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Morgan Carter @morgancarterphd.bsky.social · Jul 17

#2027ISMPMI - Try 2 for Jeju, Korea!

Hope to see you there and I’m glad that South Korea gets to host after their turn was missed because of the pandemic.

There is a promise of good food 🤤

Though I may need to start saving up now with the state of things…
#2025ISMPMI

A landscape photo with the text “especially in 2027, the IS-MPMI Congress held on the beautiful Jeju Island will offer you an unforgettable and special experience”

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Isabel saur @izzysaurlab.bsky.social · Jul 17

Mary wildermuth #2025ISMPMI gives the best introduction to the Powdery mildew fungus :)

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Songyuan Zhang from the Zipfel lab is learning from nature how to engineer new MAMP receptors. Great results.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Benjamin Menn presents an elegant yeast surface displace screen to identify new carbohydrate binding receptors of plants.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Thi Bich Luu wants to make a difference by transferring Nod factor susceptibility to barley, maize and other cereals. Taking candidate homolgs of NFR5 receptor and by domaine swapping chimaric receptors are build.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Rhizobia and Haber-Bosch good bye? Luis Rubio goes for the challenge on reconstituting nitrogen fixation directly in plants by targeting around 20 needed components in Mitochondria in a step-wise process.

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Suayb Üstün @suaybuestuen.bsky.social · Jul 17

@kenichitsuda.bsky.social is introducing the Concurrent sessions on biotic/abiotic trade-offs in plant-microbe interactions #2025ISMPMI

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Gitta Coaker @gittacoaker.bsky.social · Jul 17

www.biorxiv.org/content/10.1...
Up next at #2025ISMPMI @kseniakrasileva.bsky.social discussing work on protein language model for receptor engineering.

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Morgan Carter @morgancarterphd.bsky.social · Jul 17

@kseniakrasileva.bsky.social is the first talk at the engineering traits session at #2025ISMPMI

Branching into PRRs thanks to @danimstevens.bsky.social.

The ?: Can we use language models to predict host and microbe proteins interaction outcomes?

The answer: Yes! New “mamp-ml”does pretty well.

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Sebastian Schornack @dromius.bsky.social · Jul 17

#2025ISMPMI - first new to nature chimeric NLR sensors being created, with integrated domains that do not have sequence or structure matches in the recorded life - raises questions on assessing biosafety & food safety aspects for these immune receptors for lab and field studies.

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Morgan Carter @morgancarterphd.bsky.social · Jul 17

@angusb.bsky.social wants to engineer plant resistance proteins (NLRs) from scratch.

Can we create protein domains to integrate into NLRs to catch pathogen effectors? New tech makes this possible now.

Chose Magnaporthe and Fusarium effectors as targets - many steps later, it worked!
#2025ISMPMI

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Morgan Carter @morgancarterphd.bsky.social · Jul 17

Dani’s recent paper appears to be the top #2025ISMPMI post which is impressive for someone not here 💓
bsky.app/profile/dani...

Dani Stevens, Ph.D. @danimstevens.bsky.social · Jul 15

#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible!

Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵

www.biorxiv.org/content/10.1...

mamp-ml: A deep learning approach to epitope immunogenicity in plants

Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...

www.biorxiv.org

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Morgan Carter @morgancarterphd.bsky.social · Jul 17

In the trait engineer session and Aurelia Rakotondrafara makes a quip that her talk has no AI 😅

Under-revision-study from her lab uses a treatment of a mycovirus protein to reduce growth and increase fungicide susceptibility of the pathogen Sclerotinia sclerotiorum.
#2025ISMPMI

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Aurelie Rakotondrafara shows very interesting effects of mycovirus infection of Sclerotinia on virulence on the host plant. Take home to use mycoviruses and plant viruses to limit the spread of fungal pathogens.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Agnus Bucknell of the Talbot lab gives an exciting presentation to engineer fungal effectors recognizing immune sensors based on Pik1. Great and clear talk.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Ksenia Krasileva gives an impressive talk on predicting receptor-ligand interactions. CHECK OUT mamp-ml!

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Tatsuya Nobori @tatsuyanobori.bsky.social · Jul 17

TODAY. 15:15 @ Room P&Q #2025ISMPMI

Tatsuya Nobori @tatsuyanobori.bsky.social · Jun 27

#ISMPMI2025 attendees!

Bookmark our concurrent session co-organized with @uprogress.bsky.social featuring exciting talks on the spatial and temporal regulation of plant–microbe interactions.

We have 3 invited speakers: Feng Zhou, @lluginbuehl.bsky.social @type3lab.bsky.social

and…

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Oswaldo Valdes-Lopez points out that other nutrients beside Nitrogen limitation are important cues to decide on symbiosis with rhizobia. Phosphate limitation negatively impacts nodule formation.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Evans Lagudah gives a beautiful and clear talk on the challenge to find durable and broad resistances. Most are genes of whatever type show race specificity but Lr34, Lr67 and Lr46 are encoding for membrane transporters showing a pathogen-attenuating resistance.

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Suayb Üstün @suaybuestuen.bsky.social · Jul 17

We start the last day of #2025ISMPMI with Renier van der Hoorn who will present his pioneering work on how pathogens manipulate apoplastic defence

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Morgan Carter @morgancarterphd.bsky.social · Jul 17

Jian-Min Zhou shows unpublished data related to ZAR1 signaling and what other players are required in planta for activation of the resistosome and localization in the plasma membrane.
Find similarity with a salt stress response.
#2025ISMPMI

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI Jian-Min Zhou calls for more interdisciplinary approaches in plant microbe research to bring our research to the next level. He gives insights on ZAR1 signalling. Zar1 influences SYT1 distribution in a Ca2+ binding dependent manner.

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Armin Djamei @effectomics.bsky.social · Jul 17

#2025ISMPMI the great Renier van der Hoorn starts the plenary with exciting research about the apoplastic battlefield in bacterial-plant interactions. Hydrolases and inhibitors all around...glycosyrin inhibitor pathway is conserved and spread inhibiting galactosidases and glucosidases.

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Team_Zuccaro @algazuccaro.bsky.social · Jul 16

Arabidopsis thaliana CELLOX1 limits fungal colonization in roots. Nice talk by Giulia Peruzzi at #2025ISMPMI, @ceplas.bsky.social

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Saskia Hogenhout @saskiahogenhout.bsky.social · Jul 16

www.science.org/doi/10.1126/...

Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies

Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.

www.science.org

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