Dan Kliebenstein
@spicybotrytis.bsky.social
1.9K followers 430 following 1.3K posts
Dogs, Horses and Gardening, with a side of research on complexity and metabolic warfare in plants
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spicybotrytis.bsky.social
I feel like that title should be “a plant pathogens advance”.
spicybotrytis.bsky.social
I am not sure that reviewers really dive into the logic of ideas over their feel.
spicybotrytis.bsky.social
Systems of systems get even nuttier.
spicybotrytis.bsky.social
Host-pathogen cotranscriptome papers are really intricate to write as you have genes that are host influenced, pathogen influenced and interaction influenced in both the host and the pathogen.
spicybotrytis.bsky.social
I promise the low monotone makes it the perfect recording to induce sleep.
Reposted by Dan Kliebenstein
somssich.bsky.social
Our article "Guns in Rosettes: The Arabidopsis chemical weapons arsenal" is finally published @plantphys.bsky.social!
You can download the #OpenAccess PDF here:

doi.org/10.1093/plph...

But real connoisseurs of #AntimicrobialCompounds will want to get the vinyl boxset: #PlantScience #PlantImmunity
A vinyl box with six colored vinyl LPs sticking out of its right side. The Title "Guns in Rosettes" is on top, with the subtitle "The Arabidopsis chemical weapons arsenal" just below. Then there is an Arabidopsis plant with machine guns sticking out. Below is the statement "6-LP LIMITED EDITION COLORED VINYL BOX SET" The back cover of the vinyl box set showing the tracklist:
1. Methionine-derived compounds
    Aliphatic GSLs
2. Tryptophan-derived compounds (trptonites)
    Indolic GSLs
    Camalexin
    Hycanite (4-OH-ICN)
3. Phenylalanine-derived compounds (phenylpropanoids)
    Benzenic GSLs
    Coumarins
    Hydroxycinnamates
    Flavonoids
4. Terpenoids
    (E)-β-caryophyllene
    α- and β-pinene
    Thalianin, arabidin, and DMNT

And the statement "Recorded live in front of an audience in 2025"
spicybotrytis.bsky.social
Statistics has never been about coding, it is about experimental design, appropriate application and interpretation.
spicybotrytis.bsky.social
You would be surprised how many assume plants only have fight options. The idea of over-compensation has very little saturation in the molecular community interested in growth vs defense tradeoffs.
spicybotrytis.bsky.social
I am wondering if it is more 50/50 for primary but specialized rapidly collapse into primary catabolism. Quicker than synthesis diverges.
spicybotrytis.bsky.social
In response to herbivory they can fight, evade or even over compensate. The later two are development as defense.
spicybotrytis.bsky.social
That is kind of my gut. How would you split Anabolism vs catabolism? And how does energy differ across CNSP? Or is that super lineage specific?

As in Barley with 20% cyanogen dry weight is just wack.
spicybotrytis.bsky.social
Thinking of the standard senntence saying “because plants are sessile they …”. Is the direction arrow correct? Or is sessile not a cause but a consequence?

I.e. because plants are autotrophic, they are sessile.
spicybotrytis.bsky.social
If you were the predicting sort, how much of a plants metabolism would be in the following four categories?

Primary Anabolism
Primary Catabolism
Specialized Anabolism
Specialized Catabolism

Feel free to define "how much" by gene #, enzyme #, flux fraction, etc.

And your own 1 v 2 defn.

#secmet
spicybotrytis.bsky.social
At least it didn't autocorrect to sweetbreads.
spicybotrytis.bsky.social
We did some modelling using Arabidopsis population parameters and the typical enzyme gene will be fixed for stop codons in about 10,000 generations once it has 0 effect on fitness. Unsure how to model whole gene deletion events as we see whole gene deletions more then fixed stops.
spicybotrytis.bsky.social
Non-equlibrium systems, solid state, etc. Never seems to work. If they are set in that biologists are just stamp collecting doofuses then it is impossible to move them off that.
spicybotrytis.bsky.social
That is actually what physicists or engineers come back with and I've never been able to dissuade them. It is the expert-expert argument that I find hard.
spicybotrytis.bsky.social
Still won't make a dent. It is so hard to get past the "We largely solved how the Universe works, how can one individual be more complex than that?" counter argument.
spicybotrytis.bsky.social
Yep, the choice with apple trees is spray a lot of pesticide or always use a knife.
spicybotrytis.bsky.social
That is why every western movie shows a knife being used to cut the apple first. Not for Eastwood to be dramatic and slow but so he didn't eat a worm.
spicybotrytis.bsky.social
So would an accurate prediction be that only anthocyanins are missing from these lineages and proanthocyandins must still be a key component of the Caryophyllales metabolism? From the glucosinolate realm, if a gene has no function it is gone before a new species arises.
spicybotrytis.bsky.social
Given the number of posts of similar context across the years, accuracy and precision might be overlapping.
spicybotrytis.bsky.social
If one can’t be Linneaen specific on vegetables, when can one be?
spicybotrytis.bsky.social
Nerd needless precision alert; none of those are mustard. That would be Brassica nigra or Sinapus alba.