thanks to everyone who stopped by booth #22. It was great sharing how the Dovetail® LinkPrep™ assay expands short-read sequencing — enabling base pair–resolved variant detection, 3D genome mapping & more. Missed us? 👉 ow.ly/BBew50WQXxH
dtgenomics.bsky.social
We’re excited to be at the 2025 NIH Research Festival in Bethesda, MD!

Don't miss our workshop:
“Genomic Characterization of Multiple Myeloma Relapse with the LinkPrep™ Assay”

📍 Room 6, NIH Main Bethesda
📅 Thursday, September 11th | 1:45-2:45 PM
🔗 Register: ow.ly/ioBz50WRpCP
dtgenomics.bsky.social
New study in Nature Communications reveals how EBV reshapes the 3D genome in nasopharyngeal carcinoma, hijacking KDM5B (a histone demethylase) to drive cancer progression. Proud that Dovetail Omni-C® technology enabled the high-res chromatin mapping behind these insights. 🧬 www.nature.com/artic...
dtgenomics.bsky.social
We’re excited to be part of 2025 Queenstown Research Week!

Come chat with us at booth #22! Discover how Dovetail® LinkPrep™ technology expands the capabilities of short-read sequencers — enabling base pair–resolved variant detection, high-resolution 3D genome mapping, and more.
dtgenomics.bsky.social
🧬 New Article in Nucleic Acids Research: Haplotype-resolved de novo assembly uncovers the unique genetic footprint of alternative lengthening of telomeres (ALT) in mouse stem cells. With Dovetail® Micro-C, researchers uncovered complex variants, mTALT & stability genes. 🔗 doi.org/10.1093/nar/...

dtgenomics.bsky.social
⏳ Just 2 days to go! Join Dovetail Genomics at the San Francisco Multiomics Mixer: Tacos & Tech this Thursday, Aug 28 at Latch Bio 🧬 Science, networking & tacos await. 🌮 Free event — register now: ow.ly/1X2w50WISIY
dtgenomics.bsky.social
🌮 Dovetail is proud to co-sponsor the San Francisco Multiomics Mixer: Tacos & Tech (Aug 28) — come for the tacos, stay for the science! 🧬 Connect with the Bay Area life sciences community for an evening of discovery, networking, and tacos! ✨ Free to attend — register here: ow.ly/1X2w50WISIY
dtgenomics.bsky.social
🌱 For this genome, the grass was greener on the Dovetail side.

🧬 Chromosome-level genome assembly of Zoysia macrostachya reveals 33K+ protein-coding genes and insights into salt tolerance — advancing resilient crop science and turfgrass breeding.

Read more: doi.org/10.1038/s415...
dtgenomics.bsky.social
🧬 We’re thrilled to be exhibiting at the 2025 HGSA Annual Scientific Meeting in Sydney, Australia!

Visit us at booth #31 to learn how Dovetail® LinkPrep™ technology expands the capabilities of short-read sequencers, enabling base pair–resolved detection of structural variants.
dtgenomics.bsky.social
🧬 New neuroblastoma study reveals how histone-modifying complex component RCoR2 is—unexpectedly—a transcriptional activator essential for maintaining enhancer–promoter loops that drive oncogenic pro-survival gene expression. [Revealed using our MNase-HiChIP Kit] 🧪 doi: 10.1016/j.celrep.2025.115951
dtgenomics.bsky.social
Researchers used Dovetail’s HiChIP kit to map enhancer–promoter interactions driving high-altitude adaptation in Tibetan pigs.

Integration of genomic, RNA-seq, ATAC-seq, and HiChIP data revealed key regulatory variants that modulate gene expression under hypoxia.
academic.oup.com/mbe/article/...
Integrative Genomic, Transcriptomic and Epigenomic Analysis Reveals cis-regulatory Contributions to High-altitude Adaptation in Tibetan Pigs
dtgenomics.bsky.social
🧬 Using Dovetail Omni-C® + Nanopore, researchers built chromosome-scale genomes for 3 Meretrix clams — including a likely novel species! 🦪 A big leap for aquaculture, adaptation studies, marine biodiversity & evolutionary biology 🌊
📖 Find out more: www.nature.com/artic...
dtgenomics.bsky.social
🔬 Researchers from UWA, AGRF, SCGH & Dovetail team used Micro-C to build the first 3D regulatory atlas of human osteoclasts — linking non-coding GWAS variants to gene targets and opening new paths for understanding bone disease like osteoporosis 🦴
🔗 doi.org/10.1093/jbmr...
#3DGenomics #Multiomics
dtgenomics.bsky.social
🐸 New genomic resources for the endangered alpine tree frog (Litoria verreauxii alpina)!

A chromosome-scale assembly, scaffolded with Dovetail® LinkPrep™ data, offers key insights for conservation and reproductive biology.

📖 f1000research.com/ar...

#Genomics #HiC #Conservation

dtgenomics.bsky.social
🧬 Marchantia quadrata’s genome reveals a convergent path to cosexuality!

🌿 A new Cell Reports study reveals how M. quadrata retained the V chromosome, lost the U, and relocated Feminizer — all uncovered through an Omni-C® powered genome assembly.

🔗 www.cell.com/cell-re...

#PlantGenomics
dtgenomics.bsky.social
🌲 Big step for big genomes: Cryptomeria japonica’s ~11 Gb genome was assembled to chromosome level using PacBio HiFi contigs + Omni-C® scaffolding for anchoring. Published in BMC Genomics (Nov 2024), this work advances conifer genomics. 🧬

🔗 ow.ly/QTvI50WtqvN

#GenomeAssembly #OmniC