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Ellen Rim @ellenrim.bsky.social · 5d

Reading this 👀 new tool for in vivo plant protein selection www.science.org/doi/10.1126/...

Engineered geminivirus replicons enable rapid in planta directed evolution

Directed evolution can rapidly generate genetic variants with new and enhanced properties, yet efficient platforms for performing such evolution directly in plant cells have been lacking. We developed...

www.science.org

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Ellen Rim @ellenrim.bsky.social · Aug 23

Thank you Jongmin :)

Ellen Rim @ellenrim.bsky.social · Aug 20

And my awesome long-term collaborator in science and life
@jimnotwell.bsky.social

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Ellen Rim @ellenrim.bsky.social · Aug 20

Friends who shared their job search experience with me, @claudiaraudia.bsky.social, Flor, Lay Teng, Kyle, Berfin

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Ellen Rim @ellenrim.bsky.social · Aug 20

Ronald lab folks for endless support, feedback, and tolerating my play-by-play

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Ellen Rim @ellenrim.bsky.social · Aug 20

My mentors for their feedback on talks and kind encouragement, @gittacoaker.bsky.social Dinesh, Valley, and Richard

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Ellen Rim @ellenrim.bsky.social · Aug 20

Academic job search takes a village. I'd like to thank mine - my postdoc mentor @pcronald.bsky.social and PhD mentor Roel for all their wisdom and support throughout the years

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Ellen Rim @ellenrim.bsky.social · Aug 20

Really excited to join Stanford ChemE this September! We'll engineer proteins in plant immune and hormone pathways, combining high-throughput directed evolution with ML. Our goal is to enhance climate stress resilience and disease resistance in crops: rim.stanford.edu

Harnessing synthetic biology to engineer resilient crops

rim.stanford.edu

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Ellen Rim @ellenrim.bsky.social · Jul 8

Found last season's EquiSciTrack series helpful for the job search!

Ellen Rim @ellenrim.bsky.social · Jun 14

Sorry this happened. Wow…

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Ellen Rim @ellenrim.bsky.social · Jun 10

Congratulations Susanna!

Ellen Rim @ellenrim.bsky.social · Apr 26

Studying wild varieties resistant to HLB led to a peptide solution to HLB in cultivated citrus. Peptide that blocks a susceptibility gene. Down the road hopefully this gene can be CRISPR edited to its DN form and save the oranges

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Ellen Rim @ellenrim.bsky.social · Apr 26

Studying wild resistant varieties -> basic biology -> a solution to a devastating disease in citrus. Pretty amazing

Dan Kliebenstein @spicybotrytis.bsky.social · Apr 10

I had fun collaborating about conceptualization susceptibility loci and evolution constraining downstream ability to evolve new resistances. Really need to better understand gene, network and species extinction in plant lineages.
www.science.org/doi/10.1126/...

Targeted MYC2 stabilization confers citrus Huanglongbing resistance

Huanglongbing (HLB) is a devastating citrus disease. In this work, we report an HLB resistance regulatory circuit in Citrus composed of an E3 ubiquitin ligase, PUB21, and its substrate, the MYC2 trans...

www.science.org

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Ellen Rim @ellenrim.bsky.social · Apr 25

So exciting!!! Congratulations Mari 🥳🥳

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Reposted by Ellen Rim

UCDavisPlants @ucdavisplants.bsky.social · Apr 18

🌱From Nature Genetics: RWT4, a wheat tandem kinase protein, directly binds and phosphorylates a fungal effector to trigger defense - highlighting TKPs as effector sensors. (Yi-Chang Sung, Suji Baik, Gitta Coaker)
▶️ www.nature.com/articles/s41...

Wheat tandem kinase RWT4 directly binds a fungal effector to activate defense - Nature Genetics

This study shows that RWT4, a wheat tandem kinase, confers resistance to the fungal pathogen Magnaporthe oryzae by directly binding to the pathogen effector AvrPWT4 and activating host defense.

www.nature.com

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Ellen Rim @ellenrim.bsky.social · Apr 18

Toddler and i enjoy the same book somehow

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Ellen Rim @ellenrim.bsky.social · Apr 5

Agreed, and editing-based disease resistance solutions that are head and shoulders above current options are one way forward

Ellen Rim @ellenrim.bsky.social · Apr 5

Three reasons for "almost no commercially available plant varieties carrying biotech-derived disease resistance traits" according to authors: 1. Disease resistance and the defense response are complicated 2. Plant breeders are good at their jobs 3. Disease resistance is a constantly moving target

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Ellen Rim @ellenrim.bsky.social · Apr 5

I've also been thinking about this: "Why Are There So Few Commercially Successful Crop Varieties Engineered for Disease Resistance?"
bsppjournals.onlinelibrary.wiley.com/doi/10.1111/...

It‘s Complicated: Why Are There So Few Commercially Successful Crop Varieties Engineered for Disease Resistance?

It is more than 40 years since the era of transgenic plants began and more than 30 years after the cloning of the first plant disease resistance genes. Despite extensive progress in our mechanistic u....

bsppjournals.onlinelibrary.wiley.com

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Reposted by Ellen Rim

Claudio Cantù @claudiocantu81.bsky.social · Mar 20

If you are a #WNT lover (who is not?) you cannot miss the incoming Grodon Research Conference
www.grc.org/wnt-signalin...
and the preceeding GRSeminar
www.grc.org/wnt-signalin...
a unique forum for younger scientists to present their work

👉 Please help me spread the word and RT (or RB?)!🙏

2025 Wnt Signaling Conference GRC

The 2025 Gordon Research Conference on Wnt Signaling will be held in Lewiston, Maine. Apply today to reserve your spot.

www.grc.org

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Ellen Rim @ellenrim.bsky.social · Mar 18

Wow excited to read!

Ellen Rim @ellenrim.bsky.social · Mar 12

Thank you for representing ag researchers at the rally and sharing these thoughts - also wondering the same!

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Ellen Rim @ellenrim.bsky.social · Feb 21

Former USDA employee (and a UC Davis colleague) terminated days before her due date: "We wouldn't have food without our farmers. A lot of us working for the USDA, that's what we do, we support American farmers"
abcnews.go.com/Politics/vid...

Video Former USDA employee terminated days before her due date

Justine Beaulieu was impacted by the Trump layoffs days before she was due to give birth, losing her maternity leave and her health insurance in limbo.

abcnews.go.com

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Reposted by Ellen Rim

Innovative Genomics Institute @innovativegenomics.bsky.social · Feb 19

We're celebrating our 10th anniversary this year and remembering some great moments from the past decade! In February 2022, IGI's Pam Ronald won the Wolf Prize in Agriculture for her “pioneering work on disease resistance and environmental stress tolerance in rice.”

Read more: ow.ly/kAqe50UPW9s

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Ellen Rim @ellenrim.bsky.social · Feb 6

A tour de force starting with C. elegans juice that identified a nematode peptide MAMP-plant immune receptor pair

Yasuhiro Kadota @yasukadota.bsky.social · Feb 3

Excited to share our new publication on a novel MAMP peptide conserved across nematodes, insects, and fungal pathogens, along with the RLK essential for its signaling. www.biorxiv.org/content/10.1...

A trehalase-derived MAMP triggers LecRK-V-mediated immune responses in Arabidopsis

Plant-parasitic nematodes (PPNs) cause major agricultural losses worldwide, yet the molecular basis of plant immunity against these pathogens remains poorly understood. To investigate how plants recog...

www.biorxiv.org

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